Overexpression of MEOX2 inhibits breast cancer cell metastasis by targeting oxidative stress-induced RGS5 [0.03%]
MEOX2过表达通过靶向氧化应激诱导的RGS5抑制乳腺癌细胞转移
Yujun Tang,Jie Luo,Bin Jiang et al.
Yujun Tang et al.
This study aimed to investigate the role of mesenchymal homeobox 2 (MEOX2) on breast cancer cell metastasis and its underlying mechanism. Overexpression of MEOX2 in human lymphatic endothelial cell (HLEC) lines was established to assess the...
Non-animal testing of Iranian enterotoxemia vaccine: cell culture assay for Clostridium perfringens epsilon toxin [0.03%]
伊朗产肠毒素疫苗的无动物检测方法：肉毒杆菌ε毒素细胞培养检验法
Anahita Emadi,Lida Abdolmohammadi Khiav,Sina Soleimani et al.
Anahita Emadi et al.
Epsilon toxin produced by Clostridium perfringens type D is the third most potent clostridial toxin. It causes enterotoxemia in sheep and lambs. The clostridial vaccine has been used against clostridial disease, and its efficacy is evaluate...
Ginsenoside Rb1 inhibits M1 macrophages-induced IGFBP2-mediated endothelial-mesenchymal transition to alleviate myocardial fibrosis in mice with chronic heart failure [0.03%]
Ginsenoside Rb1通过抑制M1巨噬细胞诱导的IGFBP2介导的内皮间质转化来缓解慢性心力衰竭小鼠的心肌纤维化
Yang Jiang,Qi Zhao,Ting Zhang et al.
Yang Jiang et al.
Ginsenoside Rb1 ameliorates renal fibrosis, yet its effects on myocardial fibrosis (MF) remain unclear. In this study, we aimed to explore the role of ginsenoside Rb1 in chronic heart failure (CHF) and MF. To explore the correlation between...
LncRNA TDRG1 facilitates high glucose-induced retinal microvascular endothelial cell injury via miR-7-5p/G3BP2 [0.03%]
长链非编码RNA TDRG1通过miR-7-5p/G3BP2促进高糖诱导的视网膜微血管内皮细胞损伤
Shuying Xie,Zehong Liu,Ting Luo et al.
Shuying Xie et al.
This study explores the mechanism of lncRNA TDRG1 in high glucose (HG)-induced human retinal microvascular endothelial cell (hRMEC) injury. hRMECs were cultured in HG medium, followed by the detection of cell viability, proliferation, migra...
Grb2/Sos1 signaling regulates the number of reserve cells in C2C12 cell culture [0.03%]
Grb2/Sos1信号调节C2C12细胞培养中的储备细胞数量
Yosuke Nagata,Hiroto Iitsuka,Tomoharu Hagiwara
Yosuke Nagata
Skeletal muscle regeneration depends on satellite cells that maintain tissue homeostasis through self-renewal and the production of myoblasts that differentiate into mature myofibers. Dysregulation of these processes can lead to muscle dege...
MiR-21-5p promotes RPE cell necroptosis by targeting Peli1 in a rat model of AMD [0.03%]
MiR-21-5p通过靶向Peli1促进AMD大鼠模型视网膜色素上皮细胞坏死性凋亡
Yishun Shu,Ziwen Li,Tianyi Zong et al.
Yishun Shu et al.
Nonexudative age-related macular degeneration (dry AMD) is characterized by the progressive degeneration of retinal pigment epithelial (RPE) cells and photoreceptors, resulting in central vision loss. The disease is primarily marked by the ...
Efficient cryopreservation of Antillean manatee skin-derived somatic cells via reduced intracellular cryoprotectant concentration [0.03%]
通过降低细胞内冷冻保护剂浓度高效冻存加勒比海海洋哺乳动物皮肤来源的体细胞
Luanna Lorenna Vieira Rodrigues,Lhara Ricarliany Medeiros de Oliveira,Yasmin Beatriz França Moura et al.
Luanna Lorenna Vieira Rodrigues et al.
The declining population of the Antillean manatees has prompted interest in developing conservation strategies, including somatic cell cryopreservation. However, the type and concentration of intracellular cryoprotectant agents (CPAs) are l...
Wound healing properties of Biginelli scaffolds in Tilapia gill cell line: an in vitro analysis and computational approaches [0.03%]
基于Tilapia鱼鳃细胞系的大黄素支架伤口愈合性能的体外分析及计算方法研究
Noorudeen Paringamalai,Syed Tajudeen Syed Ameen,Abdul Matheen Ibrahim et al.
Noorudeen Paringamalai et al.
The skin is a vital organ that regulates the temperature, nutrient absorption, and perception of sensations. Wound healing is a complex biological process in multicellular systems that consists of four key phases: hemostasis, inflammation, ...
PKCβ expression contributes to M1 macrophage-induced impairment in the osteogenic differentiation of periodontal ligament stem cells [0.03%]
PKCβ表达通过M1型巨噬细胞极化抑制牙周韧带干细胞成骨分化
Yang Liu,Zhaocen Liu
Yang Liu
Protein kinase Cβ (PRKCB) is expressed in THP-1 cells and has been found upregulated in periodontitis. Exploring the specific molecular mechanisms that promote the osteogenic differentiation of human periodontal ligament stem cells (hPDLSC...
miR- 34c- 5p targets ROCK1 expression to inhibit kidney injury in diabetic nephropathy rats through MAPK/ERK signaling pathway [0.03%]
miR-34c-5p通过MAPK/ERK信号通路靶向ROCK1表达抑制糖尿病肾病大鼠肾脏损伤
HuaJuan Wei,Ye Li,HongDe Liu et al.
HuaJuan Wei et al.
This study was to investigate the mechanism of miR- 34c- 5p in alleviating kidney injury in diabetic nephropathy (DN) rats by targeting ROCK1 and MAPK/ERK signaling pathway. The rat model of DN was established and fasting blood glucose, 24-...