In patients with AF and obesity, catheter ablation vs. lifestyle modification plus antiarrhythmic drugs improved AF freedom at 1 y [0.03%]
与服用抗心律失常药物的生活方式改良相比，导管消融可改善肥胖房颤患者1年的无房颤率
Mohammed Ruzieh;ACP Journal Club Editorial Team at McMaster University
Mohammed Ruzieh;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
In cancer-associated thrombosis, DOACs reduce VTE and increase clinically relevant nonmajor bleeding vs. LMWH at 3 to 12 mo [0.03%]
在癌症相关血栓形成中 较LMWH而言 直接口服抗凝药减少VTE并增加临床相关的非大出血(随访3至12个月)
Alejandro Godoy,James D Douketis;ACP Journal Club Editorial Team at McMaster University
Alejandro Godoy
GIM/FP/GP: [Formula: see text] Oncology: [Formula: see text] Hematology: [Formula: see text].
In older adults at risk for dementia, a structured vs. self-guided lifestyle intervention improved cognitive function over 2 y [0.03%]
结构化生活方式干预比自我导向的生活方式干预更好改善有患痴呆症风险的老年人的认知功能
Terry Quinn;ACP Journal Club Editorial Team at McMaster University
Terry Quinn;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text] Geriatrics: [Formula: see text] Public Health: [Formula: see text].
Effectiveness of Psychological Therapies for Depression During the Perinatal Period : A Systematic Review and Meta-analysis [0.03%]
围产期抑郁心理治疗效果的系统评价和 meta 分析
Elyse Couch,Htun Ja Mai,Ghid Kanaan et al.
Elyse Couch et al.
Background: Perinatal depression can have a deleterious impact on mothers and infants. Purpose: To evaluate psychological therapies for...
Overdue: Delayed Revision of Institutional Review Board Policies Characterizing Pregnant Women After the Revised Common Rule [0.03%]
亟待解决的问题：《修订后的通用规则》施行后机构审查委员会有关孕产妇政策迟迟未改
Caleigh Propes,Stephanie R Morain
Caleigh Propes
After endocrine therapy for postmenopausal early breast cancer, allocation to aromatase inhibitors reduced recurrence at 10 y [0.03%]
绝经后期乳腺癌内分泌治疗之后他莫昔芬换用芳香化酶抑制剂可降低十年间的复发风险
Nicholas Wilcken;ACP Journal Club Editorial Team at McMaster University
Nicholas Wilcken;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text].
In minor stroke, adding IV thrombolysis to nonthrombolytic usual care does not increase excellent functional outcome at 90 d [0.03%]
在小卒中患者中，在非溶栓常规治疗基础上加用静脉组织型纤溶酶原激活剂(thrombolysis with alteplase)注射并未提高90天时的良好功能预后率
Avi Singh Gandh,Mithilesh Siddu,Dinesh Jillella;ACP Journal Club Editorial Team at McMaster University
Avi Singh Gandh
Emergency Med: [Formula: see text] GIM/FP/GP: [Formula: see text] Neurology: [Formula: see text].
In adults with obesity but without type 2 diabetes, tirzepatide increased weight loss at 72 wk compared with semaglutide [0.03%]
在没有2型糖尿病的肥胖成人中， Tirzepatide的体重损失效果优于Semaglutide，持续长达72周
Lenard I Lesser;ACP Journal Club Editorial Team at McMaster University
Lenard I Lesser;ACP Journal Club Editorial Team at McMaster University
GIM/FP/GP: [Formula: see text] Endocrinology: [Formula: see text].