Characterization of Pharmacogenetic Information in Food and Drug Administration Drug Labeling and the Table of Pharmacogenetic Associations [0.03%]
美国食品药品监督管理局药物说明书和药理基因关联表中的药理基因信息特征分析
Christine M Cheng,Thomas W So,Jeff L Bubp
Christine M Cheng
Background: The US Food and Drug Administration (FDA) recommends using only FDA-reviewed pharmacogenetic information to make prescribing decisions based on genetic test results. Such information is available in drug label...
Preventive Effect of Probiotics on Ventilator-Associated Pneumonia: A Meta-analysis of 2428 Patients [0.03%]
益生菌预防呼吸机相关性肺炎的疗效 meta 分析：一项基于2428例患者的系统综述和 meta 分析
Ting Ji,Xingxing Zhu,Futai Shang et al.
Ting Ji et al.
Background: Researchers had contradictory conclusions about the role of probiotics in preventing ventilator-associated pneumonia (VAP), which has led to the controversial use of probiotics in mechanically ventilated patie...
Alexa Pass,Damian Bialonczyk,Elaine Chiquette et al.
Alexa Pass et al.
Objective: To describe the mechanism, clinical trial data, adverse effects, and potential role in therapy of an oral superabsorbent hydrogel (OSH) for weight management. ...
Lurbinectedin: A New Treatment Option for Relapsed/Refractory Small-Cell Lung Cancer [0.03%]
lurbinectedin：复发/难治性小细胞肺癌的新治疗选择
Lauren T Shinn,Katrina A Vo,David J Reeves
Lauren T Shinn
Objective: To assess the clinical application of lurbinectedin and its role in the therapy of small-cell lung cancer (SCLC). Data sources: ...
Bioidentical Oral 17β-Estradiol and Progesterone for the Treatment of Moderate to Severe Vasomotor Symptoms of Menopause [0.03%]
用于治疗中度至重度绝经期血管舒缩症状的生物同种雌二醇和孕酮口服疗法
C Brock Woodis,Emily Ghassemi,Amber N McLendon
C Brock Woodis
Objective: To review the efficacy, safety, and available literature regarding the novel combination bioidentical product Bijuva, or 17β-estradiol/progesterone (17β-E/P), for the treatment of moderate to severe menopausa...
Xiaoyan Huang,Jing Xue,Min Gao et al.
Xiaoyan Huang et al.
Objective: To review medical management of inoperable malignant bowel obstruction. Data sources: A literature review using PubMed and M...
23.4% Sodium Chloride Versus Mannitol for the Reduction of Intracranial Pressure in Patients With Traumatic Brain Injury: A Single-Center Retrospective Cohort Study [0.03%]
高渗盐水与甘露醇降低创伤性脑损伤患者颅内压的疗效比较：单中心回顾性队列研究
Hayley A Tatro,James C McMillen,Leslie A Hamilton et al.
Hayley A Tatro et al.
Background: Intermittent doses of mannitol or hypertonic saline are recommended to treat elevated intracranial pressure (ICP). However, it is unclear if one agent is more effective than the other. Previous studies have co...
Comparison of Vasopressor Duration in Septic Shock Patients With and Without Cirrhosis [0.03%]
肝硬化患者与非肝硬化患者的感染性休克血管加压药使用时长对比分析
Melissa M Durst,Elizabeth A Eitzen,Scott T Benken
Melissa M Durst
Background: Patients with cirrhosis have immune dysfunction, altered inflammatory response, and hemodynamic changes which increase risk of septic shock and potentially prolong management with fluids, vasopressors, and oth...
Comparison of 3 Different Prothrombin Complex Concentrate Regimens for Emergent Warfarin Reversal: PCCWaR Study [0.03%]
三项紧急逆转华法林不同凝血酶原复合物方案的比较研究：PCCWaR研究
Scott K Dietrich,Shaun Rowe,Craig A Cocchio et al.
Scott K Dietrich et al.
Background: The ideal dose and specific prothrombin complex concentrate (PCC) for warfarin reversal is unknown. Objective: To evaluate ...
Multicenter Study
The Annals of pharmacotherapy. 2021 Aug;55(8):980-987. DOI:10.1177/1060028020978568 2021
Risk of Intracranial Hemorrhage With Concomitant Use of Antidepressants and Nonsteroidal Anti-inflammatory Drugs: A Nested Case-Control Study [0.03%]
抗抑郁药与非甾体抗炎药联合使用导致脑出血的风险：嵌套病例对照研究
Po-Cheng Hou,Fang-Ju Lin,Shin-Yi Lin et al.
Po-Cheng Hou et al.
Background: Whereas previous studies found that concomitant antidepressant and nonsteroidal anti-inflammatory drug (NSAIDs) use may increase the risk of gastrointestinal bleeding, either drug alone increases the risk of i...