Valeria Bertani,Lucia Minoli,Anna de Battisti et al.
Valeria Bertani et al.
The SDRG rat, characterized by a Sprague-Dawley (SD) genetic background with deletion of Rag1 and Il2rg genes, has deficiencies in B, T, and natural killer (NK) cells, making it a valuable model for preclinical applications such as tissue t...
Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs [0.03%]
人CD34阳性造血干细胞植入NSG小鼠的病理学特征:对癌症免疫治疗药物安全性评估的意义
Anna Maria Giusti,Johannes Sam,Sara Colombetti et al.
Anna Maria Giusti et al.
Humanized mice engrafted with human CD34+ hematopoietic stem cells (HSCs) are invaluable models for the preclinical evaluation of cancer immunotherapy drugs, helping to bridge the gap between in vitro studies and clinical trials. However, t...
Marietta V Barro,Qian J Chen,Anibal G Armien et al.
Marietta V Barro et al.
Female Hsd:Athymic nude-Foxn1nu sentinel mice spontaneously develop a life-limiting protein-losing nephropathy. We aimed to characterize this disease and identify risk factors. Affected mice presented with anasarca and pale tan, irregularly...
Hydranencephaly and porencephaly predominated among neuropathologic findings in stillborn and neonatal piglets during the first major outbreak of Japanese encephalitis in Australia [0.03%]
猪水疱病流行的早期阶段日本脑炎病毒在澳大利亚Still-born和新生儿猪体内的神经病理学发现以水瘤和脑室周围脑质缺损为主
Willy W Suen,Anne Jordan,Leah K Manning et al.
Willy W Suen et al.
In 2022, piggeries in southeastern Australia experienced an increase in reproductive losses and occasional neurologic disease in neonates with up to 100% mortality in some litters. Molecular testing identified a genotype IV Japanese encepha...
Application of confocal laser microscopy and its feasibility in routine diagnosis of surgical biopsy specimens [0.03%]
共聚焦激光显微镜在手术切除标本病理诊断中的应用及可行性研究
Yea Ji Jeong,Gabrielle S Fontes,Laura E Selmic et al.
Yea Ji Jeong et al.
Handheld confocal laser endomicroscopy (CLE) enables an instantaneous assessment of the cellular morphology of different tumor types and margin assessment ex vivo. Here, we describe the correlation between CLE images and histology and the f...
World-class educational content and award-winning presentations await you at the 2025 ACVP annual meeting [0.03%]
2025年ACVP年度会议将为您提供世界级的教育内容和屡获殊荣的演讲
Katharine Webster
Katharine Webster
Austwickia chelonae-associated cutaneous and plastron lesions in Chinese stripe-necked turtles (Mauremys sinensis) [0.03%]
与中国条纹颈龟(Austwickia chinensis)相关的Austwickia chelonae皮肤和腹甲病变
Chia-Yu Hsieh,Shang-Ting Wu,Yung-Ling Chang et al.
Chia-Yu Hsieh et al.
Between June 2020 and January 2022, 10 cases of shell rot with unknown etiology were investigated in Chinese stripe-necked turtles (Mauremys sinensis) from aquaculture farms in southern Taiwan. Histology revealed gram-positive filamentous b...
Cardiac autolysosome dysfunction associated with reverse osmosis water in a breeding colony of prairie voles (Microtus ochrogaster) [0.03%]
与反渗透水相关的草原田鼠(Microtus ochrogaster)繁殖群的心肌自噬溶酶体功能障碍
Jimmy Guan,Dahihm Kim,Glenn Jackson et al.
Jimmy Guan et al.
Prairie voles (Microtus ochrogaster) from 1 of the 3 laboratory animal facilities experienced increased unexpected deaths with no clinical signs. There was a total of 30 deaths in the affected facility and 16 deaths in the other 2 unaffecte...
Pathogenicity of the novel antigenic variant infectious bursal disease virus B2977CE2C3 isolated in Japan: Histological analysis of experimentally infected chickens [0.03%]
日本新型抗原变异传染性法氏囊病病毒B2977CE2C3株的致病力分析:病理组织学变化研究
Soma Ito,Mari Takahashi,Kazumoto Shibuya et al.
Soma Ito et al.
Infectious bursal disease (IBD) is an immunosuppressive disease caused by the IBD virus (IBDV), leading to substantial economic losses in the poultry industry. Recently, a novel antigenic variant IBDV (nvIBDV) has emerged in China and sprea...