Unexpected Cryptosporidium species Identified from New York State Clinical Stool Specimens [0.03%]
纽约州临床粪便标本中意外鉴定出的隐孢子虫种群
Kimberly Mergen,Erica Lasek-Nesselquist,Amy E Robbins et al.
Kimberly Mergen et al.
Background: Cryptosporidiosis is predominantly considered a waterborne illness that occurs after becoming infected with Cryptosporidium parvum or Cryptosporidium hominis, the two species that typically infect humans. Howe...
Persistence and local maintenance of STLV-1 infection in the vaginal epithelium of postmenopausal Japanese macaques [0.03%]
日本猕猴绝经后阴道上皮组织中STLV-1的持续感染和局部维持
Yohei Seki,Mami Uemura,Kenta Tezuka et al.
Yohei Seki et al.
Background: Human T-cell leukemia virus type 1 (HTLV-1) and simian T-cell leukemia virus type 1 (STLV-1) primarily infect CD4+ T-cells and spread via cell-to-cell contact in vivo. However, the mechanism underlying viral e...
Cell-Mediated Immunity of mRNA-1283 Vaccine Encoding SARS-CoV-2 Spike Receptor-Binding and N-Terminal Domains in Preclinical and Clinical Studies [0.03%]
针对SARS-CoV-2刺突受体结合域和N端结构域的mRNA疫苗（MRNA-1273）在临床前研究和临床试验中的细胞介导免疫反应
Alec W Freyn,Yadunanda Budigi,Bethany Girard et al.
Alec W Freyn et al.
Background: Cell-mediated immunity contributes to durable protection against COVID-19. mRNA-1283 vaccine, encoding the receptor-binding and N-terminal domains of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-C...
Immunogenicity of a Bivalent Typhoid-Paratyphoid Conjugate Vaccine Against Diverse Salmonella Paratyphi A Isolates [0.03%]
双价伤寒副伤寒结合疫苗对多种鼠伤寒沙门氏菌分离株免疫原性的评价
Martina Carducci,Eleanna Sarakinou,Luisa Massai et al.
Martina Carducci et al.
Background: In a first-in-human phase-1, randomized, controlled trial, a bivalent conjugate vaccine (Vi-CRM197+O:2 CRM197) elicited robust IgG and bactericidal activity against vaccine-homologous Salmonella Paratyphi A st...
How to Fight for Immunization When Vaccine Skeptics Are Calling the Shots [0.03%]
面对疫苗怀疑论者当道，我们该如何是好？
Kristin Goddard,Mallory K Ellingson,Noel T Brewer
Kristin Goddard
Harika Kalangi
Harika Kalangi
IgM/IgA-Enriched Immunoglobulins: a Key to Breaking the Cycle of Clostridioides difficile Infection Recurrences in Patients with Hypogammaglobulinemia? [0.03%]
富含IgM/IgA的免疫球蛋白：打破低丙种球蛋白血症患者艰难梭菌感染复发周期的关键？
Benjamin Coiffard,Alexandre Brodovitch,Jean-Louis Mège et al.
Benjamin Coiffard et al.
We present the case of a 57-year-old woman with secondary hypogammaglobulinemia who experienced Clostridioides difficile infection, with repeated recurrences despite transient clinical responses to standard therapies, including repeated fec...
Clinical and analytical evaluation of a commercial Aspergillus fumigatus real-time PCR assay for the diagnosis of invasive pulmonary aspergillosis in patients with hematological malignancies [0.03%]
侵袭性肺曲霉病商业实时聚合酶链反应检测在血液系统恶性肿瘤患者中的临床与分析评估研究
Charles Gibert,Jeanne Bigot,Eolia Brissot et al.
Charles Gibert et al.
Background: Invasive pulmonary aspergillosis (IPA) is a severe complication of hematological malignancies. The European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research ...
Risk of hospitalization related to influenza A(H3N2) virus subclade K, Thailand, June-December 2025 [0.03%]
2025年6月至12月泰国流感A(H3N2)病毒亚谱系K相关的住院风险
Kriengkrai Prasert,Prabda Praphasiri,Darunee Ditsungnoen et al.
Kriengkrai Prasert et al.
Antigenically drifted influenza A(H3N2) subclade K viruses have contributed substantially to influenza burden since 2025, but their clinical severity is less well described. Using sentinel surveillance data from Thailand, we found no signif...
Chikungunya Vaccines for Travelers: Unanswered Pragmatic Questions Persist [0.03%]
出行者的登格热疫苗：实际问题仍然没有答案
David O Freedman
David O Freedman