Albumin Versus Crystalloids in Postcardiac Surgery Fluid Resuscitation: A Cost and Safety Analysis [0.03%]
术后心血管手术复苏使用白蛋白与晶体液的费用及安全性分析
Eisa Azhar,Corianne Thackrey,Taylor Menderski et al.
Eisa Azhar et al.
Background: Intravenous fluids are commonly used in postcardiac surgery to maintain or increase intravascular volume. While volume expansion after cardiac surgery is often necessary, the optimal fluid type to use is not e...
The High Cost of Gene Therapy: Managing Onasemnogene Abeparvovec's Economic Impact [0.03%]
基因治疗的高昂成本：管理onasemnogene abeparvovec的经济影响
Eleonora Castellana,Maria Rachele Chiappetta
Eleonora Castellana
FAQs About Pharmacist Management of Uncomplicated Lower Urinary Tract Infections [0.03%]
关于药师管理单纯性下尿路感染的常见问题
Michael Klepser,Ross Tsuyuki,Nathan P Beahm et al.
Michael Klepser et al.
Nontraditional models of care, including pharmacist-led management, have emerged to improve access to evidence-based cystitis treatment. Drawing from studies in Canada, New Zealand, the United Kingdom, and the United States, evidence demons...
Risk Factors Associated With Incident Opioid Prescription Among Attention-Deficit/Hyperactivity Disorder Patients Prescribed Stimulants [0.03%]
注意缺陷多动障碍患者开具刺激剂与新发阿片类药物处方的相关危险因素分析
Mina Shrestha,Chijioke M Okeke,Chan Shen et al.
Mina Shrestha et al.
Background: Pharmacotherapy with stimulant or nonstimulant medications is recommended as first-line treatment for attention-deficit/hyperactivity disorder (ADHD). Among patients prescribed stimulants, concomitant opioid u...
Evaluating the Role of Erythrocyte-Related Markers in Predicting Adenosine Response in Supraventricular Tachycardia [0.03%]
评估红细胞相关标志物在预测房性心动过速腺苷反应中的作用
Seth Carroll,Kathleen Soter,Mallory McGee et al.
Seth Carroll et al.
Background: Supraventricular tachycardia (SVT) accounts for ~50 000 emergency department (ED) visits annually. Adenosine is a commonly used pharmacologic intervention, but predictors of success remain unclear. Erythrocyte...
Safety and Efficacy of the Prescribing Practices of Ketamine for Pain and Agitation in the Medical Intensive Care Unit [0.03%]
重症监护病房中使用氯胺酮止痛和镇静的处方安全性和有效性
Shaelyn Cooper,MaryEllen Antkowiak,Derek Devine et al.
Shaelyn Cooper et al.
Background: Ketamine has analgesic and sedative properties that are thought to reduce opioid tolerance and opioid-induced hyperalgesia. For this reason, ketamine may be used to manage pain and agitation, although the lite...
Comparing Vasopressin and Hydrocortisone as Adjunctive Measures in Septic Shock [0.03%]
血管加压素与氢化可的松作为难治性感染性休克辅助治疗的比较研究
Hannah F Wang,Beena Cheriyan,Marianne Huebner et al.
Hannah F Wang et al.
Background: Norepinephrine has been widely established as the first-line agent for hemodynamic support in septic shock. The timing and order of initiation of vasopressin and hydrocortisone as adjunctive agents remains hig...
Garadacimab-gxii-A Novel Prophylactic Treatment for Hereditary Angioedema: A Drug Review [0.03%]
gardacimab-gxii：遗传性血管性水肿的新型预防治疗药物：药物评价
Kelli M Schindel,Omar Raheel,Chenan A Huang et al.
Kelli M Schindel et al.
Objective: To describe garadacimab-gxii, an antibody that inhibits factor XII, indicated for hereditary angioedema (HAE) prophylaxis, approved by the Food and Drug Administration in June 2025 for patients 12 years and old...
Effect of Sphingosine-1-Phosphate Receptor Modulators on Insulin Resistance: A Review [0.03%]
鞘氨醇-1-磷酸受体调节剂对胰岛素抵抗的影响：综述研究
Sandra Caíña López,Luciano Martínez Martínez,Andrea Bartolomé Figueroa et al.
Sandra Caíña López et al.
Objective: The objective is to review the potential impact of sphingosine-1-phosphate (S1P) receptor modulators on insulin resistance in patients with multiple sclerosis, including underlying mechanisms and clinical evide...
Transdermal "Natural GLP-1" Dietary Supplements Violate Law and Place Patients at Risk [0.03%]
违规的经皮“天然GLP-1”膳食补充剂令患者处于危险之中
C Michael White,Zeeya Tai,Klaus Nuzi
C Michael White
Consumers precluded from obtaining semaglutide or tirzepatide by clinicians or insurers are turning to natural "GLP-1" transdermal patches. The Dietary Supplement Health and Education Act specifies dietary supplement products must be swallo...