Exercise for Atrial Fibrillation: Unmasking Comorbidities and Improving Treatment [0.03%]
房颤运动干预：揭露并处理合并症及改善治疗依从性
Jenelle K Dziano,Jonathan P Ariyaratnam,Melissa E Middeldorp et al.
Jenelle K Dziano et al.
Atrial fibrillation is associated with significant symptoms, comorbidities and shared pathophysiological features with heart failure with preserved ejection fraction (HFpEF). We propose that exercise testing, including cardiopulmonary exerc...
Leonard H Epstein,Kyle D Flack,James Roemmich et al.
Leonard H Epstein et al.
Research is needed to understand how to motivate people to be active. There are wide individual differences in the reinforcing value of exercise, which predicts physical activity, and can be increased in sedentary adults. We include a compu...
Augmenting β2-adrenergic signaling during exercise to enhance anti-tumor immune function [0.03%]
运动时增强β2肾上腺素能信号传导可提高抗肿瘤免疫功能
Timothy M Kistner,Emmanuel Katsanis,Richard J Simpson
Timothy M Kistner
Exercise is emerging as a powerful adjuvant therapy during cancer treatment, partly due to its immunomodulatory effects. However, the moderate to vigorous intensities required for optimal immune-boosting effects are a barrier for many patie...
Lyndsey E DuBose,Kerrie L Moreau
Lyndsey E DuBose
Limb Disuse Trials in Humans: Key Insights on Study Design, Ethics, and Project Execution [0.03%]
人体 limbs 不使用试验的设计、伦理及项目实施要点剖析——从关键研究中获得的见解
Matt S Stock,Kylie K Harmon,Justin W Andrushko et al.
Matt S Stock et al.
Limb disuse models, such as immobilization and limb suspension, have been implemented for 30+ years to understand the mechanistic and clinical implications of neuromuscular impairments and muscle atrophy. Drawing on decades of experience, w...
David E Conroy
David E Conroy
Seasonal phase variation, characterized as a sinusoidal waveform anchored at the annual solstices, can be positively associated with both between- and within-person differences in physical activity in observational, longitudinal, and experi...
microRNA-1: A Master Regulator of Metabolism Governing Skeletal Muscle Hypertrophy [0.03%]
微小核糖核酸-1：调控代谢的主调节因子，在骨骼肌肥大中的作用
Jainil Daredia,Benjamin I Burke,John J McCarthy et al.
Jainil Daredia et al.
Downregulation of microRNA-1 (miR-1), the most abundant muscle-enriched microRNA, represents a conserved hallmark of skeletal muscle hypertrophy across species. We propose that mechanical overload-induced reduction in miR-1 expression drive...
Soichi Ando,Toshihiko Fujimoto,Mizuki Sudo et al.
Soichi Ando et al.
Acute physical exercise improves cognitive performance; however, the underlying physiological mechanisms are not yet fully understood. Here, we propose that enhanced neuromodulation is a crucial factor in the exercise-cognition interaction ...
Cognitive neuro-electrical activity during preparation for exercise under hyperthermia [0.03%]
高温环境下运动准备状态的脑电活动及认知效应研究
Manabu Shibasaki,Hiroki Nakata
Manabu Shibasaki
Exercise in a hot environment can impair performance due to not only impaired coordination of major physiological systems but also reduced cognitive processing related to the exercise strategy. In this review, we discuss potential factors c...
Breaking Boundaries Between Resistance and Aerobic Training in Cancer Survivors [0.03%]
癌症幸存者抗阻训练和有氧运动界限的突破
Kyuwan Lee
Kyuwan Lee
Current exercise guidelines for cancer survivors continue to rely on a binary separation of resistance and aerobic training. This review proposes a stimulus-based continuum, in which mechanical load, cardiorespiratory strain, metabolic stre...