A Comparison of Monotherapy and Combination Therapy With Antipsychotic Medications for Intensive Care Unit Delirium: A Retrospective Cohort Study [0.03%]
抗精神病药物单药治疗与联合治疗重症监护室谵妄的比较：一项回顾性队列研究
Anh Nguyen,Justin Chang,Timothy Allison-Aipa et al.
Anh Nguyen et al.
Background: Antipsychotic medications continue to be frequently prescribed by clinicians in the intensive care unit (ICU) for delirium, despite inconclusive data. ...
Dupilumab Use in Eosinophilic Esophagitis: Analysis of the FDA Adverse Event Reporting System Database [0.03%]
dupilumab治疗嗜酸细胞性食管炎的用药分析：基于FDA不良事件数据库的研究
Michael B Andrews,Hiba Khan,Douglas G Adler
Michael B Andrews
Sodium Zirconium Cyclosilicate for the Acute Management of Hyperkalemia in the Emergency Department [0.03%]
急诊科应用硫酸锌环硅酸锆钠治疗高钾血症
Nicole Gasparovic,Amanda Buckallew,Sara Richter
Nicole Gasparovic
Background: Limited evidence exists examining the use of potassium binders for the acute management of hyperkalemia. Objective: The obj...
Management of Direct Oral Anticoagulants Surrounding Placement or Revision of Cardiac Implantable Electronic Devices [0.03%]
直接口服抗凝药在心脏植入式电子设备置入或更换过程中的管理
Anna Crider,Clara Ting,Julie Kelly Doyle et al.
Anna Crider et al.
Background: Pocket hematoma is a rare complication in patients on anticoagulation after placement of cardiac implantable electronic devices (CIEDs). Current guidance for periprocedural management of direct oral anticoagul...
Evaluating Rebound Hypotension Following Vasopressor Discontinuation Strategies in Patients With Septic Shock [0.03%]
评估感染性休克患者血管加压药停用策略后的反跳性低血压
Skyler Starkel,Brian R Schuler,Mary P Kovacevic et al.
Skyler Starkel et al.
Background: The 2021 Surviving Sepsis guidelines recommend which vasopressor to initiate first; however, there is a paucity of data to guide the order of vasopressor discontinuation. Retrospective studies have demonstrate...
Overview of Challenges With Using Cost-Effectiveness Analysis for Evaluating Medications [0.03%]
成本效益分析在药品评估中应用的挑战综述
Christopher J Edwards,Brian L Erstad
Christopher J Edwards
Countries such as Australia with universal healthcare perform cost-effectiveness evaluations of new prescription medications. In the United States, there is no assessment of cost-effectiveness analysis at the national level with the notable...
Nicholas W Carris,Shawn Wallace,Marilyn Stern et al.
Nicholas W Carris et al.
Clinical Outcomes of Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 RA) and Glucagon-Like Peptide-1/Glucose-Dependent Insulinotropic Polypeptide Receptor Agonist (GLP-1/GIP RA) Exposures Presenting to the Emergency Department [0.03%]
急诊科就诊的胰高血糖素样肽-1受体激动剂（GLP-1RA）和胰高血糖素样肽-1/葡萄糖依赖性促胰岛素多肽受体激动剂（GLP-1/GIP RA）暴露的临床结局
Hayley T Gartner,Reeves E Simmons,Herbert Z Wan et al.
Hayley T Gartner et al.
Background: Glucagon-like peptide-1 receptor agonist (GLP-1 RA) and glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptor agonist (GLP-1/GIP RA) use has become increasingly popular, leading to a ri...
Impact of Remdesivir on Heart Rate and Bradycardia Incidence Among Hospitalized Adults With COVID-19 [0.03%]
瑞德西韦对住院成人COVID-19患者心率和心动过缓的影响
Wesley D Kufel,Zoey J Zagoria,Robert W Seabury et al.
Wesley D Kufel et al.
Background: Bradycardia is not currently described as an adverse effect in prescribing information for remdesivir but has been reported postapproval. Therefore, effects on heart rate (HR) and bradycardia incidence after r...
Bradley Phillips,Cierra Abbott,Savanna Breit et al.
Bradley Phillips et al.
Objective: This review aims to evaluate the efficacy and safety of olezarsen (Tryngolza) in treating familial chylomicronemia syndrome (FCS), a rare genetic disorder characterized by severe hypertriglyceridemia. ...