A Multicenter, Feasibility Study Exploring Self-Administration of Chemotherapy in the Home Environment: The EASE Study [0.03%]
一项多中心可行性研究：在家庭环境中探索化疗的自我给药：EASE研究
Darius A Ramrattan,Carole Chambers,Peter Duggan et al.
Darius A Ramrattan et al.
Background: Numerous studies have investigated the feasibility of home administration of bortezomib by nurses for the management of multiple myeloma. However, the impact of patient self-administration remains largely unex...
Evaluation of Stress-Dose Steroid Weaning Strategies in Patients Following Septic Shock [0.03%]
重症患者脱离感染性休克压力剂量皮质类固醇的方案评估
Jade M Denninger,John A Toler,Steven Skovran et al.
Jade M Denninger et al.
Background: The 2016 Surviving Sepsis Campaign (SSC) guidelines recommended tapering corticosteroids once vasopressors were no longer needed, while the 2021 update suggested IV hydrocortisone for patients with ongoing vas...
Association of Baseline Comorbidities With First-Year Adherence to GLP-1 Receptor Agonists in Patients With Diabetes or Obesity: A Retrospective Cohort Study [0.03%]
基线合并症与糖尿病或肥胖患者首次使用GLP-1受体激动剂依从性的相关性：一项回顾队列研究
Ziyang Mai,John Kornak,Suzanne M Dufault et al.
Ziyang Mai et al.
Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are increasingly used for diabetes and obesity. Yet, the role of comorbidities on adherence, and variability due to drug subtype or indication remains unde...
Comparison of Continuous Neuromuscular Blocking Agent Titration Strategies in Acute Respiratory Distress Syndrome [0.03%]
不同正压通气策略下肌松药物使用对急性呼吸窘迫综合征患者的疗效和安全性的比较研究
Arilyn Maier,Rachel Kolar,Ahmed Shible et al.
Arilyn Maier et al.
Background: Neuromuscular blocking agents (NMBAs) are suggested as an option in moderate to severe acute respiratory distress syndrome (ARDS) to improve ventilator synchrony (VS) and overall oxygenation. However, NMBA tit...
Comparative Risk of Acute Anemia and Urinary Tract Infection With Sulfamethoxazole-Trimethoprim Versus Dapsone After Kidney Transplant [0.03%]
与达普森相比，肾移植后使用磺胺甲基异噁唑-甲氧苄氨嘧啶导致急性贫血和泌尿系统感染的风险比较研究
Artemis R Huntsman,Christian J Squires,Joy Dray Vongspanich et al.
Artemis R Huntsman et al.
Background: Dapsone is an alternative prophylactic agent for opportunistic infection in kidney transplant recipients (KTRs) with sufficient glucose-6-phosphate dehydrogenase levels. Potential disadvantages include increas...
Chris M Terpening,Jon P Wietholter
Chris M Terpening
Objective: To describe the properties of a newly approved intranasal powder formulation of dihydroergotamine (DHE) for the acute treatment of migraine headaches. ...
Comparison of the Effect of Proton Pump Inhibitors Versus Histamine-2 Receptor Antagonists on Cardiovascular Outcomes on Clopidogrel-Based Dual Antiplatelet Therapy: A Nationwide Cohort Study [0.03%]
一项全国队列研究：比较质子泵抑制剂与组胺H2受体拮抗剂对氯吡格雷基础的双联抗血小板治疗患者的心血管结局影响
Yu Jeong Lee,Nam Kyung Je
Yu Jeong Lee
Background: Dual antiplatelet therapy (DAPT) is essential after percutaneous coronary intervention (PCI) but increases gastrointestinal (GI) bleeding risk, necessitating acid suppressants. The cardiovascular safety of con...
Initial Analgesia and Sedation Requirements in Intensive Care Unit Patients on Prior-to-Admission Buprenorphine/Naloxone [0.03%]
入院前接受布迫芬酮/纳洛酮患者的重症监护室镇痛和镇静需求初探
Erika L Mackie,Amanda Jo Shigle,Sheena L Burwell et al.
Erika L Mackie et al.
Background: To our knowledge, there are no data assessing sedation requirements in patients on buprenorphine/naloxone (Bup/Nx) prior to admission (PTA). O...
Efficacy and Safety of Pitolisant for Excessive Daytime Sleepiness in Narcolepsy and Obstructive Sleep Apnea: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
pitolisant治疗嗜睡型发作性睡眠症及阻塞性睡眠呼吸中止症过日间嗜睡疗效和安全性的最新系统性回顾与元分析：随机临床试验
Amna Amir Jalal,Syed Ibad Hussain,Muhammad Saad Khan et al.
Amna Amir Jalal et al.
Objective: To assess the efficacy and safety of pitolisant, a selective histamine H₃ receptor antagonist/inverse agonist, for excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA). ...
Intrathecal Mixtures, Clinical Practice Versus the Lack of Stability Evidence [0.03%]
鞘内注射药物配制的临床应用与稳定性数据缺乏之间的矛盾
Sandra Caíña López,Carmen Dávila Pousa
Sandra Caíña López