Safety Evaluation of Weight-Tiered, Anti-Xa-Guided Versus Fixed-Dose Enoxaparin Prophylaxis in Traumatic IntraCranial Hemorrhage (SAFE-ICH): A Retrospective Cohort Study [0.03%]
针对创伤性脑内出血的体重分层、抗Xa指导与固定剂量依诺肝素预防的评估（安全ICH研究）：一项回顾性队列研究
Brittany Michele Curran,Carolyn D Philpott,Madeline Foertsch et al.
Brittany Michele Curran et al.
Background: Traumatic intracranial hemorrhage (tICH) increases venous thromboembolism (VTE) risk counterbalanced by a life-threatening bleed in a critical organ space. Weight-tiered and anti-Xa-guided enoxaparin dosing ma...
Comparative Analysis of Fixed Versus Variable Rates of Regional Citrate Anticoagulation in Critically Ill Adult Patients on Continuous Kidney Replacement Therapy [0.03%]
连续肾脏替代疗法患者固定剂量与变化剂量区域肝素抗凝的比较分析研究
Nhi TranHuynh,Jenna Holzhausen,Lisa Hall Zimmerman
Nhi TranHuynh
Background: The Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline recommends regional citrate anticoagulation during continuous kidney replacement therapy (CKRT) to prolong circuit lifespan. Lim...
Predictive Value of Methicillin-Resistant Staphylococcus aureus Nasal Swab PCR Assay for MRSA Pneumonia in Critically Ill Stroke Patients [0.03%]
脑卒中重症患者鼻拭子检测金黄色葡萄球菌耐甲氧西林基因对预测呼吸机相关性耐甲氧西林金黄色葡萄球菌肺炎的价值研究
Mikayla K Gerdes,Jacob P Counts,Hera A Kamdar et al.
Mikayla K Gerdes et al.
Background: Ischemic and hemorrhagic strokes are associated with significant morbidity and mortality, with secondary complications such as stroke-associated pneumonia (SAP) contributing to increased mortality rates. Methi...
Duration of Concurrent Oxycodone and Selective Serotonin Reuptake Inhibitors Use and the Risk of Opioid Overdose [0.03%]
共用氧可酮和选择性血清素回收抑制剂的风险与阿片类药物过量持续时间的关系
Chijioke Okeke,Olajumoke Olateju,Ismaeel Yunusa et al.
Chijioke Okeke et al.
Background: Concurrent use of oxycodone and strong cytochrome P450 2D6 (CYP2D6)-inhibiting selective serotonin reuptake inhibitors (SSRIs), specifically paroxetine and fluoxetine, is associated with the risk of opioid ove...
Elevated Risk of Asthma Among Proton Pump Inhibitor Users: Evidence From Meta-Analysis [0.03%]
质子泵抑制剂使用者的哮喘高危倾向：Meta分析证据显示
Sayed Aliul Hasan Abdi,Shabihul Fatma Sayed,Sumathi Nagarajan
Sayed Aliul Hasan Abdi
Retrospective, Single-Center Cohort Study of Bivalirudin Compared to Unfractionated Heparin in Patients Receiving Extracorporeal Membrane Oxygenation [0.03%]
回顾性单中心队列研究：体外膜氧合患者使用比伐卢定与普通肝素的比较
Thomas Lofy,Janelle Juul,Brittney Duewell et al.
Thomas Lofy et al.
Background: Extracorporeal membrane oxygenation (ECMO), a form of temporary mechanical circulatory support, causes a prothrombotic state due to activation of inflammatory processes via exposure of blood to the circuit. Sy...
Impact of Substantial Weight Loss on Digoxin Intoxication During Long-term Therapy [0.03%]
显著体重减轻对长期地高辛治疗的影响
Hirokazu Nakayama,Tsuyoshi Shiga,Masayo Tanaka
Hirokazu Nakayama
Background: Despite numerous safety studies on digoxin, the association of substantial body weight loss with the development of digoxin intoxication and the transition of risk factors over time in patients on long-term di...
Efficacy of Oxycodone Combined With Thoracic Paravertebral Nerve Block for Postoperative Analgesia in Esophageal Cancer Surgery: A Retrospective Study [0.03%]
羟考酮复合胸段椎旁神经阻滞用于食管癌术后镇痛的疗效分析：一项回顾性研究
Weiwei Li,Fujun Wang,Hangwei Zhou et al.
Weiwei Li et al.
Background: Thoracoscopic esophagectomy for esophageal cancer often results in substantial postoperative pain, which may impair recovery and increase the risk of complications. Effective and well-tolerated analgesia is es...
Acoramidis: A New Transthyretin Stabilizer for Transthyretin Amyloid Cardiomyopathy [0.03%]
新型转运蛋白稳定剂乙基立德欣治疗转甲状腺素淀粉样变性心肌病
Taylor Clark,Rachel Lucas,Azadeh Nasuhidehnavi et al.
Taylor Clark et al.
Objective: The objective of the study was to review acoramidis, a new transthyretin stabilizer, for treatment of transthyretin amyloid cardiomyopathy by means of pharmacology, efficacy, and safety. ...
Association of CYP2C19 Phenotype on Historical Medication Prescribing for Gastroesophageal Reflux Disease [0.03%]
CYP2C19表型对既往反流病药物处方的关联性研究
Jennifer Cole,Leela Kodali,Jennifer Stark et al.
Jennifer Cole et al.
Introduction: While consensus guidelines exist for phenotype-guided proton pump inhibitor (PPI) dosing in Helicobacter pylori infection, the impact in gastroesophageal reflux disease (GERD) treatment in a real-world setti...