Complementary roles of the main and accessory olfactory systems in mammalian mate recognition [0.03%]
主嗅觉系统和辅助嗅觉系统在哺乳动物配偶识别中的互补作用
Michael J Baum,Kevin R Kelliher
Michael J Baum
We review studies conducted in mouse and ferret that have specified roles of both the main and the accessory olfactory nervous systems in the detection and processing of body odorants (e.g., urinary pheromones, extraorbital lacrimal gland s...
Steven D Munger,Trese Leinders-Zufall,Frank Zufall
Steven D Munger
The mammalian olfactory system senses an almost unlimited number of chemical stimuli and initiates a process of neural recognition that influences nearly every aspect of life. This review examines the organizational principles underlying th...
Stem cells, self-renewal, and differentiation in the intestinal epithelium [0.03%]
肠道上皮中的干细胞、自我更新和分化
Laurens G van der Flier,Hans Clevers
Laurens G van der Flier
The mammalian intestine is covered by a single layer of epithelial cells that is renewed every 4-5 days. This high cell turnover makes it a very attractive and comprehensive adult organ system for the study of cell proliferation and differe...
Mechanisms of muscle degeneration, regeneration, and repair in the muscular dystrophies [0.03%]
肌营养不良症中肌肉退化、再生和修复的机制
Gregory Q Wallace,Elizabeth M McNally
Gregory Q Wallace
To withstand the rigors of contraction, muscle fibers have specialized protein complexes that buffer against mechanical stress and a multifaceted repair system that is rapidly activated after injury. Genetic studies first identified the mec...
Jang H Youn,Alicia A McDonough
Jang H Youn
The potassium homeostatic system is very tightly regulated. Recent studies have shed light on the sensing and molecular mechanisms responsible for this tight control. In addition to classic feedback regulation mediated by a rise in extracel...
Convergent evolution of alternative splices at domain boundaries of the BK channel [0.03%]
大型钙激活钾通道BK的结构域边界处的外显子相异剪接的汇聚式演化
Anthony A Fodor,Richard W Aldrich
Anthony A Fodor
Alternative splicing is a widespread mechanism for generating transcript diversity in higher eukaryotic genomes. The alternative splices of the large-conductance calcium-activated potassium (BK) channel have been the subject of a good deal ...