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期刊名:Molecular pharmaceutics

缩写:MOL PHARMACEUT

ISSN:1543-8384

e-ISSN:1543-8392

IF/分区:4.9/Q1

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共收录本刊相关文章索引7262
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Han Gao,Zhao-Lin Ding,Jun Ouyang et al. Han Gao et al.
Driven by the evolving demands of modern pharmaceutical industry, high-concentration monoclonal antibody formulations (HCMFs) have emerged as a central research hotspot in biopharmaceutical development, attributable to their merits such as ...
N S Krishna Kumar,Zhiyi Lin,Cole W Tower et al. N S Krishna Kumar et al.
Residual water in freeze-dried protein formulations plays a critical role in molecular relaxation behavior. In a previous study (Kumar et al., Mol Pharmaceutics 2025, 22, 4125-4136), we examined the impact of sucrose concentration on native...
Xiaoqing Zhuang,Jenni Virta,Negar A Samani et al. Xiaoqing Zhuang et al.
L-Lactate is a key substrate in energy metabolism and a potential biomarker for cancer and metabolic disorders. We developed an enantiomerically pure positron emission tomography (PET) tracer, (R)-[18F]fluorolactate, to mimic natural L-lact...
Masayuki Munekane,Kazuki Matsunaga,Miki Ozaki et al. Masayuki Munekane et al.
In Auger electron therapy, the effective delivery of Auger electron-emitting radionuclides to the nuclei of cancer cells is essential for achieving high therapeutic efficacy. In this study, we developed a novel strategy that combined thermo...
Vida Nazar,Lincoln Paul Buxton,Sui Jiang et al. Vida Nazar et al.
The intracellular delivery of full-length antibodies offers substantial therapeutic potential but remains limited by poor cellular uptake, extracellular degradation, and inefficient encapsulation strategies. Here, we report a noninvasive, s...
Xin Yao,Mengqi Yu,Fei Chen et al. Xin Yao et al.
Pharmaceutical salts are commonly used to enhance the bioavailability of poorly water-soluble drugs. The maximum solubility in water and the physical stability of a salt are closely linked to its pHmax, the pH at which both the free form (a...
Sun Mi Park,Tae Sup Lee,Jieun Lee et al. Sun Mi Park et al.
Necroptosis is a regulated, pro-inflammatory form of programmed cell death implicated in degenerative and inflammatory diseases, with RIPK1 acting as a key upstream regulator. However, the utility of existing RIPK1 PET radiotracers, as well...
Aiai Wang,Hui Xu,Zhihui Xin et al. Aiai Wang et al.
Porphyrin bimetallic metal-organic frameworks (BMOFs) have promising applications in photodynamic therapy (PDT) and chemodynamic therapy (CDT) for tumor therapy. However, their therapeutic effect is restricted by the insufficient reactive o...