UBR5: A New Player in Protein Quality Control for Skeletal Muscle Growth and Remodeling [0.03%]
UBR5：骨骼肌生长和重塑的新调控蛋白参与蛋白质质量控制
David C Hughes,Sue C Bodine
David C Hughes
A balance between protein synthesis and degradation regulates skeletal muscle size. Proteolytic mechanisms, like the ubiquitin-proteasome system, are critical processes in protein quality control. Counterintuitively, the E3 ubiquitin ligase...
Optimizing Female Health: The Crucial Role of Exercise Initiation before and during the Menopausal Transition [0.03%]
优化女性健康：围绝经期前和期间开始锻炼的关键作用
Mette Hansen,Lasse Gliemann,Ylva Hellsten
Mette Hansen
In this review, we hypothesize that delaying physical training initiation until several years after menopause reduces the benefits of exercise on muscle function and cardiovascular health. Early engagement in exercise may counteract the neg...
Exercise to Mitigate Premature Vascular Aging After Doxorubicin Breast Cancer Therapy [0.03%]
运动延缓多柔比星治疗后过早血管衰老的作用研究
Zachary S Clayton,Branden L Nguyen,Ravinandan Venkatasubramanian et al.
Zachary S Clayton et al.
Breast cancer treatment induces a state of premature vascular aging. This article examines the hypothesis that high-intensity interval training may be a time-efficient form of exercise training that effectively mitigates premature vascular ...
Activity Behaviors: Influencers of Cardiometabolic Risk and Adverse Pregnancy Outcomes [0.03%]
行为与心脏代谢风险及不良妊娠结局的关系
Marnie K McLean,Andrea C Kozai,Abbi D Lane
Marnie K McLean
Adverse pregnancy outcomes are linked to excess lifelong cardiometabolic disease risk. Physical activity and sedentary behavior influence risk factors and fluctuate around childbearing. Our overall hypothesis is that improvement in activity...
Hylton B Menz
Hylton B Menz
Foot muscle weakness is a common accompaniment of advancing age and has important functional consequences. However, the merit of foot muscle strengthening programs is yet to be fully demonstrated. The review explores the effect of aging on ...
Silence of the Muscles: Wearable Electromyography, Sitting, and Type 2 Diabetes [0.03%]
肌肉的沉默：可穿戴肌电图、久坐与2型糖尿病
Arto J Pesola,Christian J Brakenridge,Suvi Lamberg et al.
Arto J Pesola et al.
Interrupting prolonged sitting in type 2 diabetes is associated with metabolic and cardiovascular benefits. Wearable electromyography enables precise quantification of the related muscle-excitation patterns. Integrating metabolic and electr...
Pregnancy Loss and Psychological Morbidity: The Potential Role of Exercise [0.03%]
妊娠丢失与心理疾病：运动的潜在作用
Tegan E Hartmann,Danielle Girard
Tegan E Hartmann
Pregnancy loss can result in the development of mental health disorders. There is limited information regarding interventions to prevent and appropriately manage such psychological disorders. Exercise may be a feasible intervention to promo...
Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors [0.03%]
碰撞运动与神经退行性疾病：纳入调停危险因素
Thomas A Buckley,Jaclyn B Caccese,John J Jela
Thomas A Buckley
Collision sport participation with repetitive head impacts has been associated with increased risk of neurodegenerative diseases, but also have lower mortality rates for many individual conditions. The role of modifiable risk factors in lat...
Enhancing Sport-Related Concussion Return-to-Play Protocols for Non-Professional Athletes [0.03%]
提升非职业运动员运动相关脑震荡恢复比赛流程的方案
Hunter Bennett,Joel Garrett,Kerry Peek
Hunter Bennett
After sports-related concussion (SRC), some athletes return before full recovery due to time-based return-to-play recommendations or the masking of symptoms, potentially increasing future injury risk. We hypothesize that current return-to-p...