Xingcan Fan,Tao Yu,Qiuyu Liao et al.
Xingcan Fan et al.
T cell receptor-engineered T cell (TCR-T) therapy represents an innovative tumor immunotherapy. Distinct from CAR-T, it recognizes MHC-restricted antigens to target tumor-specific antigens, exhibiting unique advantages for both solid and he...
American Radium Society (ARS) Appropriate Use Criteria (AUC) for Low-Dose Radiotherapy for Treatment of Osteoarthritis [0.03%]
美国镭学协会(LDR治疗骨关节炎适当使用标准)
Austin Dove,Bobby Koneru,William Small Jr et al.
Austin Dove et al.
Objectives: To summarize current evidence for radiotherapy in the treatment of OA. The population, intervention, comparator, and outcome questions included: What is the role of LDRT for treatment of OA?; What are risks of...
Comorbidity Burden, Treatment, and Survival Among Screen-Detected Lung Cancer Patients: Implications for USPSTF Guidelines [0.03%]
基于人群筛查的肺癌患者伴发疾病负担、治疗及生存状况对美国预防服务工作组指南的意义
Norah Powell,Madeleine Hinojos,Shruti Ayyalasomayajula et al.
Norah Powell et al.
Objectives: Current US Preventive Services Task Force (USPSTF) guidelines for lung cancer screening restrict low-dose chest CT (LDCT) eligibility to those willing to undergo surgery. Little is known about comorbidities, t...
Outcomes With Immunotherapy in Hormone Receptor-Positive Breast Cancer: A Systematic Review and Meta-Analysis [0.03%]
免疫疗法治疗激素受体阳性乳腺癌的疗效：系统性回顾和meta分析
Moazzam Shahzad,Muhammad K Amin,Amir Kasaeian et al.
Moazzam Shahzad et al.
Objectives: Hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer has historically shown limited response to immunotherapy. We conducted a systematic review and meta-analy...
Combination of Ponatinib and Blinatumomab in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: A Systematic Review and Meta-Analysis [0.03%]
ponatinib与blinatumomab联合治疗费城染色体阳性急性淋巴细胞白血病的系统评价和 meta 分析
Faiza Fatima,Anurag Jha,Ahmed Raza et al.
Faiza Fatima et al.
Objectives: Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) is traditionally treated with tyrosine kinase inhibitors (TKIs) alongside chemotherapy. Recent studies suggest that combining ponatinib a...
Early Detection of Colorectal Cancer Following Changes to Screening Guidelines: A Population-Based Analysis of Adults Aged 45 to 49 [0.03%]
筛查指南更新后结直肠癌发病率的变化——一项关于45-49岁成人队列的研究
Boniface Mensah,Albert E Orhin,Natalie A Y Akoto et al.
Boniface Mensah et al.
Objectives: Colorectal cancer (CRC) is the third most common cancer, with millions of new cases and deaths annually. There is an increasing incidence of CRC among patients
Efficacy of Fibroblast Growth Factor Receptor Inhibitors (FGFRi) in Locally Advanced or Metastatic Cholangiocarcinoma With FGFR Fusions or Rearrangements: A Meta-Analysis of Clinical Trials [0.03%]
成纤维细胞生长因子受体抑制剂治疗具有FGFR融合或重排的局部晚期或转移性胆管癌疗效的临床试验Meta分析
Abdul Rehman,Jacopo Lin,Sakshi Arora et al.
Abdul Rehman et al.
Objectives: The efficacy of various FGFR inhibitors (FGFRi) has been reported for advanced cholangiocarcinoma patients harboring FGFR fusion genes or rearrangements. However, the pooled efficacy of FGFRi is still lacking....
Sharan Shanubhogue,Shravani Reddy,Ruksana Sidhique P R et al.
Sharan Shanubhogue et al.
Pediatric oncological emergencies are acute, life-threatening complications arising from malignancies or their treatment. Prompt recognition and intervention are essential to prevent significant morbidity and mortality. Pediatric oncologica...
Divergent Biliary Tract Cancer Trajectories: ARIMA Forecasting Reveals Alarming 2030 Projections With Distinct Gender-Stratified Epidemiology in Asian Countries [0.03%]
分化的胆道癌轨迹：ARIMA预测显示亚洲国家2030年的惊人预测及性别分层流行病学特征不同
Saikat Mandal,Manideepa Maji,Arkadeep Dhali
Saikat Mandal
Cholangiocarcinoma (CCA) and gallbladder cancer demonstrate profoundly divergent epidemiological trajectories across 2 decades (2003 to 2017), demanding urgent investigation. Population-based registry data from the cancer incidence in 5 con...
A Pilot Feasibility and Acceptability Study of a Structured Nurse-Led Family Caregiver Program Among Caregivers of Hospitalized Cancer Patients [0.03%]
一项针对住院癌症患者家属照护者的结构化护士主导的照护者计划的可行性与可接受性试点研究
James Raj K,Preeti R Bhupali
James Raj K
Introduction: Family caregivers of hospitalized cancer patients play a vital role in supporting patient care, but often experience considerable burden, stress, and reduced quality of life due to limited preparation and a ...