The dual role of ACE2 in viral infections and neurodegeneration: mechanisms and therapeutic opportunities [0.03%]
ACE2在病毒感染和神经退行性病变中的双重作用：机制及治疗机会
Melika Amelimojarad,Mandana Amelimojarad
Melika Amelimojarad
Angiotensin-converting enzyme 2 (ACE2), a key regulator of the renin-angiotensin system (RAS), maintains central nervous system (CNS) homeostasis by metabolizing neuroinflammatory peptides like angiotensin II (Ang II) and apelin-13, thereby...
The protective role of dexmedetomidine against anaesthetics-induced neurotoxicity through downregulating miR-34a [0.03%]
右美托咪啶通过下调miR-34a对抗麻醉剂引起的神经毒性保护作用研究
Ninghao Chen,Bo Wang,Zhenbin Zhan et al.
Ninghao Chen et al.
Spatial and temporal mapping of early alphaherpesvirus invasion routes into the mouse central nervous system [0.03%]
鼠中枢神经系统中早期α疱疹病毒入侵途径的时空映射
Viktoria Korff,Issam El-Debs,Julia Sehl-Ewert
Viktoria Korff
Alphaherpesviruses such as Herpes Simplex Virus 1 (HSV-1) and Pseudorabies virus (PrV) invade the central nervous system (CNS) via peripheral nerves. While olfactory and trigeminal pathways are well-known, additional cranial routes remain u...
Correction: The presence of human polyomavirus JC (JCPyV) in pediatric brain tumors: a plausible trigger in Wnt/β-catenin pathway [0.03%]
关于小儿脑肿瘤中人多瘤病毒JC(JCPyV)的存在：Wnt/ β-连环蛋白通路的可能诱因（纠错）
Sara Passerini,Sara Messina,Marta De Angelis et al.
Sara Passerini et al.
Published Erratum
Journal of neurovirology. 2025 Sep 26. DOI:10.1007/s13365-025-01284-5 2025
The presence of human polyomavirus JC (JCPyV) in pediatric brain tumors: a plausible trigger in Wnt/β-catenin pathway [0.03%]
人多瘤病毒JC(JCPyV)与儿童脑肿瘤关系的初步研究：Wnt/β-连环蛋白信号途径的一个可能触发因素
Sara Passerini,Sara Messina,Marta De Angelis et al.
Sara Passerini et al.
JC polyomavirus (JCPyV) is associated with progressive multifocal leukoencephalopathy (PML), but its plausible role in brain cancers is also disputed. One candidate to mediate cell transformation is the Large T antigen (LTAg), which has the...
Aleksandra Đ Ilić,Vladimir Galić,Vojislava Bugarski Ignjatović et al.
Aleksandra Đ Ilić et al.
COVID-19 is a systemic infection that causes endothelial dysfunction, contributing to severe cases. While vascular complications are well-documented, their impact on vascular structure, function, and cognition remains unclear. This cross-se...
Changes in cerebral function parameters in persons with HIV with symptoms of insomnia switching from dolutegravir- to bictegravir-based antiretroviral therapy [0.03%]
HIV失眠症状患者从多替拉韦换用比克替拉韦抗逆转录病毒治疗后脑功能参数的变化趋势分析
Merle Henderson,Kate Alford,Samira Bouyagoub et al.
Merle Henderson et al.
Sleep disturbances are frequently reported in persons with HIV and have been associated with the use of certain integrase strand transfer inhibitors (INSTIs), such as dolutegravir. This exploratory study assessed changes in cerebral functio...
Sex-specific mitochondrial DNA changes in neuron-derived extracellular vesicles of African American adults: impact of HIV infection and smoking [0.03%]
非洲裔美国人成人神经元衍生外泌体中性别特异性线粒体DNA变化：HIV感染和吸烟的影响
Vladimir Berthaud,Tarik Smith,Venkateswara R Amara et al.
Vladimir Berthaud et al.
Mitochondrial DNA (mtDNA) in extracellular vesicles (EVs) may track HIV-related neuronal injury. We measured mtDNA copy number in neuron-derived EVs (NEVs) and total plasma EVs from 48 African American adults stratified by sex, HIV status, ...
Comment on "Limited HIV-associated neuropathologies and lack of immune activation in sub-saharan African individuals with late-stage subtype C HIV-1 infection" [0.03%]
关于“晚期C型人类免疫缺陷病毒（HIV）感染的撒哈拉以南非洲人中有限的艾滋病相关神经病理学和缺乏免疫活化”的评论
Hinpetch Daungsupawong,Viroj Wiwanitkit
Hinpetch Daungsupawong
Time since HIV diagnosis is linked to amnestic mild cognitive impairment (MCI) in older adults with HIV [0.03%]
HIV感染时间与老年HIV感染者的情景性轻度认知障碍相关
Jason S DeFelice,Mark K Britton,Yancheng Li et al.
Jason S DeFelice et al.
Aging people with HIV (PWH) may be at heightened risk of Mild Cognitive Impairment (MCI), including the subtypes amnestic MCI (aMCI) and non-amnestic MCI (naMCI). We examined associations between putative risk factors (HIV clinical variable...