Cryptosporidiosis in inborn errors of immunity: a single center cohort and review of the literature [0.03%]
遗传性免疫缺陷病患者的隐孢子虫感染:单中心病例系列及文献复习
Chen Wang,Evgenii Filippov,Amir Seyedmousavi et al.
Chen Wang et al.
Background: Severe intestinal or hepatobiliary cryptosporidiosis affects patients with inborn errors of immunity (IEI), particularly those with CD40 ligand or CD40 deficiency, major histocompatibility complex class II def...
Epidemiology, resistance and virulence of neonatal Klebsiella pneumoniae isolates from a tertiary hospital in Tanzania [0.03%]
坦桑尼亚一家三级医院新生儿肺炎克雷伯菌的流行病学、耐药性和毒力研究
Delfina R Msanga,Caroline A Minja,Christoph Härtel et al.
Delfina R Msanga et al.
Background: Klebsiella pneumoniae (Kp) is a cause of blood stream infections (BSI) in neonates and poses a major clinical challenge. Hence, we aimed to investigate molecular epidemiology, transmission dynamics and underly...
Diagnostic Accuracy of Commercial Large Language Models for Anogenital Skin Lesion Images: A Comparative Study of Gemini, Claude and ChatGPT [0.03%]
商业大型语言模型对生殖器皮肤病变图像诊断准确性的比较研究:Gemini、Claude和ChatGPT的对比分析
Nyi Nyi Soe,Phyu Mon Latt,David Lee et al.
Nyi Nyi Soe et al.
Background: Diagnosing anogenital dermatological conditions often requires specialist expertise that is unavailable in many clinical settings. Large language models (LLMs) are increasingly accessible to clinicians, but th...
Assessing the effect of malaria exposure history on tetanus antibody waning rates among children in Jinja and Tororo Districts, Uganda [0.03%]
乌干达金贾和托罗罗地区的儿童麻疹暴露史对其破伤风抗体消退率的影响评估研究
Alyssa N Sbarra,Will Stone,Kevin Tetteh et al.
Alyssa N Sbarra et al.
Background: Malaria causes immune perturbations and has been shown to affect immunogenicity to vaccine-preventable diseases. It is unknown, however, how repeated malaria infections affect the duration of vaccine protectio...
Postnatal Cytomegalovirus Infection in Preterm Infants ≤28 Weeks: Maternal IgG Effector Function, Risk Factors, Viral Kinetics in Relation to Symptom Onset, and Clinical Outcomes in a Prospective Multicenter Study [0.03%]
一项前瞻性多中心研究:母亲IgG效应功能、先天性巨细胞病毒感染早产儿(≤28周)的风险因素、病毒动力学及其与症状出现的关系和临床结局
Yuichiro Sugiyama,Juri Koizumi,Hiroki Kondo et al.
Yuichiro Sugiyama et al.
Background: Postnatal cytomegalovirus (pCMV) infection is a major concern in extremely preterm infants. However, the clinical and maternal immunological factors involved in pCMV transmission and related manifestations rem...
Modeling predicts shortening of DAA treatment duration to 5 weeks in individuals with recent or chronic infection with HCV RNA negativity at day 7 on treatment [0.03%]
建模预测直接抗丙型肝炎病毒药物治疗持续时间缩短至5周(以治疗第7天检测不到丙型肝炎病毒RNA为依据)
Ashish Goyal,Scott J Cotler,Gail V Matthews et al.
Ashish Goyal et al.
Background: Identifying individuals with hepatitis C virus (HCV) infection who could be cured with a shorter duration of direct-acting antivirals (DAA) therapy would support the effort to reach HCV elimination goals. To d...
Increased in-hospital mortality in immunocompromised individuals hospitalized with COVID-19 during the global pandemic, a multinational cohort study in the EuCARE project [0.03%]
全球大流行期间免疫功能低下且因COVID-19住院患者的病死率增加——EuCARE项目中的一项多国队列研究
Ashley O Roen,Pontus Hedberg,Joana P Ventura Pereira et al.
Ashley O Roen et al.
Background: Although COVID-19 is no longer a public health emergency, it remains the most prevalent circulating infectious-like-illness in Europe. Whether immunocompromising conditions (ICCs) still carry increased mortali...
Declining efficacy of moxifloxacin for Mycoplasma genitalium infection: time for fluoroquinolone-resistance guided therapy? [0.03%]
摩灭利星治疗解脲支原体感染效果下降:应采用根据耐药性指导的疗法吗?
Laura G Matthews,Lenka A Vodstrcil,Natasha L Wild et al.
Laura G Matthews et al.
Background: We assessed trends in moxifloxacin-use and efficacy for MG over a decade at Melbourne Sexual Health Centre (MSHC). Specific Mycoplasma genitalium (MG) mutations, namely ParC-S83I, have been associated with mox...
A missed early signal of the HIV-tuberculosis syndemic in a 1982 MMWR report [0.03%]
艾滋病与结核病合并流行病的早期信号被忽视——1982年MMWR报告分析
Arthur E Pitchenik
Arthur E Pitchenik
Host plasma protein biomarkers for tuberculosis disease screening in febrile adults in Tanzania [0.03%]
坦桑尼亚发热成人肺结核病的血浆蛋白质生物标志物筛查研究
Michael Prodanuk,Noemie Boillat-Blanco,Valérie DAcremont et al.
Michael Prodanuk et al.
Background: Host circulating biomarkers may enhance access to tuberculosis (TB) diagnostics in low-resource settings. We sought to identify host plasma proteins that differentiate TB disease from other infectious causes o...