Evangelos A Christou
Evangelos A Christou
Older adults exhibit greater motor variability, which impairs their accuracy and function, compared with young adults. Low-intensity training that emphasizes muscle coordination reduces variability in older adults. Furthermore, a low amount...
D Walter Wray,Steven K Nishiyama,Anthony J Donato et al.
D Walter Wray et al.
Aging, vascular function, and exercise are thought to have a common link in oxidative stress. Both antioxidant supplementation and exercise training have been identified as interventions that may reduce oxidative stress, but their interacti...
Understanding muscle energetics in locomotion: new modeling and experimental approaches [0.03%]
理解运动中的肌肉能量学：新的建模和实验方法
Brian R Umberger,Jonas Rubenson
Brian R Umberger
Recent estimates of muscle energy consumption during locomotion, based on computational models and muscle blood flow measurements, demonstrate complex patterns of energy use across the gait cycle, which are further complicated when task dem...
Stefan M Duma,Steven Rowson
Stefan M Duma
Priscilla M Clarkson
Priscilla M Clarkson
Thad E Wilson,Craig G Crandall
Thad E Wilson
Whole-body heating decreases pulmonary capillary wedge pressure and cerebral vascular conductance and causes an inotropic shift in the Frank-Starling curve. Whole-body cooling increases pulmonary capillary wedge pressure and cerebral vascul...
Adamantios Arampatzis,Hans Degens,Vasilios Baltzopoulos et al.
Adamantios Arampatzis et al.
Slowing of movement with aging is inevitable. The mechanisms responsible for this deterioration, however, remain poorly understood. Changes to physiological and mechanical factors controlling muscle force and power production seem likely co...
Akshay Sood
Akshay Sood
We have demonstrated in several studies that obesity and adipokines are more strongly associated with asthma in women than in men. The reason for this controversial sex difference is not known. Based on our previous studies, we hypothesize ...
Heat shock proteins are important mediators of skeletal muscle insulin sensitivity [0.03%]
热休克蛋白是骨骼肌胰岛素敏感性的重要调节因子
Paige C Geiger,Anisha A Gupte
Paige C Geiger
Endogenous heat shock proteins (HSP) are decreased in disease states associated with insulin resistance and aging. Induction of HSPs has been shown to decrease oxidative stress, inhibit inflammatory pathways, and enhance metabolic character...
Aging, persistent viral infections, and immunosenescence: can exercise "make space"? [0.03%]
衰老、持续性病毒感染和免疫衰老：运动能“开拓空间”吗？
Richard J Simpson
Richard J Simpson
Overcrowding the immune space with excess clones of viral-specific T cells causes the naïve T-cell repertoire to shrink, which increases infection susceptibility to novel pathogens. Physical exercise preferentially mobilizes senescent T ce...