Obecabtagene Autoleucel in Relapsed/Refractory B-ALL: A Critical Review of Clinical Efficacy and Safety [0.03%]
奥贝妥珠单抗自体T细胞治疗复发/难治B-ALL的临床疗效及安全性批判性分析
Emily Hu,Sarah Johnson,Timber Abinsay et al.
Emily Hu et al.
Objective: This article reviews the published data encompassing the development, pharmacology, efficacy, and safety of obecabtagene autoleucel, summarizing data from pivotal clinical studies and clinical relevance in the ...
Bulevirtide (Hepcludex) for Chronic Hepatitis Delta: A Milestone Achievement Demanding Real-World Evaluation [0.03%]
布列維迪姆肽（赫普克路德）治療慢性delta肝炎：實現里程碑成就並進行現實世界評估
Aun Muhammad Shoro,Sufwan Ullah Khan
Aun Muhammad Shoro
Lauren Linenfelser,Melissa Lipari,Pramodini Kale-Pradhan
Lauren Linenfelser
Objective: To review the pharmacology, efficacy, and safety of subcutaneous depemokimab-ulaa as add-on therapy in the treatment of severe eosinophilic asthma. ...
Impact of Population-Specific Phenytoin Correction Factors on Estimation of Free Phenytoin Concentrations in a Community Teaching Hospital [0.03%]
特定人群苯妥英纠正因子对社区教学医院游离苯妥英浓度估计的影响
Abriana M Palumbo,Andrew Soliman,Kaysey Cloud et al.
Abriana M Palumbo et al.
Background: Phenytoin is a highly protein-bound medication and monitored due to its narrow therapeutic range. Free phenytoin serum concentratinos (fPHTm) are not readily available in many institutions. ...
Functional vs Structural Renal Outcomes of SGLT2 Inhibitors in Autosomal Dominant Polycystic Kidney Disease: A Systematic Review of Preclinical and Clinical Evidence [0.03%]
SGLT2抑制剂在常染色体显性多囊肾病的肾脏功能和结构转归：系统综述和临床证据分析
Faiza Naeem,Siew Chin Ong,Muhammad Daoud Butt et al.
Faiza Naeem et al.
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) provide significant renoprotection in chronic kidney disease, but their efficacy in autosomal dominant polycystic kidney disease (ADPKD) remains unclear. ...
Clinical Evaluation of Bysanti: A New Atypical Antipsychotic for Schizophrenia and Bipolar I Disorder [0.03%]
Bysanti（瑞派拉得）的临床评价：一种新的非典型抗精神病药物在精神分裂症和I型双相情感障碍中的疗效及安全性评估
Bradley Phillips,Melanie Horta,Nicole Santini et al.
Bradley Phillips et al.
Objective: To review the pharmacology, pharmacokinetics, efficacy, safety, and clinical role of milsaperidone (Bysanti), a newly approved atypical antipsychotic for schizophrenia and acute bipolar I disorder. ...
Impact on Vulnerable Populations After Discontinuation of Continuous Glucose Monitoring in Patients With Type 2 Diabetes [0.03%]
连续血糖监测在2型糖尿病患者中停用后的对弱势人群的影响
Bernadette Asias-Dinh,Natalie Rosario,Kevin Garey et al.
Bernadette Asias-Dinh et al.
Background: Continuous glucose monitoring (CGM) reinforces positive nonpharmacologic behaviors and optimizes pharmacotherapy. Long-term CGM may be financially unsustainable in vulnerable populations, but data on durabilit...
Evaluation of Terlipressin and In-Hospital Mortality in the Treatment of Hepatorenal Syndrome-Acute Kidney Injury (HRS-AKI) [0.03%]
特利加压素治疗肝肾综合征-急性肾损伤(HRS-AKI)的疗效及院内死亡率评估
Haley N Johnson,Paul A Juang
Haley N Johnson
Background: Terlipressin is a synthetic vasopressin analogue that is indicated for the treatment of hepatorenal syndrome-acute kidney injury (HRS-AKI) to improve kidney function and haemodynamics. Despite its previous app...