Developmental toxicity research of ginsenoside Rb1 using a whole mouse embryo culture model [0.03%]
应用整体小鼠胚胎培养模型研究人参皂苷Rb1的发育毒性
Peng Liu,Yajun Xu,Huijun Yin et al.
Peng Liu et al.
Background: Ginseng has been widely used around the world for many years. Knowledge is limited, however, on its effects on embryonic development. Methods:...
Center for the evaluation of risks to human reproduction--the first five years [0.03%]
人类生殖风险评估中心——最初的五年工作经验
Gloria D Jahnke,Annette R Iannucci,Anthony R Scialli et al.
Gloria D Jahnke et al.
The National Toxicology Program (NTP) Center for the Evaluation of Risks to Human Reproduction (NTP-CERHR) was established by the NTP and the National Institute of Environmental Health Sciences (NIEHS) in 1998 to address the impact of chemi...
National Toxicology Program Center for the Evaluation of Risks to Human Reproduction: guidelines for CERHR expert panel members [0.03%]
美国毒性程序人类生殖风险评估中心：CERHR专家小组成员准则
Michael D Shelby;Center for the Evaluation of Risks to Human Reproduction Expert Panel
Michael D Shelby;Center for the Evaluation of Risks to Human Reproduction Expert Panel
Comment on developmental toxicity evaluation of butylparaben in Sprague-Dawley rats [0.03%]
评价丁基对羟基苯甲酸酯Sprague-Dawley大鼠发育毒性试验的几点思考
Philip W Harvey
Philip W Harvey
NTP-CERHR expert panel report on the reproductive and developmental toxicity of acrylamide [0.03%]
NTP-CERHR专家小组关于丙烯酰胺生殖及发育毒性的报告
Jeanne Manson,Michael J Brabec,Judy Buelke-Sam et al.
Jeanne Manson et al.
Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. II. Histopathological features of teratological anomalies induced in fetuses [0.03%]
赭曲霉毒素A和黄曲霉毒素B1联合暴露对大鼠胚胎发育毒性的致畸作用及病理特征研究(英文)
P B Wangikar,P Dwivedi,A K Sharma et al.
P B Wangikar et al.
The histopathological features of various abnormalities induced by different doses of ochratoxin A (OA), aflatoxin B1 (AFB1), and their combination in rat fetuses were studied. The pregnant Wistar rats were orally treated during 6-15 gestat...
Developmental toxicity evaluation of trimethylolpropane caprylate caprate in Sprague-Dawley rats [0.03%]
三羟丙基硬脂酸辛癸酸酯对大鼠发育毒性评估研究
Charles Azuka,George P Daston
Charles Azuka
The developmental toxicity potential of trimethylolpropane caprylate caproate (TMPCC, CAS no. 11138-60-6) was evaluated in rats. Sprague-Dawley rats were administered TMPCC in a corn oil suspension dermally at dose levels of 0, 200, 600, or...
Effects of an antisense oligonucleotide inhibitor of human ICAM-1 on fetal development in rabbits [0.03%]
人ICAM-1抗义寡核苷酸抑制剂对兔胎儿发育的影响
Scott P Henry,Kevin H Denny,Mike V Templin et al.
Scott P Henry et al.
The potential for reproductive toxicity of an antisense oligonucleotide designed to inhibit ICAM-1 was evaluated as part of the safety assessment for this compound. The human active ICAM-1 inhibitor (ISIS 2302) is not pharmacologically acti...
Effects of human and murine antisense oligonucleotide inhibitors of ICAM-1 on reproductive performance, fetal development, and post-natal development in mice [0.03%]
人和小鼠ICAM-1反义寡核苷酸抑制剂对小鼠生殖机能、胎仔发育及产后影响的研究
Scott P Henry,Kevin H Denny,Mike V Templin et al.
Scott P Henry et al.
The potential for reproductive toxicity of an antisense oligonucleotide designed to inhibit ICAM-1 was evaluated as part of the safety assessment for this compound. Since antisense compounds are often specific to the species in which they a...
Effect in rats of simultaneous prenatal exposure to ochratoxin A and aflatoxin B1. I. Maternal toxicity and fetal malformations [0.03%]
赭曲霉毒素A和黄曲霉素B1联合暴露对大鼠胎仔的影响Ⅰ——母体毒性及致畸作用
P B Wangikar,P Dwivedi,Neeraj Sinha
P B Wangikar
Ochratoxin A (OA) and Aflatoxin B1 (AFB1), the food borne mycotoxins are produced by several fungal species of the genera Aspergillus and Penicillium. To determine the teratogenic effects, these mycotoxins were administered orally either in...