Compounded Semaglutide and Tirzepatide Products Use Unique Formulations but Efficacy and Safety Largely Unknown [0.03%]
复方司美格鲁肽和 tirzepatide 产品采用独特的配方，但其疗效和安全性尚不清楚
Jordyn Belcourt,Amy Sapowadia,C Michael White
Jordyn Belcourt
Background: With the shortage of innovator semaglutide or tirzepatide products resolved, compounding pharmacies can only legally sell unique products. Unique products could have a different route of administration or dosi...
The Efficacy and Safety of Ketamine or Ketorolac Compared to Opioids in Painful Vaso-Occlusive Crisis: A Response and Subgroup Analysis [0.03%]
关于ketamine或ketorolac与阿片类药物在血栓闭塞性危机止痛方面有效性和安全性的系统综述和 meta 分析：回复及亚组分析
May M Shehata,Justin P Reinert
May M Shehata
Comment on "The Efficacy and Safety of Ketamine or Ketorolac Compared to Opioids in Painful Vaso-Occlusive Crisis: A Systematic Review and Meta-Analysis" [0.03%]
关于“酮酚洛塞与阿片类药物对比治疗血栓闭塞性危象疼痛的疗效和安全性：系统评价和 meta 分析”的评述
Ramenani Hari Babu,Singh Shekhar Gautam,Sulakshana Pal Singh et al.
Ramenani Hari Babu et al.
Lauren M Hynicka,Jessica Battaglia
Lauren M Hynicka
Tofersen: A Novel Option for the Treatment of Amyotrophic Lateral Sclerosis [0.03%]
托芬司 Pegnemer（Tofersen）：治疗肌萎缩侧索硬化的新选择
Michael Karros,Marissa DiFulco,Anna Nogid
Michael Karros
Objective: This review summarizes current evidence on the efficacy and safety of tofersen (Qalsody) in treating amyotrophic lateral sclerosis (ALS). Data ...
Biologic Treatments in Adolescents With Moderate-to-Severe Atopic Dermatitis: A Systematic Literature Review and Network Meta-analysis [0.03%]
中至重度特应性皮炎青少年患者生物制剂治疗的系统文献回顾和网状meta分析
Kevin H Li,Emily K Duffy,Jonathan Luong et al.
Kevin H Li et al.
Background: Novel interventions, particularly biologic therapies, have been shown to be efficacious and safe in treating atopic dermatitis (AD) in adolescents. However, the comparative efficacy and safety of biologic inte...
Effect of Propranolol on Hyperthermia Secondary to Paroxysmal Sympathetic Hyperactivity in Critically Ill Patients With Traumatic Brain Injury [0.03%]
普萘洛尔对创伤性脑损伤危重患者突发性交感神经亢进继发的高热的影响
Kameron Walker,Joseph M Swanson,Saskya Byerly et al.
Kameron Walker et al.
Background: Patients with traumatic brain injury (TBI) may develop paroxysmal sympathetic hyperactivity (PSH), a syndrome manifesting as cyclic increases in vital signs and motor activity. Previous studies show propranolo...
Comparison of Train-of-Four Versus No Train-of-Four Monitoring of Neuromuscular Blockade on Drug Consumption for Acute Respiratory Distress Syndrome [0.03%]
比较神经肌肉阻滞监测中使用和不使用四车效应对于急性呼吸窘迫综合征患者的药物消耗情况
Kayleigh N Yaeger,Ryan M Rivosecchi,Julie N Clarkson et al.
Kayleigh N Yaeger et al.
Background: There is limited data regarding the use of clinical assessment alone for neuromuscular blockade (NMB) titrations in the setting of acute respiratory distress syndrome (ARDS). ...
Effect of Conversion From Intravenous to Oral Administration on Cyclosporine Exposure in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation [0.03%]
从静脉转换为口服给药对儿科同种异体造血干细胞移植环孢素暴露的影响
Junyan Wang,Meng Zhang,Lingkun Wang et al.
Junyan Wang et al.
Background: Cyclosporine is an immunosuppressant extensively used for the prevention and treatment of graft-vs-host disease (GvHD) in pediatric allogeneic hematopoietic stem cell transplantation (allo-HSCT). Converting th...