National Stockpiling of Pediatric Cancer Medications in the United States: An Alternative Approach to Hospital-Based Storage for Essential Oncology Drugs [0.03%]
美国国家层面上的儿童肿瘤药物储备：一种替代性的基于医院的必需肿瘤药物储存方法
Maxwell L Izen,Mia Lynch,Charles L Bennett
Maxwell L Izen
Despite continued efforts, pediatric oncology patients face, at times, insurmountable barriers to cancer medication access, creating an ongoing public health crisis with potentially tragic consequences. These shortages adversely impact pedi...
Lyndsey Reich,Kevin B Knopf
Lyndsey Reich
The ongoing shortage of oncology drugs, particularly generic chemotherapies like platinum agents, has had a disproportionate impact on community and safety net hospitals in the United States and globally. These institutions, often serving r...
The Oncology Drug Shortage: ASCO's Vision and Proposals for Resolving This Public Health Emergency [0.03%]
肿瘤药物短缺：ASCO关于解决这一公共健康紧急事件的愿景与建议
Jason Westin,Dominic Sawaya,Shimere Williams Sherwood et al.
Jason Westin et al.
The issue of drug shortages is a persistent and complex one. There is an urgent need for a wide-ranging, multifaceted strategy to address drug shortages and bold, comprehensive solutions. Professional societies, such as the American Society...
Oncology Drug Shortages: Impacts, Policy Reforms, and Advocacy Imperatives [0.03%]
肿瘤药物短缺：影响、政策改革与倡导要求
Marissa Malta,Matthew Christian,Amy B Cadwallader
Marissa Malta
Oncology drug shortages have reached unprecedented levels and have had a substantial impact on the treatment of cancer patients, which can include medication rationing, delayed treatments, and inferior therapeutic substitutions. This manusc...
Key Drivers and Mitigation Strategies of Oncology Drug Shortages 2023 to 2025 [0.03%]
2023-2025年肿瘤药物短缺的主要驱动因素及缓解策略
Mariana P Socal,Joy Acha,Chia-Yu Yang et al.
Mariana P Socal et al.
Drug shortages remain a problem in the United States, jeopardizing patient care. To help inform solutions, this study reviewed recent oncology drug shortages for causes and mitigation strategies. Using the FDA's Drug Shortage Database, 15 o...
Maxwell L Izen,June M McKoy,Linda Martin et al.
Maxwell L Izen et al.
The Trump Administration has signaled its intent to impose tariffs on pharmaceuticals worldwide, raising uncertainty about the potential impact on cancer treatments in the United States. Increasing concern surrounds the possibility that the...
Mitigating the Impact of Drug Shortages in Oncology: Lessons Learned From the 2023 Shortages of Carboplatin and Cisplatin [0.03%]
应对肿瘤学药物短缺的影响：2023年卡铂和顺铂短缺的教训
Maxwell L Izen,June M McKoy,Linda Martin et al.
Maxwell L Izen et al.
Purpose/background: Cancer drug shortages adversely affect cancer patient care and ultimately cancer patient lives. Shortages of cancer drugs used for pediatric cancer patients are well described. ...
Introduction to a Supplement From the Cancer Journal: The Journal of Principles and Practice of Oncology [0.03%]
肿瘤杂志： oncology：原则与实践增刊序言
Charles L Bennett,Kevin B Knopf
Charles L Bennett
Alternative Radiotherapy Delivery Approaches to Modulate Radiation Response [0.03%]
用于调节放射反应的替代放疗递送方法
Joanna Wilk,Carol Box,Kevin Harrington et al.
Joanna Wilk et al.
Spatially fractionated (SFRT) and FLASH radiotherapy (RT) are alternative means of dose delivery that are expected to widen the therapeutic window of clinical RT. The biological mechanisms for the observed effects of normal tissue-sparing w...
Jacky K Leung,Ryan Panchal,Selvakumar Anbalagan et al.
Jacky K Leung et al.
Redox biology plays an important role in cancer progression and therapy resistance. Tumor cells maintain elevated levels of reactive oxygen species to support proliferation while upregulating antioxidant defences to avoid oxidative cell dea...