Richard Walker,Robert K M Choy
Richard Walker
Giuditta Annibaldis,Barré Soropogui,Kékoura Ifono et al.
Giuditta Annibaldis et al.
Background: Lassa fever (LF) is endemic in Guinea, with high seroprevalence in the forest region. However, clinical cases have been only anecdotally reported. In August 2022, a nosocomial outbreak occurred at a private cl...
A New Type of Nonsuppressible Viremia Produced by HIV-Infected Macrophage [0.03%]
一种由HIV感染的巨噬细胞引起的新型非抑制病毒血症
Matthew J Moeser,Olivia D Council,Nathan Long et al.
Matthew J Moeser et al.
Background: HIV-1 RNA typically declines rapidly after initiation of antiretroviral therapy (ART), often reaching undetectable levels within a few weeks and remaining undetectable by standard assays. However, some patient...
Development of an experimental human blood-stage model for studying Plasmodium knowlesi [0.03%]
建立一个实验性的人体血液阶段模型以研究知氏疟原虫
Jeremy S E Gower,Rebecca Webster,Jacob A F Westaway et al.
Jeremy S E Gower et al.
Background: The zoonotic parasite Plasmodium knowlesi is an increasing cause of human malaria in Southeast Asia. We aimed to develop a P. knowlesi induced blood-stage malaria (IBSM) model to facilitate study of parasite b...
Jonathan Spector,Kurt Hanevik,Poonum Korpe et al.
Jonathan Spector et al.
Cryptosporidiosis is a major cause of parasitic diarrhea in lower income countries disproportionately affecting young children, malnourished populations, and people with compromised immunity. While still underemphasized on the global health...
Evaluation of serum antibodies as correlates of protection against norovirus infection and disease [0.03%]
评估血清抗体作为诺如病毒感染和疾病的保护相关因素
Savannah L Miller,W Zane Billings,Murphy John et al.
Savannah L Miller et al.
Background: Norovirus is a major cause of acute gastroenteritis. Several vaccines are in development. Identifying a reliable immunological correlate of protection (CoP) would aid vaccine development and evaluation; howeve...
Effective Treatment using Bumped Kinase Inhibitor 1708 in a Calf Clinical Model of Cryptosporidiosis [0.03%]
一种有效的治疗隐孢子虫病的方法——用Bumped kinase抑制剂1708治疗犊牛隐孢子虫病模型实验
Deborah A Schaefer,Dana P Betzer,Kevin Ackman et al.
Deborah A Schaefer et al.
Cryptosporidium parvum, an apicomplexan parasite and the causative agent of cryptosporidiosis, contributes to a high burden in mortality and morbidity for humans and livestock. Currently, there are no reliably successful parasite-specific t...
Cryptosporidium parvum outbreak among volunteers of a licensed wildlife rehabilitation center housing raccoons-2024 [0.03%]
2024年在一家收容浣熊的licensed野生动物康复中心志愿人员中爆发的小隐孢子虫病疫情
Shanna Miko,Connie Austin,Barbara L Smith et al.
Shanna Miko et al.
Zoonotic transmission of Cryptosporidium parvum (C. parvum) is often associated with ruminants. We report an investigation of cryptosporidiosis among persons who had contact with raccoons. In July 2024, two states identified 18 human crypto...
First report on remdesivir use for the treatment of respiratory syncytial virus in five allogeneic hematopoietic cell transplant recipients [0.03%]
首个瑞德西韦治疗5例异基因造血干细胞移植后呼吸道合胞病毒感染患者的报道
Denise J McCulloch,Fareed Khawaja,Frank P Tverdek et al.
Denise J McCulloch et al.
Respiratory syncytial virus (RSV) infection causes substantial morbidity among hematopoietic cell transplant (HCT) patients and lacks approved therapies. Remdesivir demonstrates antiviral activity in vitro, but data in humans are lacking. W...