Family history in public health practice: a genomic tool for disease prevention and health promotion [0.03%]
公共卫生实践中的家族史:疾病预防和健康促进的基因组工具
Rodolfo Valdez,Paula W Yoon,Nadeem Qureshi et al.
Rodolfo Valdez et al.
Family history is a risk factor for many chronic diseases, including cancer, cardiovascular disease, and diabetes. Professional guidelines usually include family history to assess health risk, initiate interventions, and motivate behavioral...
Teen fertility in transition: recent and historic trends in the United States [0.03%]
转型中的青少年生育率:美国近期及历史上的趋势变化
John S Santelli,Andrea J Melnikas
John S Santelli
After considerable declines in teen birth and pregnancy rates between 1991 and 2005, teen birth rates rose unexpectedly in 2006 and 2007. To understand these recent trends, we examined historical changes in fertility, trends in sexual behav...
Tim Byers
Tim Byers
The close of the twentieth century brought historic changes in cancer risk factors, early detection, and treatment. As a consequence, we have seen two decades of steadily declining risk of death from cancer in the United States. The reasons...
Helen I Woodward,Oliver T Mytton,Claire Lemer et al.
Helen I Woodward et al.
Medical errors and adverse events are now recognized as major threats to both individual and public health worldwide. This review provides a broad perspective on major effective, established, or promising strategies to reduce medical errors...
Approaches to uncertainty in exposure assessment in environmental epidemiology [0.03%]
环境流行病学中暴露评估的不确定性处理方法
Donna Spiegelman
Donna Spiegelman
Uncertainty in assessment of individual exposure levels leads to bias, often, but not always, toward the null in estimates of health effects, and to underestimation of the variability of the estimates, leading to anticonservative p-values. ...
Health in all policies-the Finnish initiative: background, principles, and current issues [0.03%]
健康融入所有政策——芬兰的举措:背景、原则及当前问题
Pekka Puska,Timo Ståhl
Pekka Puska
Many historical developments, such as the Alma Ata Declaration or the Ottawa Charter, have drawn attention to the need for intersectoral work and for considering the health aspects of different policy proposals. In the 1970s, Finland starte...
Artemis P Simopoulos
Artemis P Simopoulos
All diseases have a genetic predisposition. Genome-wide association studies (GWASs) by large international consortia are discovering genetic variants that contribute to complex diseases. However, nutrient information is missing, which is es...
Methods for investigating gene-environment interactions in candidate pathway and genome-wide association studies [0.03%]
候选途径和全基因组关联研究中探究基因-环境互作的统计方法
Duncan Thomas
Duncan Thomas
Despite the considerable enthusiasm about the yield of novel and replicated discoveries of genetic associations from the new generation of genome-wide association studies (GWAS), the proportion of the heritability of most complex diseases t...
The behavioral response to personalized genetic information: will genetic risk profiles motivate individuals and families to choose more healthful behaviors? [0.03%]
个性化遗传信息的行为反应:基因风险谱系会促使个体和家庭选择更健康的生活方式吗?
Colleen M McBride,Laura M Koehly,Saskia C Sanderson et al.
Colleen M McBride et al.
This report describes the use of information emerging from genetic discovery to motivate risk-reducing health behaviors. Most research to date has evaluated the effects of information related to rare genetic variants on screening behaviors,...
Stavros Garantziotis,David A Schwartz
Stavros Garantziotis
Gene-environment interactions are the indisputable cause of most respiratory diseases. However, we still have very limited understanding of the mechanisms that guide these interactions. Although the conceptual approaches to environmental ge...