The Senescent Heart's Hidden Drain: Senescence-Associated Secretory Phenotype-Mediated Cardiac Lymphatic Dysfunction as a Novel Mechanistic Axis in Heart Failure With Preserved Ejection Fraction: A Narrative Review [0.03%]
衰老心脏的隐性漏损：细胞衰老相关分泌表型介导的心力衰竭伴射血分数保留患者淋巴回流障碍：综述文章
Ahmed Wael Moftah
Ahmed Wael Moftah
Heart failure with preserved ejection fraction (HFpEF) represents the dominant and most therapeutically recalcitrant phenotype of heart failure in the contemporary era, yet its pathophysiology remains incompletely delineated. This narrative...
Type 2 Myocardial Infarction in Patients With Cardiorenal Vulnerability: Mechanisms, Diagnostic Challenges, and a Proposed Clinical Pathway [0.03%]
心血管肾脏脆弱性患者二型心肌梗死的机制、诊断挑战及临床路径建议
Muneera O AlTaweel,Ibrahim Ahmed Alquhays,Khalid Abdullatif Alhuwayji
Muneera O AlTaweel
Type 2 myocardial infarction is defined by myocardial necrosis from supply-demand mismatch in the absence of acute atherothrombosis. It remains a heterogeneous entity without dedicated clinical guidelines or a validated management pathway. ...
Left Atrial Myopathy as a Phenotypic Axis in HFpEF: Implications for Pulmonary Hypertension, Exercise Intolerance, and Targeted Therapy [0.03%]
特发性左心房肌病与射血分数保留型心力衰竭的表型轴：对肺动脉高压、运动不耐受及靶向治疗的意义
Mahwish Jabeen,Saeeda Younas,Ayesha Majid et al.
Mahwish Jabeen et al.
Heart failure with preserved ejection fraction (HFpEF) is a highly heterogeneous syndrome characterized by impaired ventricular relaxation, systemic inflammation, and multisystem cardiovascular dysfunction. Despite growing recognition of HF...
Antra Patel,Tzvi Fishkin,Amgad N Makaryus et al.
Antra Patel et al.
Cardiovascular disease remains the leading cause of morbidity and mortality among women globally, with growing evidence suggesting that cardiovascular risk can begin developing well before pregnancy, even during the preconception period. Am...
Left Atrial Myopathy Across the Spectrum of Pediatric Heart Disease: Imaging, Mechanobiology, and Clinical Consequences [0.03%]
儿科心脏病谱系中左心房肌病的影像学、力学生物学和临床后果
Raima Muqaddas,Sania Nawaz,Sarah Ali et al.
Raima Muqaddas et al.
Left atrial (LA) function has emerged as a critical determinant of cardiovascular performance and disease progression across the spectrum of pediatric heart disease. Traditionally viewed as a passive conduit, the left atrium is now increasi...
Interplay Between Valvular Heart Disease and Psychiatric Disorders: Mechanisms, Manifestations, and Management [0.03%]
心脏瓣膜病与精神疾病之间的相互作用：机制、表现和管理
Alexander Suchodolski,Szymon Florek,Aleksandra Mikunda-Gaweł et al.
Alexander Suchodolski et al.
Valvular heart disease (VHD) and psychiatric disorders are each highly prevalent, yet their co-occurrence is underappreciated in clinical practice. Patients carrying both diagnoses present particular management challenges because the pathol...
Cardiac Auscultation: A Practical Review of Technique, Modern Tools, and Strategies to Maintain Diagnostic Competence [0.03%]
听诊复习：技术、现代工具及维持诊断能力策略概述
Santiago Acero-Velasquez,Juanita Guzman-Correa,Diego A Vivas-Giraldo
Santiago Acero-Velasquez
Cardiac auscultation remains a fundamental component of the cardiovascular physical examination and an essential skill for diagnosing valvular heart disease. Despite its clinical importance, persistent deficiencies in auscultatory proficien...
Ventricular Tachycardia Ablation in Nonischemic Cardiomyopathy: Is Pulsed Field Ablation the Next Paradigm Shift? [0.03%]
非缺血性心肌病室速的消融治疗：脉冲电场消融是下一个变革吗？
Omnia Kamel,Eslam Ahmed,Khalid Sawalha et al.
Omnia Kamel et al.
Ventricular tachycardia ablation in nonischemic cardiomyopathy remains limited by high recurrence rates despite advances in catheter-based techniques. In nonischemic cardiomyopathy, the arrhythmogenic substrate is often heterogeneous and ma...
Pulsed Field Versus Cryoballoon Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis [0.03%]
心房颤动的脉冲场消融与冷冻球囊消融的系统评价和 meta 分析
Muhammad Burhan,Momina Siddiqui,Maliha Khalid et al.
Muhammad Burhan et al.
In the treatment of atrial fibrillation (AF), cryoballoon ablation (CBA) is associated with a high incidence of pulmonary vein reconnection, potentially limiting long-term efficacy. Pulsed field ablation (PFA) has emerged as a promising alt...
SGLT2 Inhibitors in the Modern Cardiology Era: Mechanisms, Outcomes, and Clinical Applications [0.03%]
现代心脏病学中的SGLT2抑制剂：机制、结果和临床应用
Negarsadat Neshat,Padideh Daneii,Sina Neshat et al.
Negarsadat Neshat et al.
Sodium-glucose cotransporter-2 (SGLT2) inhibitors were initially developed as antihyperglycemic agents for type 2 diabetes mellitus but have become foundational therapies in cardiovascular and cardiorenal medicine. Randomized trials and met...