High-grade Invasive Papillary Urothelial Carcinoma Arising in a Mature Cystic Teratoma of the Ovary: A Case Report, Including Its Molecular Profile, and a Literature Review [0.03%]
卵巢成熟性囊性畸胎瘤中发生的高级别乳头状尿路上皮癌一例报告（包括分子分型及其文献复习）
Patricia A Repollet Otero,Preetha Ramalingam,Michael W Bevers et al.
Patricia A Repollet Otero et al.
Urothelial carcinoma arising in a mature cystic teratoma of the ovary is a rare event with only 13 cases reported thus far. In this article, we present the clinicopathologic features of one such case and a review of the literature. The pati...
Nodular Fasciitis of the Vulva: Clinicopathologic Features and Diagnostic Pitfalls With Molecular Confirmation [0.03%]
会阴纤维性肌炎的临床病理特征及分子确认诊断陷阱
Ahmet Erbağci,İlker Nihat Ökten,Gözde Kir
Ahmet Erbağci
Nodular fasciitis (NF) is a benign, self-limited myofibroblastic proliferation that typically arises in the subcutaneous tissues of the extremities and trunk, while vulvar involvement is distinctly rare. Owing to its rapid growth and histol...
High-grade Endometrial Stromal Sarcoma With a Novel ING3::BCOR Fusion [0.03%]
一种新型ING3::BCOR融合的高级别子宫内膜间质肉瘤
Istem Kose,Saloni Walia
Istem Kose
High-grade endometrial stromal sarcoma (HGESS) is a rare tumor that typically occurs over a wide age range, from 14 to 71 yr, often presenting with nonspecific clinical symptoms. This tumor group displays heterogeneous tumor morphology and ...
PRAME Expression in HPV-associated and Differentiated Vulvar Intraepithelial Neoplasia-associated Vulvar Squamous Neoplasia [0.03%]
与HPV相关的和分化型外阴Bowen病及其他外阴鳞状细胞瘤中PRAME的表达差异
Eyas Alzayadneh,Sarah E Gradecki,Landon K Hobbs et al.
Eyas Alzayadneh et al.
Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry was initially used diagnostically in melanoma but is increasingly evaluated across malignancies for diagnostic, prognostic, and therapeutic purposes. PRAME protein ac...
Clinicopathologic and Prognostic Significance of Tumor Budding in Endometrial Cancer: A Systematic Review and Meta-Analysis [0.03%]
子宫内膜癌中肿瘤芽生的临床病理和预后意义系统评价和meta分析
Mishu Mangla,Seetu Palo,Bhoomika Katravath et al.
Mishu Mangla et al.
Although tumor budding has emerged as an indicator of tumor aggressiveness in several solid cancers, its prognostic significance in endometrial cancer is not well studied. This systematic review and meta-analysis aimed to quantify the assoc...
Clinicopathologic and Immunologic Features of Vulvar Lichen Sclerosus and Related Neoplasia: A Comparative Study of Precursor Lesions and VSCC in Premenopausal and Postmenopausal Patients [0.03%]
外阴硬化性苔藓及相关的肿瘤的临床病理和免疫表型研究：绝经前和绝经后患者癌前病变与VSCC比较研究
Elayna Shanker,Alberto Moscona,Luis Chiriboga et al.
Elayna Shanker et al.
Lichen sclerosus (LS) is a chronic inflammatory condition of the vulva. Although LS is thought to arise from autoimmune mechanisms, it is unclear whether disease drivers differ by menopausal status-an important distinction given its potenti...
Proteomic Validation of MUC4 in the Differential Diagnosis of Endometrial and Ovarian Serous Carcinomas [0.03%]
蛋白质组学验证MUC4在子宫内膜癌和卵巢浆液性癌鉴别诊断中的作用
Hale Kivrak,Ezgi Dicle Serbes,Egemen Akincioglu et al.
Hale Kivrak et al.
Endometrial serous carcinoma (ESC) and high-grade ovarian serous carcinoma (HG-OSC) share morphologic, immunohistochemical, and molecular features, and the determination of the primary tumor site is challenging, particularly in cases with b...
Müllerian Adenosarcoma of the Cervix: A Rare Case Highlighting Site-Specific Diagnostic and Management Challenges [0.03%]
宫颈müllerian腺肉瘤：一个罕见病例，强调部位特异性诊断和管理挑战
Rachel Camarena,Esther Adler
Rachel Camarena
Mullerian adenosarcomas are biphasic tumors with benign epithelium and malignant stroma, typically found in the uterine corpus but rarely in the cervix, ovaries and other locations. A diagnostic pitfall is misdiagnosis as benign polyps due ...
p53 Normal and p53 Abnormal Clear Cell Ovarian Carcinomas: Clinical Characteristics and Biomarker Profiles [0.03%]
p53正常和p53异常的卵巢透明细胞癌：临床特征及生物标志物谱型分析
Piret Hellberg,Annukka Pasanen,Jonna Similä-Maarala et al.
Piret Hellberg et al.
A new concept of molecular classification for clear cell ovarian carcinoma (CCOC) has been proposed: TP53 wild-type and TP53 mutated. Our aim was to evaluate this classification at the immunohistochemical level in p53 normal and abnormal su...
Uterine Myxoid Inflammatory Myofibroblastic Sarcoma (MIMS) Harboring Pathogenic KRAS Mutations and Expressing ER, PR, and CD10 [0.03%]
具有致癌KRAS突变并表达ER、PR和CD10的子宫粘液样炎性肌纤维母细胞瘤(MIMS)
Jin Xu,David Kushner,Paul S Weisman
Jin Xu
Myxoid inflammatory myofibroblastic sarcoma (MIMS) is a recently described aggressive sarcoma with deceptively bland spindled cells with a myofibroblastic phenotype and myxoid stroma. These tumors are negative for ALK gene rearrangements, b...