Gut Microbiota Modulation Attenuates Myocardial Ischemia-Reperfusion Injury in Diabetic Mice [0.03%]
调节糖尿病小鼠肠道菌群减轻心肌缺血再灌注损伤
Kanako Takahashi,Yusuke Yoshikawa,Tomohiro Chaki et al.
Kanako Takahashi et al.
Background: The gut microbiome is increasingly being recognized as a regulator of cardiometabolic health; however, whether microbiome interventions can attenuate myocardial ischemia-reperfusion injury (IRI) in diabetic he...
Phoenixin-14 attenuates oxidative multi-organ damage in sepsis-induced rats [0.03%]
凤凰宁对脓毒症大鼠氧化性多器官损伤的保护作用研究
Zarife Nigâr Özdemir Kumral,Leyla Semiha Şen,Çiğdem Çantali-Öztürk et al.
Zarife Nigâr Özdemir Kumral et al.
Sepsis is a critical clinical condition characterized by life-threatening multi-organ dysfunction resulting from a dysregulated host response to infection. This study evaluated the individual and combined anti-inflammatory effects of Phoeni...
Meta-analysis of the prognostic value of skin perfusion parameters in sepsis patients: Evidence integration based on the Mottling Score, capillary refill time, and peripheral perfusion index [0.03%]
严重感染患者皮肤灌注参数预后价值的meta分析：MOTTLED评分、甲皱微循环毛细血管充盈时间和外周灌注指数证据整合
Li Juan Shi,Shu Fen Ke,Li Mei Zhu et al.
Li Juan Shi et al.
Background: Despite advances in intensive care, sepsis and septic shock still have high morbidity and mortality. Microcirculatory disturbance is a key issue in sepsis, leading to hypoperfusion, hypoxia, and organ failure....
Development and External Validation of a Propensity Score-Matched Predictive Model for 48-Hour Intensive Care Unit Readmission in Patients With Sepsis [0.03%]
脓毒症患者48小时重症监护室再入院倾向评分匹配预测模型的开发和外部验证
Tenghao Shao,Qi Yang,Xiaozhen Nie et al.
Tenghao Shao et al.
Objective: This study aimed to develop and validate a clinically applicable predictive model for estimating the probability of intensive care unit (ICU) readmission within 48 hours following ICU discharge in patients with...
Temporal Aquaporin Expression Profiles in Immune Cell Subsets during Critical Illness [0.03%]
危重症期间免疫细胞亚群的水通道蛋白动态表达特征
Nikolaos S Lotsios,Vasileios Issaris,Georgios Poupouzas et al.
Nikolaos S Lotsios et al.
Aquaporins (AQPs) are a family of water channel proteins with a significant role in immune cell function. Although aquaporins have been studied in sepsis, their expression in critical illness remains underexplored. Our group aimed to examin...
Tocilizumab Therapy in Gram-Positive and Gram-Negative Pediatric Septic Shock: A Comparative Pilot Study [0.03%]
托珠单抗治疗儿童阳性菌和阴性菌感染所致休克的比较试点研究
Kiew-Kii Lau,Jainn-Jim Lin,Oi-Wa Chan et al.
Kiew-Kii Lau et al.
Background: Elevated interleukin-6 (IL-6) is strongly associated with disease severity and mortality in pediatric septic shock. This study investigated whether adjunctive tocilizumab, a humanized anti-IL-6 receptor antibo...
Identifying a Refractory Shock Phenotype in Pediatric Sepsis Using a Vasoactive-Adjusted Shock Index [0.03%]
基于血管活性调整的休克指数识别儿童难治性感染性休克表型
Cheolmin Matthew Lee,Mihir R Atreya,Tellen D Bennett et al.
Cheolmin Matthew Lee et al.
Objectives: This study aimed to (1) develop a cardiovascular index that includes hemodynamic status and adjusts for vasoactive medication use, (2) identify pediatric patients with refractory septic shock (RSS) using early...
Reply - Letters to the Editor by Hübner, Berlot, Bottari et al.: Clinical and Immunologic Effects of Extracorporeal Cytokine Removal in Patients with Septic Shock: A Randomized Controlled Trial [0.03%]
赫布纳、贝尔洛特、博塔里等人来信的回复：脓毒性休克患者体外细胞因子清除的临床和免疫学效应：一项随机对照试验
Christopher Lotz,Johannes Heckelmann,Clara Lendzian et al.
Christopher Lotz et al.
Comment to: Lotz et al. "Clinical and Immunologic Effects of Extracorporeal Cytokine Removal in Patients With Septic Shock: A Randomized Controlled Trial" [0.03%]
对Lotz等“脓毒性休克患者体外细胞因子清除的临床和免疫学效应：随机对照试验”的评论
Berlot Giorgio,Axel Nierhaus,Dominik Jarczak
Berlot Giorgio
Blood Glucose Trajectories and Mortality in Sepsis-Induced Coagulopathy: A Latent Growth Mixture Modeling Analysis [0.03%]
latent growth mixture modeling分析败血症凝血病血糖轨迹与死亡率的关系
Kai Qi,Chenjia Guo,Linhua Yang
Kai Qi
Background: Sepsis-induced coagulopathy (SIC) is a severe complication contributing significantly to mortality in critically ill patients. While hyperglycemia is a known risk factor, the prognostic value of longitudinal b...