Astrid D Bakker,Victor J B van Santen
Astrid D Bakker
Purpose of Review: Osteocytes form an extensive cellular network and communicate both with neighboring bone cells and with distant organs. Here, we review evidence on which tissues osteocytes communicate with, and the mol...
PHEWAS, TWAS, Mendelian Randomization in Osteoporosis Research: the good, the bad, and the ugly [0.03%]
骨质疏松症研究中的PHEWAS、TWAS和孟德尔随机化：好坏美丑
Siwen Li,Katerina Trajanoska
Siwen Li
Purpose of review: While GWAS has identified many loci associated with bone mineral density (BMD), translating these findings into functional insights and treatments remains challenging. Post-GWAS methods such as Transcri...
Health-related Quality of Life After Vertebral Augmentation for Osteoporotic Vertebral Compression Fractures [0.03%]
骨质疏松性椎体压缩骨折经皮椎体成形术后生活质量变化特点及相关因素分析
Si Wei,Zhenjin Cai,Hao Zheng et al.
Si Wei et al.
Shunichi Yokota,Masataka Mizuno,Akio Umemoto et al.
Shunichi Yokota et al.
Advances in Imaging-Based Fracture Risk Assessment for Unlocking Latent Skeletal Fragility [0.03%]
基于成像的骨折风险评估的新进展：揭示潜在骨骼脆弱性
Yisak Kim,Sung Hye Kong
Yisak Kim
Purpose of Review: This review summarizes recent advancements in imaging-based fracture risk assessment utilizing routinely acquired clinical images. We explore how imaging-derived methodologies and deep learning techniqu...
Olivia X Jones,Kirsten D Kelly,Stephanie K Khoo et al.
Olivia X Jones et al.
Purpose of Review: This review explores the relationship between post-traumatic stress disorder (PTSD) and bone health, focusing on how chronic psychological stress influences skeletal integrity through neuroendocrine, im...
Steven Sims,Fazilet Sen,Funda Korkmaz et al.
Steven Sims et al.
Deep Learning for Analysis of Bone Marrow Adiposity: Breakthroughs from Recent Large-Scale Analyses in the UK Biobank [0.03%]
深度学习在骨髓脂肪分析中的应用：英国生物银行近期大规模分析的突破性进展
Wei Xu,Chengjia Wang,William P Cawthorn
Wei Xu
Purpose of Review: Bone marrow adipose tissue (BMAT) is a significant fat depot with distinct skeletal, haematological and metabolic roles. It increases with ageing, osteoporosis, metabolic disease, and cancer, and is eme...
Immune Checkpoint Inhibitors and Bone Health: Mechanisms, Clinical Implications, and Emerging Perspectives on Bone Fragility [0.03%]
免疫检查点抑制剂与骨骼健康：机制、临床意义及骨质疏松新观点
Muhammed Emin Bedir,Abdulhadi Cihangir Uguz,Ismail Beypinar et al.
Muhammed Emin Bedir et al.
Purpose of Review: Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, but their effects on the skeletal system, independent of the influence of bone metastases, are not fully understood. This critic...
Renee T Ormsby,Claire M Edwards
Renee T Ormsby
Purpose of review: This review highlights recent studies that investigate the metabolic reprogramming that occurs in specific types of bone metastatic cancers, including different types of breast cancer, prostate cancer a...