Therapeutic Drug Monitoring of Voriconazole: Unbound Concentration With Clinical Efficacy and Adverse Events [0.03%]
伏立康唑治疗药物监测：血药游离浓度与临床疗效和不良事件的关系研究
Tiantian Zhang,Zhicong Qiu,Wenhao Chu et al.
Tiantian Zhang et al.
Background: Voriconazole is widely used for patients with fungal infections, but the correlations between the unbound concentration (Cfree) of voriconazole in plasma and clinical outcomes remains unclear. ...
Early Clinical Response is Associated With a Decreased Risk of Recurrent Pseudomonas aeruginosa Ventilator-Associated Pneumonia [0.03%]
早期临床反应与肺炎克雷伯氏菌所致呼吸机相关性肺炎复发风险降低有关
Alex S Huang,Jing J Zhao,Ryan Gumbleton et al.
Alex S Huang et al.
Background: Current data suggest that short-course therapy for Pseudomonas aeruginosa ventilator-associated pneumonia (PA-VAP) may increase the risk of recurrent pneumonia. To decrease antibiotic exposure without adversel...
What's Your C. diff-erential? Evaluating Clinical Management of Discordant Clostridioides difficile Two-Step Testing [0.03%]
您是否正确解读了艰难梭菌两步法检测的不符结果？
Adam Siddique,Nicolas Daoura,Punit J Shah
Adam Siddique
Jimmy Dhillon,Aryan Mahajan,Joy Xie et al.
Jimmy Dhillon et al.
Objective: This article reviews clinical trial data that assess the safety, efficacy, and clinical application of roflumilast, a phosphodiesterase-4 inhibitor, for the treatment of seborrheic dermatitis. ...
Hydrocortisone Dosing Frequency in Intensive Care Unit Patients With Septic Shock: A Comparison of 2 Regimens [0.03%]
不同剂量强化肾上腺皮质功能对重症监护病房中脓毒症休克患者的影响：对比两种方案
Abigail Danos,Alyssa Lear,Erin Roach et al.
Abigail Danos et al.
Background: In patients with septic shock, intravenous (IV) hydrocortisone is recommended when there is an ongoing vasopressor requirement. Guidelines recommend IV hydrocortisone 200 mg/day administered as a continuous in...
Comment: Safety of Phenobarbital Versus Benzodiazepines for Alcohol Withdrawal in Critically Ill Patients with Primary Neurologic Injuries [0.03%]
评论：苯巴比妥与苯二氮卓类药物在重症酒精依赖合并原发神经损伤患者中的安全性比较
Travis Hanson,Frank Paloucek,Abigail Elmes-Patel
Travis Hanson
Reply: Impact of Remdesivir on Heart Rate and Bradycardia Incidence Among Hospitalized Adults With COVID-19 [0.03%]
利巴韦林对COVID-19住院成人患者心率和心动过缓的影响答复：瑞德西リン对COVID-19住院成人患者心率和心动过缓的影响
Wesley D Kufel,Robert W Seabury,Sarah A Spinler
Wesley D Kufel
Comment: Impact of Remdesivir on Heart Rate and Bradycardia Incidence Among Hospitalized Adults With COVID-19 [0.03%]
来那度韦对成人COVID-19住院患者心率及心动过缓影响的点评
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
The Rates of Bleeding and Venous Thromboembolism with Reduced-Dose Enoxaparin for Thromboprophylaxis in Low-Weight Surgical Patients: A Retrospective Cohort Study [0.03%]
低体重手术患者使用减量依诺肝素进行血栓预防的出血和静脉血栓栓塞事件发生率：回顾性队列研究
Hakeam Hakeam,Amjaad Alfahed,Hanin Aldalham et al.
Hakeam Hakeam et al.
Background: Low body weight is a recognized risk factor for bleeding with standard enoxaparin thromboprophylaxis (40 mg daily). Although reduced enoxaparin doses are used for venous thromboembolism (VTE) prevention in low...
Impact of Glucagon-like Peptide-1 Receptor Agonists on Bowel Preparation for Colonoscopy: A Large, Matched Regional Cohort [0.03%]
glucagon样肽-1受体激动剂对结肠镜检查肠道准备影响的区域队列研究
Jennifer L Cole,Jennifer E Stark
Jennifer L Cole
Background: Poor colon preparation may negatively affect colonoscopy accuracy, result in cancelation, or need for repeat procedure. The glucagon-like peptide-1 receptor agonist (GLP-1RA) class of medications delay gastric...