Effectiveness of mRNA COVID-19 vaccines and hybrid immunity in preventing SARS-CoV-2 infection and symptomatic COVID-19 among adults in the United States [0.03%]
在美国预防SARS-CoV-2感染和有症状的COVID-19的mRNA新冠疫苗的有效性及其与获得性免疫的联合效果研究：成人中的观察性研究
Leora R Feldstein,Jasmine Ruffin,Ryan E Wiegand et al.
Leora R Feldstein et al.
Background: Understanding protection against SARS-CoV-2 infection by vaccine and hybrid immunity is important for informing public health strategies as new variants emerge. ...
Outbreak of Rotavirus Diarrheal Infection among Adults in King County, Washington, January-June 2023 [0.03%]
华盛顿州国王县2023年1月-6月成人感染轮状病毒腹泻疫情
Jimmy Ma,Raaka G Kumbhakar,Amanda Casto et al.
Jimmy Ma et al.
Rotavirus is a leading cause of diarrhea among children but less known as a cause among adults. We describe clinical, epidemiologic, and genotype characteristics of a rotavirus outbreak among adults in King County, Washington occurring Janu...
Decanoylcarnitine improves liver mitochondrial dysfunction in hepatitis B virus infection by enhancing fatty acid β-oxidation [0.03%]
癸酰肉毒碱通过增强脂肪酸β氧化改善乙型肝炎病毒感染的肝脏线粒体功能障碍
Ye Sun,Qingling Chen,Yuxiao Liu et al.
Ye Sun et al.
Background: The incidence of metabolic-associated steatotic liver disease in patients with chronic hepatitis B is increasing annually; however, the interaction between hepatitis B virus (HBV) infection and lipid metabolis...
Predictive Markers of Incident Tuberculosis in Close Contacts in Brazil and India [0.03%]
巴西和印度结核病密切接触者的发病预测标志物
Betânia M F Nogueira,Francys Rangel,Alice M S Andrade et al.
Betânia M F Nogueira et al.
There are insufficient predictors of progression to tuberculosis among contacts. A case-control study within RePORT-Brazil matched 20 QuantiFERON-positive progressors and 40 non-progressors by sex, age, and exposure duration. Twenty-nine cy...
Cobalt chloride-mimicked hepatocyte cell hypoxia induces TREX1 leading to Hepatitis B virus restriction [0.03%]
氯化钴诱导的肝细胞缺氧通过上调TREX1限制乙肝病毒复制
Rodolphe Suspène,Vincent Caval,Pierre Khalfi et al.
Rodolphe Suspène et al.
Background: Restriction factors are host cell proteins that play a role in limiting virus replication. They form part of the intrinsic immune system and function as a first line of defense against viral infections. Hepati...
Distinguishing Multisystem Inflammatory Syndrome in Children from Typhus Using Artificial Intelligence: MIS-C vs. Endemic Typhus (AI-MET) [0.03%]
利用人工智能区分儿童多系统炎症综合征和地方性斑疹伤寒：MIS-C与地方性斑疹伤寒的鉴别诊断(AI-MET)
Angela Chun,Abraham Bautista-Castillo,Isabella Osuna et al.
Angela Chun et al.
Background: The pandemic emergent disease multisystem inflammatory syndrome in children (MIS-C) following coronavirus disease-19 infection can mimic endemic typhus. We aimed to use artificial intelligence (AI) to develop ...
A surrogate ELISA to select high titer human convalescent plasma for treating immunocompromised patients infected with SARS-CoV-2 variants of concern [0.03%]
选择治疗感染SARS-CoV-2变异株的免疫功能低下患者的高滴度人恢复期血浆的替代ELISA方法
Victoria Dolange,Stefan Slamanig,Adam Abdeljawad et al.
Victoria Dolange et al.
Background: The emergence of new SARS-CoV-2 variants poses a new challenge for the treatment of immunocompromised patients against COVID-19. In this context, high titer COVID-19 Convalescent Plasma (CCP) is one of the few...
Phage-Encoded Virulence Factor, Gp05, Alters Membrane Phospholipids and Reduces Antimicrobial Susceptibility in Methicillin-Resistant Staphylococcus aureus [0.03%]
耐甲氧西林金黄色葡萄球菌噬菌体编码毒力因子Gp05改变细胞膜磷脂组成并降低抗菌药物敏感性
Yi Li,Nagendra N Mishra,Liang Chen et al.
Yi Li et al.
Background: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading pathogen causing severe endovascular infections. The prophage-encoded protein Gp05 has been identified as a critical virulence factor that contri...
A core glycolipid vaccine elicits cross-reactive antibodies against Salmonella spp. and protects against invasive nontyphoidal Salmonella disease in mice [0.03%]
一种核心低聚糖疫苗可诱导针对沙门氏菌的交叉保护性抗体，并可在小鼠中抵御侵袭性非伤寒沙门氏菌病
Scott M Baliban,Surekha Shridhar,Kun Luo et al.
Scott M Baliban et al.
Background: Enteric fever caused by Salmonella enterica serovars Typhi and Paratyphi A in addition to gastroenteritis and invasive disease, predominantly attributable to nontyphoidal Salmonella serovars Typhimurium and En...
Molecular epidemiology of invasive group B Streptococcus in South Africa, 2019-2020 [0.03%]
2019-2020年南非侵袭性B群链球菌的分子流行病学特征
Buhle Ntozini,Sibongile Walaza,Benjamin Metcalf et al.
Buhle Ntozini et al.
Background: Group B Streptococcus (GBS) is a leading cause of neonatal meningitis and sepsis and an important cause of disease in adults. Capsular polysaccharide and protein-based GBS vaccines are currently under developm...