MicroRNAs and their Modulatory Effect on the Hallmarks of Osteosarcopenia [0.03%]
微小核糖核酸及其对骨肌衰老标志的影响
William J Silva,André Cruz,Gustavo Duque
William J Silva
Purpose of the review: Osteosarcopenia is a geriatric syndrome associated with disability and mortality. This review summarizes the key microRNAs that regulate the hallmarks of sarcopenia and osteoporosis. Our objective w...
Persistent uncertainties in optimal treatment approaches of secondary hyperparathyroidism and hyperphosphatemia in patients with chronic kidney disease [0.03%]
慢性肾脏病继发性甲状旁腺功能亢进和高磷血症治疗方案的不确定性分析
Daniela Del Pilar Via Reque Cortes,Tilman B Drueke,Rosa Maria Affonso Moysés
Daniela Del Pilar Via Reque Cortes
Purpose of review: This review is a critical analysis of treatment results obtained in clinical trials conducted in patients with chronic kidney disease (CKD) and secondary hyperparathyroidism (SHPT), hyperphosphatemia, o...
2D vs. 3D Evaluation of Osteocyte Lacunae - Methodological Approaches, Recommended Parameters, and Challenges: A Narrative Review by the European Calcified Tissue Society (ECTS) [0.03%]
二维与三维评价骨细胞腔：方法学途径，推荐参数及挑战——欧洲钙化组织学会（ECTS）的叙事综述
Annika Vom Scheidt,Johannes Krug,Patricia Goggin et al.
Annika Vom Scheidt et al.
Purpose of review: Quantification of the morphology of osteocyte lacunae has become a powerful tool to investigate bone metabolism, pathologies and aging. This review will provide a brief overview of 2D and 3D imaging met...
Molecular Deconvolution of Bone Marrow Adipose Tissue Interactions with Malignant Hematopoiesis: Potential for New Therapy Development [0.03%]
骨髓脂肪组织与恶性血液系统肿瘤相互作用的分子拆分：潜在的新药研发方向
Drenka Trivanović,Marko Vujačić,Rossella Labella et al.
Drenka Trivanović et al.
Purpose of review: Along with a strong impact on skeletal integrity, bone marrow adipose tissue (BMAT) is an important modulator of the adult hematopoietic system. This review will summarize the current knowledge on the c...
Lena Batoon,John R Hawse,Laurie K McCauley et al.
Lena Batoon et al.
Purpose of review: This review summarizes the recently published scientific evidence regarding the role of efferocytosis in bone dynamics and skeletal health. ...
Photon-Counting Computed Tomography for Microstructural Imaging of Bone and Joints [0.03%]
用于骨和关节微结构成像的单光子计数CT技术
Jilmen Quintiens,G Harry van Lenthe
Jilmen Quintiens
Purpose of review: Recently, photon-counting computed tomography (PCCT) has been introduced in clinical research and diagnostics. This review describes the technological advances and provides an overview of recent applica...
Mitchell N Froemming,Sundeep Khosla,Joshua N Farr
Mitchell N Froemming
Purpose of review: Beyond aging, senescent cells accumulate during multiple pathological conditions, including chemotherapy, radiation, glucocorticoids, obesity, and diabetes, even earlier in life. Therefore, cellular sen...
Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging [0.03%]
生理状态下骨髓微环境中的骨骼细胞和造血细胞的相互作用及衰老时的变化
Emily R Quarato,Noah A Salama,Laura M Calvi
Emily R Quarato
Purpose of the review: In this review, we discuss the most recent scientific advances on the reciprocal regulatory interactions between the skeletal and hematopoietic stem cell niche, focusing on immunomodulation and its ...
Insights into Craniofacial Development and Anomalies: Exploring Fgf Signaling in Zebrafish Models [0.03%]
斑马鱼模型中Fgf信号在颅面发育及异常中的作用机制研究
Rachel Pereur,Emilie Dambroise
Rachel Pereur
Purpose of review: To illustrate the value of using zebrafish to understand the role of the Fgf signaling pathway during craniofacial skeletal development under normal and pathological conditions. ...
Quercetin in Osteoporosis Treatment: A Comprehensive Review of Its Mechanisms and Therapeutic Potential [0.03%]
檞皮素在骨质疏松症治疗中的作用机制及其潜在疗效的全面综述
Yanchen Feng,Xue Dang,Pan Zheng et al.
Yanchen Feng et al.
Purpose of review: This review aims to provide a theoretical basis and insights for quercetin's clinical application in the prevention and treatment of osteoporosis (OP), analyzing its roles in bone formation promotion, b...