Sex Disparities in Postoperative Outcomes Among Patients With Spine Tumors: A Systematic Review [0.03%]
脊柱肿瘤患者的术后结局性别差异：系统回顾
Tobechukwu Ndika,Anushka Peer,Kristina Schaufele et al.
Tobechukwu Ndika et al.
Objectives: Sex-based differences in postoperative outcomes have been reported in nononcologic spine surgery, but their impact among patients undergoing surgery for spine tumors remains poorly understood. We conducted a s...
Outcomes and Toxicities of Radiation Therapy in HIV-Positive Patients With Head and Neck Cancer: A Systematic Review [0.03%]
HIV阳性头颈部肿瘤患者放射治疗的效果和毒性：系统性综述
Linden A Lechner,Florence Mutua,Vivek Ghosh et al.
Linden A Lechner et al.
People living with HIV (PLWH) have an increased incidence of head and neck cancer (HNC), yet the impact of HIV on radiation therapy (RT) outcomes remains poorly defined. To our knowledge, no prior systematic review has synthesized this evid...
Anaplastic Thyroid Carcinoma in the Modern Era: A Population-Based Provincial Analysis [0.03%]
现代时代的甲状腺未分化癌：基于人口的省级分析
Lindsay Barr,Richard Musoke,Alexa Dang et al.
Lindsay Barr et al.
Objectives: Anaplastic thyroid carcinoma (ATC) is a rare and aggressive malignancy. The purpose of this study was to update the outcomes of ATC in a large provincial database in a modern cohort. ...
Vitamin C as an Adjunctive Therapy in Cancer: A Systematic Review and Meta-Analysis of Outcomes in Solid and Hematologic Malignancies [0.03%]
维生素C作为癌症辅助治疗的系统评价和Meta分析：实体瘤与血液系统恶性肿瘤的预后不同
Moazzam Shahzad,Muhammad Kashif Amin,Hafiz Muhammad Hannan Javed et al.
Moazzam Shahzad et al.
Objectives: Vitamin C has gained interest as an adjunctive treatment in oncology due to its antioxidant effects, potential to enhance cancer therapy, and ability to improve quality of life. This systematic review and meta...
PD-1 Inhibition With Camrelizumab in Cervical Cancer: A Systematic Review and Meta-Analysis [0.03%]
卡瑞利珠单抗用于治疗宫颈癌的PD-1抑制作用：系统性回顾和荟萃分析
Adeena Musheer,Muhammad S Mannan,Muhammad W Khan et al.
Adeena Musheer et al.
Objectives: Cervical cancer is the fourth leading cause of cancer mortality in women worldwide. PD-L1 is expressed in 34.4% to 96% of cervical cancers. Camrelizumab is an anti-PD-1 IgG4 antibody with antitumor activity. T...
Targeting HCC With SBRT: Practical Strategies and Immunologic Synergies [0.03%]
立体定向体外放射治疗结合免疫检查点抑制剂治疗肝细胞癌：实用策略和免疫协同效应
Vedin Barve,Neil Newman
Vedin Barve
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, characterized by high recurrence rates despite curative-intent therapies. While surgical resection, ablation, transarterial therapies, and systemi...
Safety and Efficacy of Palbociclib and Endocrine Therapy Versus Endocrine Therapy Alone in HR+/HER 2- Breast Cancer Patients; a Systematic Review and Meta-Analysis [0.03%]
帕博西尼联合内分泌治疗与单纯内分泌治疗HR+/HER 2-乳腺癌患者的疗效和安全性：系统评价和 meta 分析
Faiza Fatima,Muhammad I Bhatti,Ahmed Raza et al.
Faiza Fatima et al.
Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have emerged as novel agents in the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer. Palbociclib, w...
Real-World Outcomes of Adjuvant Immunotherapy and Radiation Therapy for Stage III Merkel Cell Carcinoma [0.03%]
III期默克尔细胞癌术后免疫治疗与放疗的预后研究
Natalie N Chakraborty,Trisha Lal,Iris Sheng et al.
Natalie N Chakraborty et al.
Objectives: Immune checkpoint inhibitors demonstrate meaningful promise in advanced unresectable Merkel cell carcinoma (MCC), but their role in the adjuvant setting is evolving. We assessed the association between adjuvan...
Hepatobiliary Toxicity Following Ablative Radiation for Centrally Located Hepatocellular Carcinoma [0.03%]
中心型原发性肝癌根治性放疗的肝胆毒性分析
Sarah Feldkamp,Bailey Nelson,Kyle Wang et al.
Sarah Feldkamp et al.
Objectives: Centrally located hepatocellular carcinoma (CL-HCC) poses a therapeutic challenge due to proximity to the central hepatobiliary tract (cHBT) and concern for radiation-related toxicity. We evaluated hepatobilia...
Targeted CysLTR1 Blockade Rescues Myeloid-Mediated Resistance to Immune Checkpoint Inhibition in Solid Malignancies: A Combined Genomic, Emulated Clinical Trial, and Epidemiological Negative-Control Analysis [0.03%]
针对实体瘤中髓系细胞介导的免疫检查点抑制抵抗的治疗：结合基因组、模拟临床试验和流行病学阴性对照分析发现CysLTR1阻断可改善抗肿瘤免疫响应
Steven Lehrer,Peter Rheinstein
Steven Lehrer
Objectives: Myeloid-driven inflammation contributes to resistance to immune checkpoint inhibitors (ICIs) in solid tumors, partly through neutrophil-mediated immunosuppressive mechanisms. Experimental evidence suggests cys...