Treponemal and Lipoidal IgM Tests in the Diagnosis and Management of Syphilis Among Nonpregnant Adults: A Systematic Review [0.03%]
非孕妇梅毒诊断与治疗中的梅毒螺旋体和脂质IgM检测：一项系统性综述
Zachary W Lorenz,Michael E McCarthy,Susan Tuddenham et al.
Zachary W Lorenz et al.
There are many commercially available tests that isolate immunoglobulin M (IgM) antibodies to either treponemal-specific or lipoidal (nontreponemal) antigens. These IgM tests for syphilis are distinct from standard serologies that are routi...
Implementation of Nursing Protocols for Penicillin-allergy Assessment in an STI Clinic [0.03%]
性病门诊中实施青霉素过敏评估护理方案的落实
Jessica W Dalby,Helen Hermus,Sharon Conley et al.
Jessica W Dalby et al.
Penicillin allergy assessment within STI clinics is critical for timely, safe, and effective syphilis treatment among marginalized populations who experience multiple barriers to care. It is also an important public health measure to suppor...
Estimating Excess Mortality Among People Living with HIV/AIDS During the COVID-19 Pandemic in the USA [0.03%]
美国艾滋病毒/艾滋病患者在COVID-19大流行期间的超额死亡估算
Lindsay M Hall,Hamed Karami,Gerardo Chowell
Lindsay M Hall
Background: Understanding syndemic effects of COVID-19 and HIV/AIDS can inform future public health preparedness. This study quantifies the all-cause excess death rate of people living with HIV/AIDS (PWHA) during the 2020...
Randomized Study of Usual Care vs Xpert® Xpress MVP at the Point of Care for Accurate Diagnosis and Appropriate Treatment of Vaginal Infections [0.03%]
常规护理与在检验科进行Xpert® Xpress MVP检测以准确诊断和合理治疗阴道感染的随机对照研究
Sharon L Hillier,Ingrid Macio,Rachel Gallagher et al.
Sharon L Hillier et al.
Background: Accuracy of vaginitis diagnoses in usual care varies. This study (clinicaltrials.gov NCT06438575) evaluated the clinical utility of Xpert ® Xpress MVP, a CLIA-waived nucleic acid amplification test (NAAT), fo...
Nicole L Gallaway,David A Jackson,Elizabeth Torrone
Nicole L Gallaway
Timely treatment of syphilis is key to interrupting transmission and preventing sequelae. We calculated treatment timeliness for reported syphilis cases in the US in 2023. Most case notifications (85.6%) had documentation of starting treatm...
Use of Herpes Simplex Virus Type-1 and Type-2 Antibody Tests for Targeted Screening for Genital Herpes [0.03%]
用于针对性筛查生殖器疱疹的一型和二型单纯疱疹病毒抗体检测的应用
Lao-Tzu Allan-Blitz,Gary A Richwald,Jeffrey D Klausner
Lao-Tzu Allan-Blitz
Genital herpes diagnoses with connecting pharmacological prescriptions among enrollees 18 years and older in a large employer-based healthcare claims data, United States, 2019-2023 [0.03%]
美国大型雇主基于医疗保健理赔数据中18岁及以上参保人的生殖器疱疹诊断及相应的药物处方连接情况（2019-2023年）
Brian Emerson,Sancta B St Cyr,Guoyu Tao
Brian Emerson
Objectives: Genital herpes (GH) is caused by herpes simplex type 1 and type 2. GH affects 500 million people worldwide and is often managed with pharmaceutical therapies, counseling, and education. We examined diagnosed G...
Effective Alternative Treatment Regimens for People with Infectious Syphilis: A Systematic Review and Network Meta-Analysis [0.03%]
感染性梅毒患者的高效替代治疗方案：系统评价和网状Meta分析
Anna Cvetkovic,Laura Erdman,Rochelle Johnstone et al.
Anna Cvetkovic et al.
Background: Given increasing rates of syphilis and shortages of the first-line agent benzathine penicillin, alternative treatment options are needed. This systematic review examined the existing evidence for alternative t...
Implementation, Feasibility and Acceptability of Reflex Molecular Antibiotic Resistance Testing for Treatment Diversification of N. gonorrhoeae in a Sexual Health Clinic [0.03%]
基于性传播疾病门诊的奈瑟氏淋病菌抗生素耐药分子检测的效果、可行性和可接受度研究
Stephanie E McLaughlin,Katherine Holzhauer,Matthew R Golden et al.
Stephanie E McLaughlin et al.
Background: Resistance-guided treatment has the potential to expand treatment options for Neisseria gonorrhoeae (NG) and may be useful as an antimicrobial stewardship strategy. ...
An exploratory intersectional analysis of lifetime syphilis prevalence among people who inject drugs in Montreal, Canada [0.03%]
加拿大蒙特利尔注射吸毒者一生中梅毒患病率的探索性交叉分析研究
Brendan L Harney,Julie Bruneau,Valérie Martel-Laferrière et al.
Brendan L Harney et al.
Background: Syphilis cases have increased among women and heterosexual men in Canada and people who inject drugs (PWID) are an emerging group at risk of infection. We aimed to examine syphilis prevalence among PWID strati...