Impact of late rainy season indoor residual spraying on holoendemic malaria transmission: a cohort study in northern Zambia [0.03%]
雨季晚期室内滞留喷洒对霍洛恩发疟疾传播的影响——赞比亚北部的一个队列研究
Anne C Martin,Mike Chaponda,Mbanga Muleba et al.
Anne C Martin et al.
Background: Indoor residual spraying (IRS) is a malaria control strategy implemented before the rainy season. Nchelenge District, Zambia is a holoendemic setting where IRS has been conducted since 2008 with little impact ...
Candida albicans recovered from persistent candidemia exhibit enhanced virulence traits [0.03%]
从持续性念珠菌血症中分离出的白色念珠菌表现出增强的毒力表型
Felipe de Camargo Ribeiro,Karoline Kristina Kemmerich,Juliana Caparroz Gonçale et al.
Felipe de Camargo Ribeiro et al.
Candida albicans catheter-related candidemia is largely driven by microbial adhesion and biofilm formation on central venous catheters. Cells that disperse from these biofilms can enter the bloodstream, spread to distant organs, and sustain...
Patterns and cofactors of polyfunctional mycobacteria-specific T cell response restoration following 6-month antiretroviral treatment in children living with HIV [0.03%]
接受高效抗逆转录病毒治疗6个月后的HIV感染儿童恢复多效性结核分枝杆菌特异性T细胞反应的模式及协同因子
Cheryl L Day,Irene N Njuguna,Lisa Marie Cranmer et al.
Cheryl L Day et al.
Background: Despite immune restoration after initiation of antiretroviral treatment (ART), the risk of tuberculosis (TB) persists in children living with HIV (CLHIV). We determined patterns of immune restoration of mycoba...
Diversity in Naturally Acquired Immunity to Group B Streptococcus: A Comparative Study of Women from Bangladesh, Malawi, and the United Kingdom [0.03%]
针对不同国家女性自体获得的B群链球菌免疫性的比较研究：来自孟加拉、马拉维和英国的妇女的免疫多样性分析
Shadia Khandaker,Shilpee Sharma,Tom Hall et al.
Shadia Khandaker et al.
Background: Significant disparities in Group B Streptococcus (GBS) colonisation and neonatal disease rates have been documented across different geographical regions. For example, Bangladesh reports notably lower rates co...
Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection [0.03%]
结合潜伏期分布精确估计降雨与军团菌感染之间的关系
Kelsie Cassell,Joshua L Warren,Christopher Heneghen et al.
Kelsie Cassell et al.
Background: Multiple studies have shown a positive relationship between weather events and, 1 to 2 weeks later, Legionnaires' disease (LD) cases. Narrowing this time window of association can help determine whether the me...
Imipenem pharmacokinetics/pharmacodynamics in preclinical hollow fiber model, dose-finding in virtual patients, and clinical evidence of efficacy for Mycobacterium abscessus lung disease [0.03%]
美罗培南药动/药效学、虚拟病人给药选择以及临床有效性的研究：博德特菌属脓肿分枝杆菌所致肺病模型及证据
Sanjay Singh,Tawanda Gumbo,Jann-Yuan Wang et al.
Sanjay Singh et al.
Background: Guideline-based therapy (GBT) for Mycobacterium abscessus (Mab) lung disease achieves sputum culture conversion rates (SCC) of 35%. This poor GBT efficacy is mirrored in the hollow fiber system model of Mab (H...
Sanjay R Mehta,Alan B Wells,Colby Cohen et al.
Sanjay R Mehta et al.
Background: To date, HIV molecular epidemiology (HIV ME) has been primarily used to identify clusters of related infections (cluster detection and response [CDR]) and then address interventions to these clusters. Communit...
Chika Edward Uzoigwe
Chika Edward Uzoigwe
Anelloviruses and Cancer [0.03%]
环状病毒和癌症
Jason Y Tang,Trevor B Chen,Valentina L Kouznetsova et al.
Jason Y Tang et al.
Anelloviruses are among the most prevalent viruses within the human virome, detected in over 90% of healthy individuals. Despite their ubiquity, the role of anelloviruses in human health remains elusive. This review examines the potential a...
Antibody Levels from High-Throughput Variant-Specific SARS-CoV-2 Anti-Spike IgG and ACE2 Neutralization Assays Correlate with COVID Infection Risk in a Large Population [0.03%]
基于高通量变异特异性SARS-CoV-2抗刺突IgG和ACE2中和测定的抗体水平与大规模人群中的COVID感染风险相关性研究
Marni B Jacobs,Alex E Clark,Nicole H Goldhaber et al.
Marni B Jacobs et al.
Background: SARS-CoV-2 antibody levels have been proposed as a correlate of protection (CoP) from infection. Yet, large-scale prospective studies of cost-effective scalable antibody measures as predictors of infection und...