Triple Hormone Receptor Agonism: The Role of Retatrutide in Addressing Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Comprehensive Review [0.03%]
Ashwin A Pillai,Shea-Lee Godin,William H Frishman et al.
Ashwin A Pillai et al.
Retatrutide is a first-in-class, unimolecular triple hormone receptor agonist targeting glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1, and glucagon receptors. By synergizing incretin-mediated central satiety with glu...
Karim Bitar,Jad Abdul Khalek,Rana Zareef et al.
Karim Bitar et al.
Sodium-glucose cotransporter 2 inhibitors have demonstrated substantial cardiovascular and renal benefits in adults, including reduced heart failure events across diabetic and nondiabetic populations. However, pediatric cardiac data remain ...
Muhammad Abdullah,Noman Khalid,William H Frishman et al.
Muhammad Abdullah et al.
Cardiovascular disease and chronic kidney disease remain the leading causes of morbidity and mortality in patients with type 2 diabetes, even when conventional risk factors are well managed. Two drug classes have emerged over the past decad...
From Lumen to Myocardium With Artificial Intelligence: A Clinician's Guide to Comprehensive Cardiac CT [0.03%]
Abbas Mohammadi,Seyedhesamoddin Khatami,Sheida Ebrahimi et al.
Abbas Mohammadi et al.
Coronary artery disease assessment has long focused on stenosis severity, yet luminal narrowing alone fails to capture ischemic burden, plaque vulnerability, or myocardial health. This mismatch drives unnecessary invasive coronary angiograp...
PCSK9 as a Biomarker and Therapeutic Target for Anthracycline Cardiotoxicity Prevention: Recent Advancements and Future Perspectives [0.03%]
Ahmed Farid Gadelmawla,Mohanad A Alkuwaiti,Amal A Alsubaiei et al.
Ahmed Farid Gadelmawla et al.
Anthracycline-induced cardiotoxicity continues to be a significant clinical challenge in oncology, affecting up to 30% of patients who are subjected to sequential chemotherapy regimens and substantially restricting the therapeutic potential...
Jie Tan,Jiahan Ke,Xiaohan Qiu et al.
Jie Tan et al.
With advancing age and the development of risk factors such as hypertension, type 2 diabetes, obesity, and atrial fibrillation, the incidence of heart failure with preserved ejection fraction (HFpEF) has shown a year-on-year increase and is...
Cyanotic Congenital Heart Disease in Pregnancy: A Comprehensive Review of Pathophysiology, Maternal-Fetal Outcomes, and Contemporary Management [0.03%]
Kristjana Frangaj,Kateryna Strubchevska,Olena Strubchevska et al.
Kristjana Frangaj et al.
Advances in pediatric cardiac surgery and medical management have enabled an increasing number of women with cyanotic congenital heart disease to reach reproductive age and contemplate pregnancy. Maternal complications occur in approximatel...
Treatment and Outcomes for Acute Ischemic Stroke in Cardiomyopathy Patients With Heart Failure: A Retrospective Cross-Sectional Study [0.03%]
心力衰竭的卡迪迈基opathy患者的急性缺血性卒中的治疗及预后：一项回顾性横断面研究
Aarti Kishore Jain,Nimrod Gozum,Serena Wong et al.
Aarti Kishore Jain et al.
Cardiomyopathy (CM) is a common cause of heart failure (HF), and those with HF have up to a 3-fold increased risk of stroke. This study aims to examine the incidence of intravascular thrombolysis and endovascular thrombectomy and the functi...
Contemporary Management of Ascending Aortic and Arch Dissection: Integrating Open, Hybrid, and Endovascular Strategies [0.03%]
主动脉根部置换术的长期结果：401例马方综合征患者的回顾性分析
Antônio Agostinho Moura Filho,Adnaldo da Silveira Maia,Luciana Rascov et al.
Antônio Agostinho Moura Filho et al.
Acute aortic dissection is the most frequent presentation of acute aortic syndromes and remains a rapidly progressive and life-threatening condition requiring immediate diagnosis and treatment. Advances in surgical techniques, hybrid strate...
Long-Term Oxygen Therapy and Cardiovascular Physiology: Divergent Effects in Heart Failure and Pulmonary Hypertension [0.03%]
长期氧疗与心血管生理：在心力衰竭和肺动脉高压中的不同效应
Josef Kusayev,Shrikant Nayak,William H Frishman et al.
Josef Kusayev et al.
Long-term oxygen therapy (LTOT) is a cornerstone of management for chronic hypoxemic respiratory diseases, such as chronic obstructive pulmonary disease, yet its physiological impact as a potent modulator of cardiovascular function remains ...