Assessment of Sublingual Microcirculation to Evaluate the Efficacy of Resuscitation Therapy in Septic Shock Patients: A cohort study [0.03%]
评估舌下微循环作为评价脓毒性休克患者复苏治疗效果的指标：队列研究
Xiaolei Zhang,Haisong Zhang,Rui Jin et al.
Xiaolei Zhang et al.
Objectives: Determining the endpoint of resuscitation in septic shock is essential to enhance effectiveness, prevent over-resuscitation, and improve outcomes. We designed this study to investigate whether sublingual micro...
Re-increases in C-reactive protein in patients with sepsis are associated with the development of persistent inflammation, immunosuppression, and catabolism syndrome [0.03%]
败血症患者的C-反应蛋白再次升高与持续性炎症、免疫抑制和分解代谢综合征相关
Takuma Kishimoto,Naoto Mizumura,Jun Matsubayashi et al.
Takuma Kishimoto et al.
Background: Multiple insults, such as infection and trauma, can induce the features of persistent inflammation, immunosuppression, and catabolism syndrome (PICS) in animal models. ...
A Retrospective Cohort Study on 28-Day Mortality in Immunosuppressed Sepsis: An Interpretability-Based Predictive Model Using MIMIC-IV v2.2 [0.03%]
一项关于免疫抑制患者的脓毒症28天死亡率的回顾性队列研究：使用MIMIC-IV v2.2进行可解释性的预测模型研究
Zhiru Zhong,Huiwei He,Zhiying Lin
Zhiru Zhong
Background: Sepsis in immunosuppressed patients is associated with significantly higher mortality rates, yet predictive models tailored to this high-risk population remain limited. This study aims to develop an interpreta...
Abnormal Platelet-to-Lymphocyte Ratio is Associated with Poor Outcomes in Pediatric Sepsis [0.03%]
血小板淋巴细胞比率异常与儿童脓毒症不良预后的相关性研究
Carine S Abi Gerges,Courtney M Rowan,Francis Pike et al.
Carine S Abi Gerges et al.
Objective: Sepsis remains a major cause of morbidity and mortality in children, necessitating an early risk assessment to prevent delayed treatment and achieve optimal outcomes. This study investigated the association bet...
Mortality in the Sepsis-3 Era: A Systematic Review of Multicenter Randomized Controlled Trials [0.03%]
Sepsis-3时代多中心随机对照试验的死亡率系统评价
Marko Nemet,I Serhat Karakus,G Cameron Gmehlin et al.
Marko Nemet et al.
This systematic review examined multicenter randomized controlled trials (RCTs) conducted during the Sepsis-3 era that evaluated pharmaceutical and mechanistic interventions in adult patients with sepsis or septic shock, with a focus on ide...
Association Between Geriatric Nutritional Risk Index and the Progression of Chronic Critical Illness and Short-term Prognosis in Sepsis Patients [0.03%]
营养风险指数与脓毒症患者慢性重症进展和短期预后之间的联系研究
Chaowei Wang,Zhiyuan Zhang,Jiangui Wang et al.
Chaowei Wang et al.
Background: The impact of nutritional status on the advancement to chronic critical illness (CCI) in sepsis patients is not well understood. This study aimed to explore the connection between the nutritional risk index (G...
Impaired fatty liver regeneration post-major resection: a mitochondrial problem [0.03%]
大肝切除术后脂肪性肝再生障碍：线粒体问题所致？
Tyler P Robinson,Tewfik Hamidi,Yanlin Jiang et al.
Tyler P Robinson et al.
Fatty liver disease is associated with a markedly increased risk of liver dysfunction and death after major hepatectomy. We previously demonstrated impaired hepatocyte proliferation, delayed liver regeneration, and increased mortality in po...
Epidemiology and Risk Factors of Sepsis and Sepsis-Induced Myocardial Dysfunction in the Intensive Care Units of Tertiary Hospitals [0.03%]
我国三级医院重症监护病房脓毒症及其心肌损害的流行病学与危险因素分析
Gui-Jun Zhu,Yan Huo,Yu-Chun Yin et al.
Gui-Jun Zhu et al.
Sepsis and sepsis-induced myocardial dysfunction (SIMD) are critical conditions associated with high mortality in intensive care units (ICUs). This study aimed to characterize the clinical profiles of sepsis and SIMD in tertiary ICUs, ident...
Endothelial Activation and Stress Index Elevation Associated with Adverse Prognosis in Sepsis-associated acute kidney injury Patients: Validation Based on Two Critical Care Cohorts [0.03%]
内皮激活和应激指数升高与脓毒症相关急性肾损伤患者的不良预后有关：两项重症监护队列研究的验证结果
Zhiyuan Zhang,Chaowei Wang,Jiangui Wang et al.
Zhiyuan Zhang et al.
Background: Sepsis-associated acute kidney injury (SA-AKI) is a prevalent complication in critical care settings with high mortality. Early identification of high-risk patients is crucial. The Endothelial Activation Stres...
Artificial oxygen carriers: lessons from hemoglobin-based oxygen carrier clinical trials and current development efforts [0.03%]
人工氧载体：基于血红蛋白携带氧气的临床试验及当前开发工作的经验和现状
Youmna Abdelghany,Matthew B Amdahl,Qinzi Xu et al.
Youmna Abdelghany et al.
The clinical benefit of blood transfusion is undeniable, and yet reliance on donated blood products has several shortcomings. These include risks of supply shortages due to reliance on volunteer donors, short storage life, and potential inf...