A High-Fat Diet Aggravates the Age-Related Decline in Skeletal Muscle Structure and Function [0.03%]
高脂饮食加剧骨骼肌结构和功能的年龄相关性衰退
Hans Degens,Anandini Swaminathan,Jason Tallis
Hans Degens
The age-related decline in muscle function is aggravated by a high-fat diet (HFD)-induced increase in fat mass. The hypothesis is that an HFD leads to a faster accumulation of intramyocellular lipids (IMCL) and an earlier onset of muscle dy...
Role of Perivascular Adipose Tissue and Exercise on Arterial Function with Obesity [0.03%]
肥胖对动脉功能的影响及血管周围脂肪组织和运动的作用
Samuel Y Boateng,I Mark Olfert,Paul D Chantler
Samuel Y Boateng
Adipose tissue and arterial dysfunction are common in the obese state. Perivascular adipose tissue (PVAT) plays an important role in mediating arterial health, and with obesity, the PVAT dysfunction negatively affects arterial health. Exerc...
Devin Wahl,Alyssa N Cavalier,Thomas J LaRocca
Devin Wahl
One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly studied "anti-aging" compounds may mimic some effects of exercise on the brain, but novel approaches that target energy-sensing pathways similar to exe...
The S.P.A.C.E Hypothesis: Physical Activity as Medium - Not Medicine - for Public Health Impact [0.03%]
关于身体活动的S.P.A.C.E假设：作为媒介而不是药物产生公共卫生影响
Eduardo Esteban Bustamante,Jared Donald Ramer,María Enid Santiago-Rodríguez et al.
Eduardo Esteban Bustamante et al.
Most scientifically tested physical activity interventions end when research funding ends; interventions that last struggle to sustain benefits. We hypothesize that long-term public health impact will benefit from a shift in how interventio...
Static Stretching Reduces Motoneuron Excitability: The Potential Role of Neuromodulation [0.03%]
静力拉伸降低运动神经元兴奋性及其潜在的神经调节作用
Gabriel S Trajano,Anthony J Blazevich
Gabriel S Trajano
Prolonged static muscle stretching transiently reduces maximal muscle force, and this force loss has a strong neural component. In this review, we discuss the evidence suggesting that stretching reduces the motoneuron's ability to amplify e...
Douglas W Van Pelt,Marcus M Lawrence,Benjamin F Miller et al.
Douglas W Van Pelt et al.
Massage is anecdotally associated with many health benefits, but physiological and clinically relevant mechanisms recently have begun to be investigated in a controlled manner. Herein, we describe research supporting our hypothesis that mas...
Physical Activity and Male Reproductive Function: A New Role for Gamete Mitochondria [0.03%]
体育运动与男性生殖功能：精子线粒体的新角色
Paola Lunetti,Loredana Capobianco,Vincenzo Zara et al.
Paola Lunetti et al.
Several studies demonstrated that some types of physical exercise might affect male reproductive potential, even though the potential mechanisms involved in the modulation of sperm quality remain poorly understood. Therefore, we propose a n...
Pivotal Role of Heart for Orthostasis: Left Ventricular Untwisting Mechanics and Physical Fitness [0.03%]
心脏在直立位维持中的核心作用：左心室解旋机制和体能状况的作用
Shigeki Shibata,Kazukuni Hirabuki,Noritaka Hata et al.
Shigeki Shibata et al.
Augmentation of left ventricular (LV) untwisting due to central hypovolemia is likely to be a compensatory mechanism for maintaining stroke volume, which is reduced by a decrease in cardiac filling during orthostatic stress. Orthostatic int...
Ashley N Oliveira,Brandon J Richards,Mikhaela Slavin et al.
Ashley N Oliveira et al.
Exercise stimulates the biogenesis of mitochondria in muscle. Some literature supports the use of pharmaceuticals to enhance mitochondria as a substitute for exercise. We provide evidence that exercise rejuvenates mitochondrial function, th...