Shock-Induced Endothelial Dysfunction is Present in Patients With Occult Hypoperfusion After Trauma [0.03%]
隐匿性低灌注创伤患者的内皮功能障碍
Heather R Kregel,Gabrielle E Hatton,Kayla D Isbell et al.
Heather R Kregel et al.
Background: Shock-induced endothelial dysfunction, evidenced by elevated soluble thrombomodulin (sTM) and syndecan-1 (Syn-1), is associated with poor outcomes after trauma. The association of endothelial dysfunction and o...
Observational Study
Shock (Augusta, Ga.). 2022 Jan 1;57(1):106-112. DOI:10.1097/SHK.0000000000001866 2022
A New Time-Window Prediction Model For Traumatic Hemorrhagic Shock Based on Interpretable Machine Learning [0.03%]
基于可解释机器学习的创伤性出血性休克新的时间窗预测模型
Yuzhuo Zhao,Lijing Jia,Ruiqi Jia et al.
Yuzhuo Zhao et al.
Early warning prediction of traumatic hemorrhagic shock (THS) can greatly reduce patient mortality and morbidity. We aimed to develop and validate models with different stepped feature sets to predict THS in advance. From the PLA General Ho...
Inhibition of the Interaction of TREM-1 and eCIRP Attenuates Inflammation and Improves Survival in Hepatic Ischemia/Reperfusion [0.03%]
抑制TREM-1和eCIRP的相互作用可减轻肝缺血再灌注中的炎症并提高生存率
Timothy Borjas,Asha Jacob,HaoTing Yen et al.
Timothy Borjas et al.
Introduction: Triggering receptor expressed on myeloid cells-1 (TREM-1) has important implications in sepsis and inflammation and is a novel receptor for extracellular cold-inducible RNA-binding protein (eCIRP). We hypoth...
Cardiogenic Shock Complicating ST-Segment Elevation Myocardial Infarction: An 18-Year Analysis of Temporal Trends, Epidemiology, Management, and Outcomes [0.03%]
ST段抬高型心肌梗死并发的心源性休克：18年来的趋势、流行病学、管理及结果分析
Saraschandra Vallabhajosyula,Nakeya Dewaswala,Pranathi R Sundaragiri et al.
Saraschandra Vallabhajosyula et al.
Background: There are limited data on the temporal trends, incidence, and outcomes of ST-segment-elevation myocardial infarction-cardiogenic shock (STEMI-CS). ...
Renal Resistive Index on Intensive Care Unit Admission Correlates With Tissue Hypoperfusion Indices and Predicts Clinical Outcome [0.03%]
入重症监护室时肾阻力指数与组织低灌注指标相关并可预测临床结局
Georgia Fotopoulou,Ioannis Poularas,Stelios Kokkoris et al.
Georgia Fotopoulou et al.
Background: Renal resistive index (RRI) has been used to evaluate renal blood flow. Our aim was to investigate the relation between RRI and global tissue hypoperfusion indices and their association with clinical outcome, ...
Autoresuscitation of Poloxamer 188 in Pigs With Traumatic Severe Hemorrhage [0.03%]
聚氧乙烯(188)能使创伤大出血的猪自动复生
Wenjun Z Martini,Hui Xia,Irasema Terrazas et al.
Wenjun Z Martini et al.
Background: Poloxamer 188 (P188) is a copolymer surfactant with plasma membrane stabilizing action. This study investigated the effects of P188 on blood volume and coagulation in pigs after traumatic hemorrhage and hypote...
Prognostic Values of Platelet Distribution Width and Platelet Distribution Width-to-Platelet Ratio in Severe Burns [0.03%]
血小板分布宽度及血小板分布宽度与血小板比值在严重烧伤中预后价值的研究
Jian-Chang Lin,Guo-Hua Wu,Jian-Jun Zheng et al.
Jian-Chang Lin et al.
Background: Platelet distribution width (PDW) and PDW-to-platelet ratio (PPR) have been proven to be good prognostic indicators for many diseases. However, their prognostic values in severe burns have not been reported. ...
Relationships Between Age, Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1), and Mortality Among Critically Ill Adults: A Cohort Study [0.03%]
年龄，可溶性髓样细胞触发受体-1(sTREM-1)和危重成人死亡率之间的关系：一项队列研究
Neha A Sathe,Pavan K Bhatraju,Carmen Mikacenic et al.
Neha A Sathe et al.
Background: Innate immune dysregulation may contribute to age-related differences in outcomes among critically ill adults. Soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) is an important innate immune m...
Lipopolysaccharide-Induced Cytokine Secretion from In Vitro Mouse Slow and Fast Limb Muscle [0.03%]
脂多糖诱导的体外小鼠慢快腿肌细胞因子分泌反应
Alex J Mattingly,Orlando Laitano,Christian K Garcia et al.
Alex J Mattingly et al.
Skeletal muscles play important roles in innate immunity. However, in vitro, their sensitivity to LPS is low. In other tissues, LPS sensing is facilitated by the presence of plasma, LPS binding protein (LBP), or soluble CD14 (sCD14). This s...
Predictors of Mortality in Neonatal Shock: A Retrospective Cohort Study [0.03%]
新生儿休克死亡的预测因素：一项回顾性队列研究
Shiv Sajan Saini,Amit Kumar Shrivastav,Jogender Kumar et al.
Shiv Sajan Saini et al.
Objectives: To study the incidence, clinical profile, and predictors of mortality in neonatal shock. Methods: We enrolled consecutive i...