Successful Treatment of Highly Resistant Trichomoniasis with Tinidazole and Paromomycin Regimen after Boric Acid failure [0.03%]
硼酸治疗失败后的替硝唑和巴龙霉素联合疗法成功治疗耐药的滴虫感染
Karley Dutra,Paul Nyirjesy
Karley Dutra
Metronidazole and tinidazole resistance with Trichomonas vaginalis is increasing. Paromomycin cream with high dose tinidazole is effective, though vulvovaginal ulceration has limited its use. We describe two patients who failed high dose ti...
HIV PrEP Knowledge and Prescribing Patterns Among Healthcare Providers in Southwestern Pennsylvania [0.03%]
南宾夕法尼亚州医疗保健提供者对HIV 预防知识和处方模式的调查
Benjamin L Hamel,Elizabeth L Klusman,Emma E Seagle Roth et al.
Benjamin L Hamel et al.
Background: Despite the proven effectiveness of HIV pre‑exposure prophylaxis (PrEP), uptake remains suboptimal, and provider‑level barriers have been shown to impede implementation. Southwestern Pennsylvania, including ...
Implementation of a chart flag to improve linkage to care after emergency department syphilis diagnosis [0.03%]
急诊梅毒诊断后改善转介接受治疗的图表标志实施研究
Jackson Montgomery,Joseph Mason,Eleanor Friedman et al.
Jackson Montgomery et al.
A retrospective review of patients requiring outreach for syphilis results after emergency department (ED) screening showed that adding a chart flag to address results at return ED visits for patients otherwise unable to be contacted result...
Sexual Behaviors of Dating Apps Users: A Descriptive Study in French Population [0.03%]
法国人口 dating App 用户的性行为描述性研究
Alexandre Grigolet,Emmanuel Prothon,Hugo Guillermou et al.
Alexandre Grigolet et al.
Background: Sexually transmitted infections (STIs) remain a major public health concern with rising incidence worldwide. Dating applications have reshaped partner acquisition and sexual networking patterns, yet data on Fr...
Unknown Duration or Late Syphilis Cases with High Titers - North Carolina, 2015 & 2023 [0.03%]
未知病期或梅毒晚期病例（滴度较高）——北卡罗来纳州，2015年和2023年
Daniel J Gore,David A Jackson,Elizabeth Torrone et al.
Daniel J Gore et al.
Background: While recent national increases in unknown duration or late syphilis (UDLS) have outpaced diagnoses of earlier stages of syphilis, causes and contributors remain unknown. We evaluated changes in the proportion...
A New Era in Treponema pallidum Cultivation: Current Advances and Future Directions [0.03%]
梅毒螺旋体培养的新时代：当前进展和未来方向
Kelly L Hawley,Linda Grillová,Lorenzo Giacani et al.
Kelly L Hawley et al.
Although long-term in vitro cultivation of the syphilis agent, Treponema pallidum subspecies pallidum, was introduced less than a decade ago, it has revolutionized and accelerated research with this difficult pathogen. Moreover, it is allow...
Lorenzo Giacani,Caroline E Cameron,Feijun Zhao et al.
Lorenzo Giacani et al.
In the last decade, we have witnessed outstanding scientific advances towards the development of a globally efficacious syphilis vaccine. This manuscript summarizes information presented at the Shanghai International Syphilis Symposium (Oct...
Potential Strategies for Participation and Community Engagement in Syphilis Clinical Research [0.03%]
梅毒临床研究参与和社区参与的潜在策略
Mitch M Matoga,Suzanne Day,Dan Wu et al.
Mitch M Matoga et al.
Ethical abuses related to syphilis research have led to significant barriers to implementation of syphilis clinical trials. Insights from an expert meeting included ways to actively involve participants in clinical research, considerations ...
Evaluation of Partner Notification Strategies to Improve Syphilis Management in Pregnancy in Blantyre, Malawi: A Mixed-Methods Study [0.03%]
混合方法研究评估马拉维布兰太尔孕期梅毒管理改善的伴侣通知策略有效性
Kondwani Kaitume Kaunda,Deirdre J Foley,Michael Marks et al.
Kondwani Kaitume Kaunda et al.
Background: Congenital syphilis remains a major global health challenge, driven partly by maternal reinfection during pregnancy. Partner notification (PN) is critical to prevent reinfection and reduce mother-to-child tran...
Innovations and Challenges in Syphilis Screening and Prevention Among Men Who Have Sex With Men: A Scoping Review [0.03%]
MSM中梅毒筛查和预防的创新与挑战：系统综述
Mariam Assi,Kimberly A Workowski,Leandro A Mena
Mariam Assi
Syphilis rates among men who have sex with men have risen sharply worldwide, reflecting evolving sexual networks, persistent gaps in screening and care, and behavioral changes that have accompanied the broader uptake of HIV preexposure prop...