Efficacy of Methocarbamol for Acute Pain Management in Young Adults With Traumatic Rib Fractures [0.03%]
甲喹酮对创伤性肋骨骨折年轻成人急性疼痛管理的有效性
Lindsay P Deloney,Melanie Smith Condeni,Cassandra Carter et al.
Lindsay P Deloney et al.
Background: Rib fractures account for more than one-third of blunt thoracic injuries and are associated with serious complications. Use of nonopioid adjunctive agents such as methocarbamol for pain control has increased c...
Observational Study
The Annals of pharmacotherapy. 2021 Jun;55(6):705-710. DOI:10.1177/1060028020964796 2021
An Evaluation of Continuous Infusion Rocuronium for Sustained Neuromuscular Blockade in Critically Ill Adults [0.03%]
连续输注罗库溴铵在重症成人持续神经肌肉阻滞中的评估研究
Lara M Groetzinger,Aaron T Hutchins,Ryan M Rivosecchi
Lara M Groetzinger
Background: Recent medication shortages of the neuromuscular blocking agent (NMBA) cisatracurium have forced the prescribing of aminosteroidal agents such as rocuronium. There are limited data on the use and dosing of con...
Safety of Single-Dose Oral Cefixime, Intramuscular Ceftriaxone, or Intramuscular Gentamicin for the Treatment of Gonorrhea: A Systematic Review and Meta-analysis [0.03%]
单剂量口服塞克硝眯，肌注头孢三嗪或肌注庆大霉素治疗淋病的安全性：系统评价和荟萃分析
Jacob Dresser,Kyle John Wilby
Jacob Dresser
Objective: To compare the incidence and types of adverse effects between 3 recommended treatment options for gonorrhea and to compare the incidence of injection site pain between single-dose intramuscular ceftriaxone and ...
Comment: Assessment of Acute Kidney Injury in Neurologically Injured Patients Receiving Hypertonic Sodium Chloride: Does Chloride Load Matter? [0.03%]
评论：评估神经损伤患者接受高渗氯化钠后的急性肾损伤：氯负荷重要吗？
Gildas Gueret,Pascale Le Maguet,Pierre Lefebvre et al.
Gildas Gueret et al.
Sustained Virologic Response of Patients Hospitalized Compared With Those Not Hospitalized During Treatment for Hepatitis C Virus With Direct-Acting Antivirals [0.03%]
直接抗病毒治疗住院和非住院丙肝患者的持续病毒学应答率对比研究
Anthony J Gentene,Allison M Bell,Alicia Pence et al.
Anthony J Gentene et al.
Background: Direct-acting antivirals (DAAs) for treatment of hepatitis C virus (HCV) have resulted in great success through high attainment of sustained virologic response (SVR). Risk factors for DAA treatment failure are...
Comparative Study
The Annals of pharmacotherapy. 2021 May;55(5):565-574. DOI:10.1177/1060028020964117 2021
Intravenous Zanamivir: A Viable Option for Critically Ill Patients With Influenza [0.03%]
静脉zanamivir：流感重症患者的可选方案
Douglas Slain
Douglas Slain
Objective: To review the pharmacology, clinical trial data, and clinical implications for the intravenous formulation of zanamivir. Data sources: ...
Impact of Hyperoncotic Albumin on Duration of Vasopressor Support in Septic Shock: A Propensity Score-Matched Analysis [0.03%]
白蛋白对感染性休克血管加压素支持时间的影响：一种倾向评分匹配分析方法
Alexander H Flannery,Gary D Owen,Angel Coz et al.
Alexander H Flannery et al.
Background: While albumin has not been shown to reduce mortality in sepsis and septic shock, a tertiary analysis of a large trial suggested that it may reduce the duration of vasopressor use in septic shock. ...
Novel Therapies in Acute Migraine Management: Small-Molecule Calcitonin Gene-Receptor Antagonists and Serotonin 1F Receptor Agonist [0.03%]
急性偏头痛治疗新进展：降钙素基因受体拮抗剂和五羟色胺1F型受体激动剂的小分子疗法
Kayla Rena Joyner,Kelsey Woods Morgan
Kayla Rena Joyner
Objective: To review the efficacy, safety, and cost of 3 newly approved agents-ubrogepant, lasmiditan, and rimegepant-representing 2 therapeutic classes, calcitonin gene-related peptide (CGRP) receptor antagonist and sero...
Apixaban Levels Detected in a Patient 10 Days From Last Known Dose While Experiencing Acute on Chronic Kidney Disease [0.03%]
急性慢性肾脏病患者在最后一次已知剂量给药后10天内检测到的阿哌沙班水平
Zachary S Robinson,Nicole G Harper
Zachary S Robinson