Commentary: bevacizumab and erlotinib with chemoradiation for head and neck cancer [0.03%]
贝伐单抗和厄洛替尼联合放化疗治疗头颈部肿瘤的评论文章
Barbara Burtness
Barbara Burtness
Combined modality treatment with chemotherapy, radiation therapy, bevacizumab, and erlotinib in patients with locally advanced squamous carcinoma of the head and neck: a phase II trial of the Sarah Cannon oncology research consortium [0.03%]
头颈部鳞状细胞癌综合化疗、放疗、贝伐单抗和厄洛替尼二期临床试验：Sarah Cannon肿瘤研究联盟报告
John D Hainsworth,David R Spigel,F Anthony Greco et al.
John D Hainsworth et al.
Purpose: : The aim of the study was to evaluate the feasibility and efficacy of adding bevacizumab and erlotinib to concurrent chemoradiation therapy for first-line treatment of patients with locally advanced squamous car...
Sublobar versus lobar resection for stage I non-small cell lung cancer: Alice's evidence [0.03%]
孤立性肺结节亚肺叶切除 vs. 肺叶切除：何去何从？
Hisato Takagi,Masafumi Matsui,Takuya Umemoto
Hisato Takagi
Patrick M Blake,David A Decker,Timothy M Glennon et al.
Patrick M Blake et al.
Around the world, teams of researchers continue to develop a wide range of systems to capture, store, and analyze data including treatment, patient outcomes, tumor registries, next-generation sequencing, single-nucleotide polymorphism, copy...
State-level cancer quality assessment and research: building and sustaining the data infrastructure [0.03%]
基于州的癌症质量评估和研究：建立和维持数据基础设施
Joseph Lipscomb,Theresa W Gillespie
Joseph Lipscomb
Over a decade ago, the Institute of Medicine called for a national cancer data system in the United States to support quality-of-care assessment and improvement, including research on effective interventions. Although considerable progress ...
Informatics in clinical research in oncology: current state, challenges, and a future perspective [0.03%]
临床肿瘤研究中的生物信息学：现状、挑战与未来展望
Amar P S Chahal
Amar P S Chahal
The informatics landscape of clinical trials in oncology has changed significantly in the last 10 years. The current state of the infrastructure for clinical trial management, execution, and data management is reviewed. The systems, their f...
Informatics in action: lessons learned in comparative effectiveness research [0.03%]
informatics在行动：有效性研究中的经验教训
Bradford R Hirsch,Robert B Giffin,Laura C Esmail et al.
Bradford R Hirsch et al.
Comparative effectiveness research (CER) is meant to provide evidence about the relative risks and benefits of different treatment options. It is gaining visibility as a tool to address the evidence gaps that clinicians struggle with every ...
Ethan M Basch,Bryce B Reeve,Sandra A Mitchell et al.
Ethan M Basch et al.
Understanding the potential profile of adverse events associated with cancer treatment is essential in balancing safety versus benefits. Multiple stakeholders make use of this information for decision making, including patients, clinicians,...
Bradford W Hesse,Jerry M Suls
Bradford W Hesse
For the practicing physician, the behavioral implications of preventing, diagnosing, and treating cancer are many and varied. Fortunately, an enhanced capacity in informatics may help create a redesigned ecosystem in which applying evidence...
Paul K Courtney
Paul K Courtney
In 2001, the Institute of Medicine report Crossing the Quality Chasm and the National Committee on Vital and Health Statistics report Information for Health were released, and they provided the context for the development of information sys...