Comparative Efficacy and Safety of Basal/Correctional Vs Basal/Bolus/Correctional Insulin Regimens in Medical Intensive Care Unit Patients Receiving Continuous Enteral Nutrition [0.03%]
连续肠内营养的医疗重症监护病房患者的基础/校正与基础/餐时/校正胰岛素方案的疗效和安全性比较研究
Jessica Briscoe,Lauren Caldwell,Aaron Cohen et al.
Jessica Briscoe et al.
Background: While glycemic control is essential in critically ill patients, the optimal insulin regimen for patients receiving continuous enteral nutrition (CEN) is unknown. ...
Real-World Safety Profile of Ibrutinib in Chronic Lymphocytic Leukemia: A Focus on Adverse Events, Discontinuations, and Effectiveness Outcomes [0.03%]
伊布替尼治疗慢性淋巴细胞白血病的现实世界安全性：关注不良事件、停药及疗效结果
Alejandro Martínez Pradeda,Pablo Feijoo Vilanova,Elena Fernández Gabriel et al.
Alejandro Martínez Pradeda et al.
Background: Ibrutinib has transformed chronic lymphocytic leukemia (CLL) treatment, offering significant survival benefits in clinical trials. However, real-world evidence is essential to understand its safety and efficac...
Mental Health Caught in the Crossfire: Selective Serotonin Reuptake Inhibitors (SSRIs), Stigma, and the Political Debate [0.03%]
受夹击的精神健康：选择性5-羟色胺再摄取抑制剂、污名化与政治争论
Cameron Lanier,Tyler Melton
Cameron Lanier
Recent rhetoric in the media and from the United States Federal Government has called into question the effectiveness of antidepressants, namely selective serotonin reuptake inhibitors (SSRIs), among other psychiatric pharmacotherapies. Sel...
Systematic Literature Review of DOACs as Treatment for Confirmed or Suspected Heparin-Induced Thrombocytopenia (HIT) [0.03%]
关于DOAK治疗确诊或疑似肝素诱导的血小板减少症(HIT)的系统文献回顾
Shoshana Steinmetz,Anastasiya Shor,Michelle Jakubovics
Shoshana Steinmetz
Objective: To analyze available literature on the use of direct oral anticoagulants (DOACs) in the treatment of confirmed or suspected heparin-induced thrombocytopenia (HIT). ...
Evaluation of an Alternative Approach to Managing Diabetic Ketoacidosis: Combination Rapid-Acting and Basal Subcutaneous Insulin (CRABI-DKA) [0.03%]
评估糖尿病酮症酸中毒管理的替代方法：速效和基础胰岛素联合皮下注射(CRABI-DKA)方案的效果评价
Francisco Ibarra Jr,Mallory Cruz,Brian Chinnock et al.
Francisco Ibarra Jr et al.
Background: Although guidelines recognize the utility of subcutaneous (SQ) insulin regimens in the management of mild to moderate diabetic ketoacidosis (DKA), the need to administer SQ insulin every 1-2 hours may discoura...
Comment on "Association Between Rocuronium Administration and Clinical Outcomes in Patients With Moderate-To-Severe Acute Respiratory Distress Syndrome: A Retrospective Cohort Study" [0.03%]
急性中重度呼吸窘迫综合征患者使用rozconium的临床结果：回顾性队列研究的点评
Venkata Dileep Kumar Veldi,Ranjana Sah
Venkata Dileep Kumar Veldi
Effects of Cholinesterase Inhibitor Medication on QTc Interval in Memory Clinic Patients [0.03%]
胆碱酯酶抑制剂对记忆门诊患者QTc间期的影响
Hanna Karita Isotalo,Joanna Karoliina Lehtovaara,Laura Linnea Ekblad et al.
Hanna Karita Isotalo et al.
Background: Cholinesterase inhibitors (ChEIs)-donepezil, rivastigmine, and galantamine-are beneficial in treating Alzheimer disease (AD). However, due to their impact on extra-cerebral acetylcholine signaling, concerns ab...
Partial Courses of Fidaxomicin Followed by Oral Vancomycin and the Effect on Recurrence of Clostridioides difficile Infections [0.03%]
fidaxomycin短期治疗继以口服万古霉素对预防艰难梭菌感染复发的影响
Irene-Constantina Papamanolis,Nicholas Stornelli,Nathan Everson et al.
Irene-Constantina Papamanolis et al.
Background: Clostridioides difficile infection (CDI) causes a significant national health care burden. Literature has demonstrated lower rates of CDI recurrence with fidaxomicin compared with oral vancomycin. However, pat...
Evaluating the Concomitant Use of Diltiazem or Verapamil With Direct Oral Anticoagulants: A Meta-analysis [0.03%]
地尔硫卓或维拉帕米与直接口服抗凝剂联合使用的效果：一项荟萃分析
Kazuhiko Kido,Mikiko Shimizu,Tsuyoshi Shiga et al.
Kazuhiko Kido et al.
Background: Diltiazem and verapamil are combined p-glycoprotein and moderate CYP3A4 inhibitors which significantly increase the concentrations of direct oral anticoagulants (DOACs) and may increase the risks of bleeding. ...
Gabapentinoïds and Hip Fracture: A Pharmacovigilance Comparative Study Between Gabapentin and Pregabalin [0.03%]
加巴喷丁类与髋部骨折：加巴喷丁和普瑞巴林的药物警戒比较研究
Jean-Louis Montastruc
Jean-Louis Montastruc