Lisa Frigati,Laurens Manning,Michael Marks et al.
Lisa Frigati et al.
For more than 70 years, penicillin has remained the cornerstone of treatment for syphilis. While penicillin remains highly effective, there is a pressing need to develop new therapeutic options driven both by ongoing challenges in the suppl...
The Potential for Combined Treponemal/Nontreponemal Rapid Point-of-Care Test and Treponema pallidum Polymerase Chain Reaction in the Diagnosis of Gestational and Congenital Syphilis in a Low-Resource, High-Prevalence Setting: Pilot Data From Malawi [0.03%]
结合梅毒/非梅毒快速现场检测和苍白密螺旋体聚合酶链反应在资源匮乏且发病率高的地区诊断妊娠期和先天性梅毒的潜力：马拉维试点数据
Deirdre J Foley,Vita Nyasulu,Chifundo Kondoni et al.
Deirdre J Foley et al.
Background: Congenital syphilis (CS) remains a major cause of stillbirth and neonatal morbidity, with an estimated 700,000 cases and 390,000 adverse birth outcomes annually. We evaluated the diagnostic utility of combined...
Estimating the Value of Novel Tests for Active Syphilis in Zimbabwe: How Much Overtreatment Can Be Avoided? [0.03%]
估计津巴布韦活动性梅毒新型检测价值：可以避免过度治疗多少？
Robyn M Stuart,Michael Marks,Chido Dziva Chikwari et al.
Robyn M Stuart et al.
Background: Syphilis diagnosis in resource-limited settings relies on syndromic management and treponemal-based antibody screening tests that cannot distinguish active infection from past-treated infection, both of which ...
The Road to Elimination of Mother-to-Child Transmission of Syphilis in Malawi: A Mixed-Methods Analysis of Health System Readiness [0.03%]
马拉维消除梅毒母婴传播的道路：卫生系统准备情况的混合方法分析
Vester Gunsaru,Rebecca Husband,Zacharia Kafuwa et al.
Vester Gunsaru et al.
Background: This study evaluated health system readiness in Malawi for elimination of mother-to-child transmission (EMTCT) of syphilis against World Health Organization (WHO) validation criteria by identifying key health ...
Congenital Syphilis Elimination in Latin America: A Systematic Analysis of Policy and Progress [0.03%]
拉美地区先天梅毒消除政策与进展的系统分析
Angelica E Miranda,Jodie A Dionne,Bernardo Nuche-Berenguer et al.
Angelica E Miranda et al.
Background: Syphilis in pregnancy and congenital syphilis (CS) remain major public health challenges in Latin America despite long-standing elimination initiatives. CS incidence continues to rise, although diagnosis and t...
Remco P H Peters,Arlene C Seña,Alexander L Greninger et al.
Remco P H Peters et al.
Overview of the Shanghai International Syphilis Symposium (SISS 2025) [0.03%]
上海国际梅毒 symposium (SISS 2025) 简介
Pingyu Zhou,Justin D Radolf
Pingyu Zhou
Doxycycline post-exposure prophylaxis may dramatically reduce syphilis among gay, bisexual, and other men who have sex with men: a modeling study [0.03%]
多西环素暴露后预防可能显著减少男男性行为者当中的梅毒：一项建模研究
Patrick A Clay,David A Jackson,Laura H Bachmann et al.
Patrick A Clay et al.
Background: Syphilis cases in the United States have surged over the past decade, and cases are highest among gay, bisexual, and other men who have sex with men (GBMSM). The CDC recommends doxycycline post-exposure prophy...
MEASURING DOXYPEP USE RELATIVE TO STI RATES AT A SAN FRANCISCO STI CLINIC REVEALS RACIAL INEQUITIES IN DISEASE PREVENTION IMPACT [0.03%]
测量旧金山一家性病诊所的Doxypep使用相对于性传播感染率，揭示了疾病预防影响的种族不平等现象
Jason S Melo,Trang Q Nguyen,Oliver Bacon et al.
Jason S Melo et al.
Background: Doxycycline postexposure prophylaxis (doxyPEP) must reach people at high risk for bacterial STIs to reduce STI rates and inequities. PrEP-to-Need Ratios (PNR) identified inequities in PrEP by measuring PrEP pr...
Validation of diagnostic codes for identifying chlamydial infections from TriNetX electronic health record data in the United States [0.03%]
验证TriNetX电子健康档案数据中识别美国沙眼衣原体感染诊断代码的准确性
Lin Li,Kexin Zhu,Hosn Nabaa et al.
Lin Li et al.
Background: The accuracy of diagnostic codes for chlamydial infections in electronic health records (EHR) is understudied. TriNetX, a global federated database, provides real-time access to patient-level EHRs, but its sui...