Determinants of Septic Shock and 90-Day Mortality after Postoperative Healthcare-Associated Intra-Abdominal Infection: The SEPSI-POP study, a Multicentre Retrospective Study [0.03%]
术后医院相关性腹内感染后发生脓毒性休克及90天死亡率的影响因素：多中心回顾性研究（SEPSI-POP研究）
Djamel Mokart,Antoine Bianchi,Romain Ronflé et al.
Djamel Mokart et al.
Background: Healthcare-associated intra-abdominal infections (HC-IAIs) after abdominal surgery are a major cause of sepsis in intensive care units (ICUs). While predictors of mortality are well established, the determinan...
A Meta-Analytic Perspective on Echocardiographic Signs of Long-Term Cardiac Dysfunction After Burns, Sepsis, and Trauma [0.03%]
烧伤、脓毒症和创伤后长期心脏功能障碍的超声心动图征象的元分析观点
Tobias Niederegger,Emre Karakas,Thomas Schaschinger et al.
Tobias Niederegger et al.
Severe burns, major trauma, and sepsis cause systemic inflammation and metabolic stress, often leading to acute cardiac dysfunction. How myocardial sequelae evolve over time remains unclear. This meta-analysis evaluated whether consistent e...
Venous-to-Arterial Carbon Dioxide Gradient and Its Ratio to Arterial-central Venous Oxygen Content Difference in Assessing Oxygen Metabolism and Tissue Perfusion in Septic Shock: A Prospective Observational Study [0.03%]
静脉-动脉二氧化碳分压梯度及其与动-中心静脉氧含量差比值在评估感染性休克患者氧代谢和组织灌注中的作用：一项前瞻性观察研究
Sizhuo Kou,Kun Jiang,Jijia Bai et al.
Sizhuo Kou et al.
Background: Traditional biomarkers such as lactate and central venous oxygen saturation (ScvO₂) have limitations in accurately reflecting tissue perfusion and oxygen metabolism in septic shock. This study investigates th...
Assessment Of Novel Platform Of Thrombin Generation To Predict Venous Thromboembolism Early After Traumatic Injury: A Prospective Cohort Study [0.03%]
评估新型凝血酶生成平台预测创伤后早期静脉血栓栓塞的效果：前瞻性队列研究
Sergio M Navarro,Riley J Thompson,Taleen A MacArthur et al.
Sergio M Navarro et al.
Introduction: Calibrated automated thrombography (CAT) assay parameters have been shown to assess hypercoagulation state and, therefore, may independently predict post-trauma, symptomatic venous thromboembolism (VTE). Yet...
Association Between Different Glucocorticoids and Mortality in ICU Patients With Sepsis-related Acute Respiratory Distress Syndrome: A Retrospective cohort study from MIMIC-IV Database [0.03%]
不同糖皮质激素与脓毒症相关急性呼吸窘迫综合征重症监护病房患者死亡率的关系：来自MIMIC-IV数据库的回顾性队列研究
Jiayang Huang,Zhikun Xu,Jiajia Huang et al.
Jiayang Huang et al.
Background: The comparative effectiveness of specific glucocorticoids (methylprednisolone, hydrocortisone, and dexamethasone) and the impact of dosing intensity on outcomes in sepsis-associated acute respiratory distress ...
A Systematic Review Of Machine Learning Models For Sepsis Prediction: An Appraise-Ai Approach [0.03%]
利用Appraise-AI方法对败血症预测的机器学习模型进行系统性回顾
Tingrui Wang,Qinqin Li,Zhangyi Wang et al.
Tingrui Wang et al.
Background: Sepsis, a leading cause of ICU mortality and high healthcare costs, results from a systemic inflammatory response to infection. Early detection is crucial but challenging. Machine learning models present a pro...
Characterization of a Rabbit Model of Traumatic Hemorrhagic Shock under High-Altitude Cold Conditions [0.03%]
高寒条件下兔创伤失血性休克模型的建立及特征分析
Weihao Chai,Han Shi,Jiajia Li et al.
Weihao Chai et al.
High-altitude hypoxia and cold often co-occur in traumatic hemorrhagic shock (THS), yet time-resolved models that quantify their interaction with blood loss are scarce. We established a composite-trauma THS model in New Zealand rabbits at ...
Development and validation of Machine Learning model to predict refractory septic shock [0.03%]
机器学习模型预测难治性脓毒性休克的发展与验证
Vinay Gandhi Mukkelli,Puneet Khanna,Amit Mehndiratta et al.
Vinay Gandhi Mukkelli et al.
This study developed and validated a Machine Learning (ML) model to predict refractory septic shock (RSS) in patients with sepsis admitted to a tertiary care center in India. Using an ambispective design, data from 1,008 adult ICU patients ...
Early Immune Phenotype-Guided Immunomodulatory Strategies and Intensive Care Outcomes in Septic Shock: A Single-Center Retrospective Cohort Study [0.03%]
免疫表型指导的免疫调节策略在休克中的早期应用及其对预后影响：一项回顾性队列研究
Mustafa Said Aydogan,Vahap Saricicek
Mustafa Said Aydogan
Background: Septic shock is characterized by profound immune dysregulation, with marked heterogeneity in host inflammatory and immunosuppressive responses. This biological variability may contribute to the inconsistent ef...
Regulation of IRGM1-Mediated Pyroptosis and Neuroinflammation by Transcription Factor NR3C1 Alleviates Early Brain Injury After Subarachnoid Hemorrhage [0.03%]
转录因子NR3C1通过调节IRGM1介导的焦亡和神经炎症缓解动脉瘤性蛛网膜下腔出血后的早期脑损伤
Yuanjun Xin,Min Gong,Xiaohong Fu
Yuanjun Xin
Background: Early brain injury (EBI) following subarachnoid hemorrhage (SAH) is critical for patient prognosis, and neuroinflammation and pyroptosis play core roles in its pathological process. Immunity-related GTPase 1 (...