Mei Dai,Qin Jiang,Danhua Zhang et al.
Mei Dai et al.
Myosin IB (MYO1B), a member of the type I myosin family, is overexpressed in various tumor tissues. MYO1B facilitates tumor progression by regulating cellular proliferation, migration, and the epithelial-mesenchymal transition (EMT). Howeve...
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression [0.03%]
RYK沉默修饰的骨髓来源间充质干细胞抑制胃癌进展
Yongan Fu,Zongda Cai,Yangqiang Wang et al.
Yongan Fu et al.
Gastric cancer (GC) is a prevalent malignant tumor threatening human health. This study aimed to explore the potential mechanism of receptor-like tyrosine kinase (RYK) silencing-modified bone marrow-derived mesenchymal stem cells (BMSCs) in...
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma [0.03%]
卡博替尼通过激活TFEB介导的自噬在肝癌中发挥抗肿瘤作用
Cheng Chen,Yongjie Hu,Chenggang Zhang et al.
Cheng Chen et al.
Autophagy signaling plays a crucial yet complex role in hepatocellular carcinoma (HCC), influencing tumor progression and treatment response. Cabozantinib is an orally administered multi-kinase inhibitor used in the treatment of various adv...
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish (Danio rerio) cell models [0.03%]
基于斑马鱼细胞模型的石墨烯氧化物和石墨碳氮化物纳米颗粒的综合评估：从合成到体外生物影响
Baskaran Valarmathi,Sivaraj Mithra,Seepoo Abdul Majeed et al.
Baskaran Valarmathi et al.
Graphene and its derivatives have been increasingly explored for various biomedical applications. Despite their promising potential, the accelerated development and integration of these materials in medical technologies have raised importan...
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket Acheta domesticus [0.03%]
家蟋蟀胚胎细胞的长期培养体系及细胞系建立
Stephen A Schwartz,Sophia M Letcher,Noah Novick et al.
Stephen A Schwartz et al.
Insect cell culture has become foundational for many areas of research and biotechnological innovation, yet major taxonomic gaps persist, particularly among orthopteran species. Here, we report the isolation and long-term maintenance of pri...
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy [0.03%]
绞股蓝皂苷F1通过激活AMPK/PGC-1α信号通路和自噬改善非酒精性脂肪肝病
Wenjiao Xie,Yun Lv,Zhixian Zhou et al.
Wenjiao Xie et al.
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases globally, and currently, there is a lack of specific effective drugs. Ginsenoside F1 (Gf1) is the main active ingredient of the traditional Cahine...
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer [0.03%]
升高的膀胱内压促进膀胱癌荷瘤小鼠循环肿瘤细胞释放
Ling Yi,Qing Chen,Min Zeng et al.
Ling Yi et al.
Elevated intravesical pressure during transurethral resection of bladder tumor (TURBT) is hypothesized to facilitate the release of circulating tumor cells (CTCs), potentially increasing the risk of hematogenous metastasis. However, the cau...
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2 [0.03%]
人乳牙干细胞中miR-3614-5p通过靶向溶血磷脂酸受体2抑制内皮分化和血管生成
Yiming Chen,Li Zhang,Jie Zhang et al.
Yiming Chen et al.
The contribution of microRNAs (miRNAs) to the endothelial differentiation of stem cells from human exfoliated deciduous teeth (SHED) remains largely unclear. This study sought to uncover novel miRNAs implicated in this process. SHED were ob...
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis [0.03%]
LPS活化牙龈成纤维细胞通过CXCL12/CXCR4-Snail2-上皮间质转化轴促进胃癌细胞迁移的机制研究
Tongbin Liu,Qi Tang,Min Liu et al.
Tongbin Liu et al.
The objective of this article is to explore the influence and process by which periodontitis affects the metastasis of gastric cancer cells. Human gingival fibroblasts (HGFs) underwent stimulation with lipopolysaccharide (LPS), and ELISA wa...