Anti-spike IgG Avidity Enhances Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2: A Prospective Study of Primary Infections and Immunizations [0.03%]
一项关于新型冠状病毒原发感染和免疫接种的前瞻性研究：抗刺突IgG亲和力增强了对严重急性呼吸综合征冠状病毒2型的中和作用
Visa Nurmi,Lea Hedman,Katariina Vapalahti et al.
Visa Nurmi et al.
Background: Immune protection against coronavirus disease 2019 (COVID-19) relies, along with cellular immunity, on anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. We studied the effect of IgG...
Identification and validation of Rhizopus-specific glucoamylase as a novel biomarker for diagnosing mucormycosis [0.03%]
瑞氏毛霉特异性葡萄糖淀粉酶作为诊断黏菌病的新生物标志物的鉴定与验证
Hansraj Choudhary,Harsimran Kaur,Shreya Singh et al.
Hansraj Choudhary et al.
Background: Mucormycosis is a life-threatening invasive fungal infection. Current diagnosis relies on insensitive techniques with prolonged turnaround times, underscoring the need for rapid non-invasive diagnostic tools. ...
Treatment Monitoring and Outcome Prediction in Invasive Aspergillosis using Immunologic Markers [0.03%]
侵袭性曲霉病的免疫学标志物治疗监测及预后判断
Ana Pereira,Jennifer Scott,Andrei Sarlea et al.
Ana Pereira et al.
Background: Invasive aspergillosis (IA) is a leading cause of mortality despite antifungal therapy. Current biomarkers for treatment monitoring and outcome prediction are limited, with host biomarkers showing potential in...
Epitope-Based Multimeric Subunit Vaccine (ATOMSSUISpenta) Confers Broad Protection Against Streptococcus suis Infection [0.03%]
基于抗原表位的多聚亚单位疫苗（ATOMSSUISPENTA）可广谱保护猪免受致病性肺炎链球菌感染
Sun-Young Kim,Fengjia Chen,Woo-Sik Kim et al.
Sun-Young Kim et al.
Background: Streptococcus suis (S. suis) is a zoonotic pathogen that causes severe economic losses in the swine industry and life-threatening infections in humans. The high serotype variability and genomic diversity of S....
Characterization of bronchiolitis and vaccine-induced enhanced respiratory disease in Syrian hamsters caused by respiratory syncytial virus infection [0.03%]
由呼吸道合胞病毒感染引起的叙利亚仓鼠支气管炎和疫苗增强性呼吸系统疾病的特点研究
Binbin Zhao,Gengxin Zhang,Jing Wu et al.
Binbin Zhao et al.
Background: Respiratory syncytial virus (RSV) poses a considerable health burden to pediatric and elderly populations. Vaccine development has been historically challenged by the risk of enhanced respiratory disease (ERD)...
The age-specific concentrations and seroprevalence of antibodies against Salmonella Enteritidis (O:9) and Salmonella Typhimurium (O:4,5) across three sites in Kenya [0.03%]
肯尼亚三个地区抗鸡沙门氏菌（O:9）和抗猪沙门氏菌（O:4，5）的特异浓度及血清学流行率具有年龄特征
Esther M Muthumbi,Sean C Elias,Alfred Mwanzu et al.
Esther M Muthumbi et al.
Background: Seroprevalence studies can indicate the age-distribution of first infection with non-typhoidal Salmonella (NTS) and estimate the rate of infection by age. ...
Rotavirus-specific IgA and IgG Patterns During the First Two Years of Life in the PREVAIL Birth Cohort [0.03%]
PREVAIL出生队列中生命头两年轮状病毒特异性IgA和IgG模式
Julia M Baker,Slavica Mijatovic-Rustempasic,Mary C Casey-Moore et al.
Julia M Baker et al.
Background: Mitigating the underlying causes of differential immunity from rotavirus infection and vaccination requires a comprehensive understanding of rotavirus natural history and immune response. A US-based birth coho...
What's Hot in HIV in 2025-A Basic and Translational Science Review from IDWeek 2025 [0.03%]
2025年HIV热点回顾——来自IDWeek 2025的基础与转化科学研究综述
Ana Rafaela Teixeira,Marina Caskey
Ana Rafaela Teixeira
Advances in basic and translational HIV research have refined our understanding of viral persistence while informing new strategies aimed at prevention and durable virologic control. Here, we present an overview of selected advances in HIV ...
Expelling of P. falciparum sporozoites by Anopheles stephensi mosquitoes during repeated feeding [0.03%]
冈比亚按蚊在反复叮咬时排除间日疟原虫孢子体
Chiara Andolina,Geert-Jan van Gemert,Jordache Ramjith et al.
Chiara Andolina et al.
It is currently unclear whether repeated mosquito feeding attempts achieve pathogen transmission. We measured Plasmodium falciparum sporozoite expelling in Anopheles stephensi mosquitoes during two interrupted feeding attempts. The number o...