Future Directions and Emerging Approaches in the Treatment of Brain Metastases [0.03%]
脑转移治疗的未来方向和新兴方法
Rifaquat Rahman,Minesh Mehta
Rifaquat Rahman
The management of brain metastases is increasingly complex and requires multidisciplinary input from a wide array of experts, including radiation oncology, medical oncology, neurosurgery, and palliative care. Novel radiation techniques, rad...
Nicole Hajdari,David M Peereboom
Nicole Hajdari
Brain metastases are a common yet dismal complication of metastatic cancers, originating most commonly from nonsmall cell lung cancer, breast cancer, melanoma, and renal cell carcinoma. While the current standard of care for most patients i...
Adannia Ufondu,Jana Haroun,Samuel Chao et al.
Adannia Ufondu et al.
Radiation necrosis (RN) is a serious complication of stereotactic radiosurgery (SRS), affecting ∼5% to 25% of patients treated for brain metastases. Because RN is a late effect of radiation therapy with a typical onset of 6 to 12 months af...
The Role of Artificial Intelligence for the Radiotherapeutic Management of Brain Metastases [0.03%]
人工智能在脑转移瘤放射治疗管理中的作用
Alexander Podgorsak,John Kang,Dandan Zheng et al.
Alexander Podgorsak et al.
As the radiotherapeutic management of brain metastases increasingly utilizes stereotactic radiosurgery (SRS) and repeated treatments, artificial intelligence (AI) applications are being investigated in treatment planning, prognostication, a...
Brittney Chau,Eric Lin Chang,Adam Garsa
Brittney Chau
Brain metastases affect up to 30% of cancer patients and can cause significant neurological effects. Treatment of brain metastases requires a multidisciplinary approach with surgery, radiation modalities, and systemic therapy all playing a ...
Advanced Imaging Techniques for the Detection and Follow-up of Brain Metastases [0.03%]
高级影像技术在脑转移瘤检测和随访中的应用
Hang Yu,Hany Soliman,Kang Liang Zeng et al.
Hang Yu et al.
Optimal management of patients with brain metastases relies on both accurate detection on initial imaging and accurate differentiation between treatment-related effects from progression on follow-up imaging. Contrast-enhanced MRI remains th...
Praveen Pendyala,Adannia Ufondu,Vinai Gondi
Praveen Pendyala
Whole brain radiation therapy (WBRT) continues to play a critical role in managing patients with extensive brain metastases, but neurocognitive decline remains a significant limitation. This review examines the clinical presentation and und...
Alexander Becker,Alejandro Carrasquilla,Michael A Vogelbaum
Alexander Becker
Surgical resection is an important treatment consideration for patients with brain metastases, as it offers rapid symptom relief and enhances local control. Although surgery remains a mainstay of treatment, there exists increasing nuance in...
Biology of Brain Metastases [0.03%]
脑转移的生物学特性
Ozum Atasoy,Eyub Y Akdemir,Rupesh Kotecha
Ozum Atasoy
Brain metastases affect up to 40% of patients with cancer and represent a major clinical challenge. Despite advances in surgery, radiotherapy, and systemic therapies, outcomes remain modest, partly due to the blood-brain barrier and the lim...