Osteoporotic Fractures of the Proximal Humerus: an In-Depth Review of Current Management Options [0.03%]
肱骨近端骨质疏松性骨折的治疗现状及进展
Ahmet Berkay Girgin,Ahmet Acar,Ömer Torun et al.
Ahmet Berkay Girgin et al.
Purpose of review: Proximal humerus fractures are common osteoporosis-related fractures in the elderly population. Due to these fractures, the quality of life of patients decreases significantly. This review aims to (1) d...
Intravital Microscopy of Osteocytes: A New Era in Bone Cell Biology [0.03%]
活体成像技术在骨细胞生物学中的应用：骨细胞生物学的新时代
Murtaza Wasi,Karl J Lewis
Murtaza Wasi
Purpose of review: Intravital imaging technologies have significantly transformed our understanding of osteocyte biology by enabling real-time visualization of these cells within their native microenvironment. Historicall...
Inequities Across the Spectrum of Osteoporosis Care and Post-Fracture Management in Men [0.03%]
男性骨质疏松症治疗和骨折后处理的全方位不公平性问题
Reuben Joaquim Ricardo De Almeida,Ashna Grover,Shubham Agarwal et al.
Reuben Joaquim Ricardo De Almeida et al.
Purpose of review: Sex specific differences in the determinants, occurrence, and distribution of osteoporosis and osteoporotic fractures play a pivotal role in the implementation of timely surveillance, prevention and eff...
Lyndon Mason,Chijioke Orji,Jan Szatkowski
Lyndon Mason
Purpose of review: This review evaluates current management options for managing ankle fractures in geriatric patients with osteoporosis. It addresses the challenges posed by compromised bone integrity and examines operat...
Efficacy of Osteoanabolic Agents in Type 2 Diabetes Mellitus: a Meta-analysis and Review of the Literature [0.03%]
二甲双胍对骨形成的抑制作用及促骨形成药物的效应- meta 分析和文献回顾
Rimesh Pal,Urmila Yadav,Mainak Banerjee et al.
Rimesh Pal et al.
Purpose: To synthesize evidence on the efficacy of osteoanabolic therapies (teriparatide, abaloparatide, romosozumab) in adults with type 2 diabetes mellitus (T2D), focusing on changes in bone mineral density (BMD) and fr...
Chloe J Harris,Georgia R Stewart,Abigail Foston et al.
Chloe J Harris et al.
Purpose of the Review: Cancer cell dormancy in the bone microenvironment presents a major obstacle to curative therapy across multiple cancer types. The bone harbours specialised pro-dormancy niches that promote the induc...
Masayuki Tsukasaki
Masayuki Tsukasaki
Purpose of review: The periosteum has long been recognized as being essential for bone growth and repair. More recently, its involvement has been observed in a range of pathological conditions, including cancer progressio...
New Aspects of the Pathophysiology of Diabetic Bone Fragility - Type 2 Diabetes Mellitus as a Disease of Accelerated Aging [0.03%]
糖尿病骨质脆弱的病理生理新方面-2型糖尿病作为加速衰老的疾病
Eva Maria Wölfel,Moustapha Kassem
Eva Maria Wölfel
Purpose of review: This review summarizes recent findings of the pathophysiology of bone fragility with a particular focus on type 2 diabetes (T2D). It proposes that T2D is a condition of accelerated aging, highlighting m...
Leveraging Proteomics and Proteogenomics for Understanding Osteoporosis and Other Musculoskeletal Diseases [0.03%]
利用蛋白质组学和蛋白质基因组学理解骨质疏松症及其他肌肉骨骼疾病
Masashi Hasebe,Chen-Yang Su,Douglas P Kiel et al.
Masashi Hasebe et al.
Purpose of review: Osteoporosis and musculoskeletal diseases, including osteoarthritis and sarcopenia, contribute substantially to global morbidity and healthcare costs. This review explores how proteogenomics integrates ...
Hypophosphatasia and Type 1 Diabetes: A Pilot Study and Review of Literature [0.03%]
低磷酸酶症与1型糖尿病：一项初步研究及文献回顾
Zunera Tariq,Jake P Tinsley,Dana Carpenter et al.
Zunera Tariq et al.
Purpose of review: Hypophosphatasia (HPP) and type 1 diabetes (T1D) are both associated with low bone turnover and increased fracture risk. In this review, our objectives were to (a) discuss results of our pilot study aim...