Exercise and insulin: Convergence or divergence at AS160 and TBC1D1? [0.03%]
运动与胰岛素：在AS160和TBC1D1上的汇聚或分歧？
Gregory D Cartee,Katsuhiko Funai
Gregory D Cartee
Akt substrate of 160 kDa (called AS160 or TBC1D4) and TBC1D1, Rab GTPase-activating proteins that regulate glucose transport, become phosphorylated with exercise or insulin stimulation. Evidence suggests that this convergence may prove to b...
Cross-education of strength depends on limb dominance: implications for theory and application [0.03%]
交叉教育效应的强度依赖于 limbs dominance：理论与实践意义
Jonathan P Farthing
Jonathan P Farthing
Cross-education of strength is much greater when the dominant arm is trained in right-handed individuals. This asymmetry of strength transfer in the upper limbs is similar to what has been shown for skill transfer between limbs. The discuss...
Activity-dependent plasticity of spinal locomotion: implications for sensory processing [0.03%]
脊髓行走活动的可塑性及其对感觉处理的意义
V Reggie Edgerton,Roland R Roy
V Reggie Edgerton
The lumbosacral spinal cord of mammals contains the neural circuitry capable of generating full weight-bearing locomotion of the hind limbs without any supraspinal input. One or more interventions, for example, pharmacological, epidural sti...
Barbara J Nicklas,Tina E Brinkley
Barbara J Nicklas
Persistent subclinical inflammation predisposes to chronic disease, as well as the development of sarcopenia and disability, in frail elderly. Thus, the inflammatory pathway is a potential target for interventions to reduce aging-related di...
Stephen A Martin,Brandt D Pence,Jeffrey A Woods
Stephen A Martin
Prolonged intense exercise causes immunosuppression, whereas moderate-intensity exercise improves immune function and potentially reduces risk and severity of respiratory viral infections. Here, based on available evidence, we present a mod...
Mark Hargreaves
Mark Hargreaves
Moving toward solid ground on exercise and immune defense against viral infection [0.03%]
运动与抗病毒感染免疫防御的关系需更明确证据支持
Mary P Miles
Mary P Miles
A neuromuscular mechanism of posttraumatic osteoarthritis associated with ACL injury [0.03%]
与前交叉韧带损伤相关的创伤性骨关节炎的神经肌肉机制
Riann M Palmieri-Smith,Abbey C Thomas
Riann M Palmieri-Smith
Anterior cruciate ligament (ACL) injury leads to early-onset osteoarthritis. Quadriceps weakness is a consequence of ACL injury and is considered to result from arthrogenic inhibition (AMI). AMI is the neurological "shutdown" of muscles sur...
High-intensity interval training to maximize cardiac benefits of exercise training? [0.03%]
高强度间歇训练能使运动的心血管效益最大化吗？
Ulrik Wisløff,Øyvind Ellingsen,Ole J Kemi
Ulrik Wisløff
We hypothesized that high-intensity aerobic interval training results in a greater beneficial adaptation of the heart compared with that observed after low-to-moderate exercise intensity. This is supported by recent epidemiological, experim...
Gregory S Sawicki,Cara L Lewis,Daniel P Ferris
Gregory S Sawicki
In humans, a large portion of the mechanical work required for walking comes from muscle-tendons crossing the ankle joint. Elastic energy storage and return in the Achilles tendon during each step enhance the efficiency of ankle muscle-tend...