SOX2 Can Support a Diagnosis of PiMHEC With Rare to Absent Ghost Cells and Can Distinguish PiMHEC From Its Most Problematic Mimickers [0.03%]
SOX2有助于诊断罕见的或缺乏影细胞的PiMHEC，并可将PiMHEC与其最难鉴别的类似病变相区分
Jin Xu,Paul S Weisman
Jin Xu
Pilomatrix-like high-grade endometrioid carcinoma (PiMHEC) is an aggressive variant of endometrioid adenocarcinoma characterized by divergent pilomatrical differentiation. While classic cases are usually recognizable, the diagnosis can be c...
PAX8-Negative HPV-Associated Endocervical Adenocarcinoma With a Micropapillary Component: A Diagnostic Pitfall Mimicking Metastatic Carcinoma [0.03%]
PAX8阴性HPV相关宫颈部腺癌伴微乳头状成分：易误诊为转移性肿瘤的一类诊断陷阱
Furkan Aknar,Sevil Albayrak,Dorukhan Gül et al.
Furkan Aknar et al.
An Endometrioid Carcinoma With an Adenoma Malignum-like Pattern of Invasion: New Insight into Molecular Features [0.03%]
具有恶性腺瘤样浸润模式的内膜样癌的新分子特征
Meng Jia,Shi-Li Yu,Ping-Li Sun
Meng Jia
Adenoma malignum-like (AM-L) pattern is the least common invasion type in endometrioid carcinoma of the uterus and is characterized by a bland morphologic appearance in accordance with International Federation of Gynecology and Obstetrics G...
Endometrial Mesonephric-like Carcinosarcoma With Shared KRAS, TP53, and RB1 Mutations: Report of a Rare Case Highlighting Diagnostic Challenges and Novel Molecular Insights, and Review of the Literature [0.03%]
具有共享KRAS、TP53和RB1突变的子宫内膜中肾样癌肉瘤罕见病例报告：强调诊断挑战和新型分子见解，并进行文献回顾
Zitong Zhao,Timothy Kwang Yong Tay,Tony Kiat Hon Lim et al.
Zitong Zhao et al.
Mesonephric-like carcinosarcoma (MLCS) is an uncommon gynecologic malignancy comprising mesonephric-like adenocarcinomatous (MLA) and high-grade (HG) sarcomatous elements. We describe an endometrial MLCS in a 63-yr-old woman showing diverge...
Tumor Grade in Molecularly Defined Endometrial Carcinoma: Prognostic Implications of the ESGO-ESTRO-ESP 2025 Guidelines [0.03%]
分子定义的子宫内膜癌的肿瘤分级：ESGO-ESTRO-ESP 2025指南的预后意义
Mikko Loukovaara,Annukka Pasanen,Ralf Bützow
Mikko Loukovaara
As an update to the 2021 guidelines, the 2025 endometrial carcinoma risk classification by the European Society of Gynaecological Oncology (ESGO), the European Society for Radiotherapy and Oncology (ESTRO), and the European Society of Patho...
Comparative Molecular Profiling of Basal Cell Carcinomas in Sun-Exposed and Anogenital Regions [0.03%]
紫外线暴露区域和肛生殖区域基底细胞癌的分子特征比较分析
Ahlam Ali,Pelin Onur,Anas Mohamed et al.
Ahlam Ali et al.
Basal cell carcinoma (BCC) is the most common skin malignancy and is strongly associated with ultraviolet (UV) radiation. However, BCC arising in sun-protected areas such as the anogenital region remains poorly characterized. To compare the...
Bilateral Ovarian Anastomosing Hemangioma Mimicking Malignancy: A Frozen Section Diagnostic Pitfall [0.03%]
双侧卵巢吻合血管瘤似恶性肿瘤：术中冷冻切片诊断难题
Camilla Gennaioli,Nataniele Piol,Anjeza Xholli et al.
Camilla Gennaioli et al.
Anastomosing hemangioma is a benign vascular neoplasm originally described in the genitourinary tract, but subsequently reported in a variety of anatomic sites. Although ovarian involvement has been documented, bilateral localization has no...
Genetic Stability of Short Tandem Repeat (STR) Loci in Human Term Placentas [0.03%]
人胎盘短期重复序列（STR）遗传稳定性研究
Na Niu,Natalia Buza,Pei Hui
Na Niu
Short tandem repeat (STR) genotyping is widely used in human identity testing and is the gold standard for diagnosing and classifying hydatidiform moles and gestational trophoblastic neoplasms. Although STR loci are known to be highly stabl...
HPV-independent Squamous Cell Carcinoma With Choriocarcinomatous Differentiation in Uterine Cervix: Case Report With Molecular Characterization [0.03%]
一种带有绒毛膜癌分化的HPV阴性宫颈鳞状细胞癌病例报道及其分子特征分析
Lei Ye,Bingjian Lu
Lei Ye
This report pertains to a rare case of cervical squamous cell carcinoma (SCC) with choriocarcinomatous (CC) differentiation in a 77-yr-old woman. The patient developed lung and mediastinal metastases 3 mo after surgery and died at 5 mo. His...
p53 Overexpression in an Ovarian Adult Granulosa Cell Tumor Without Anaplastic Morphology: A Marker of Aggressive Behavior? [0.03%]
p53过度表达在无肉瘤形态的卵巢成人颗粒细胞肿瘤中：恶性的标志？
Reiji Muto,Nao Yamamoto,Mika Takaki et al.
Reiji Muto et al.
Adult granulosa cell tumor (AGCT) is a pure-type sex cord tumor of the ovary that shows a low-grade morphology. Despite being classified as malignant, it typically demonstrates indolent clinical behavior. Histologic grading is not tradition...