Intestinal Barrier Dysfunction in Inflammatory Bowel Disease: Pathophysiology to Precision Therapeutics [0.03%]
炎症性肠病的肠道屏障功能障碍:从病理生理学到精准治疗
Balachandar Selvakumar,Rani Samsudin
Balachandar Selvakumar
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is characterized by chronic gastrointestinal inflammation and disruptions in the intestinal barrier, commonly referred to as "intestinal barrier dysfunction...
Reply: Barriers and Opportunities for Resilience Programs in IBD: Insights from the SMART Project [0.03%]
回复:SMART项目对炎症性肠病韧性项目的障碍和机遇的见解
Chung Sang Tse
Chung Sang Tse
Efficacy and Safety with Upadacitinib by Baseline Corticosteroid Use in Patients with Moderately to Severely Active Crohn's Disease [0.03%]
基线糖皮质激素使用情况下的乌帕替尼治疗中至重度活动性克罗恩病的有效性和安全性
Marla C Dubinsky,Geert DHaens,Olivier Dewit et al.
Marla C Dubinsky et al.
Importance and objective: Upadacitinib, an oral, reversible Janus kinase inhibitor, is approved for the treatment of moderate-to-severe Crohn's disease (CD). Limiting corticosteroid exposure is an important goal in treati...
Early Switching to Subcutaneous Infliximab as a Pragmatic Strategy for Optimized Inflammatory Bowel Disease Care [0.03%]
早期切换至英夫利西单抗皮下注射作为优化炎症性肠病治疗的务实策略
Kyuwon Kim,Byong Duk Ye
Kyuwon Kim
Luisa Bertin,Edoardo Vincenzo Savarino
Luisa Bertin
Home-based capillary blood sampling represents a paradigm shift toward patient-centered IBD monitoring, offering particular advantages for pediatric populations while requiring external validation before widespread clinical implementation. ...
Implementation of a Capillary Blood Self-Sampling Technique at Home for Monitoring of Patients With IBD [0.03%]
居家实施毛细血管血自我采样技术用于炎症性肠病患者的监测
Gillian S Schuurman,Wouter Tiel Groenestege,Meike M C Hirdes et al.
Gillian S Schuurman et al.
Background: Remote healthcare aims to improve the management of inflammatory bowel disease (IBD) patients by reducing hospital visits. This is the first study to assess capillary blood sampling at home for routine measure...
Comments on the Study of Colonic Taste Receptors, Fecal Amino Acids, and Ulcerative Colitis: Methodological Considerations for Enhanced Generalizability [0.03%]
关于结肠味觉受体、粪便氨基酸和溃疡性结肠炎研究的评论:提高普适性的方法学考虑因素
Kaiyan Liu,Jiaqi Wang,Jie Li
Kaiyan Liu
Characterization of Intestinal Mycobiome in Surgical Resections from Inflammatory Bowel Disease Patients: A Deeper Analysis in Complicated Crohn's Disease Phenotypes [0.03%]
炎症性肠病手术切除组织的肠道真菌微环境研究:复杂型克罗恩病表型的深入分析
Andrea Cejudo-Garcés,Miguel Carda-Diéguez,Francisco Navarro-Vicente et al.
Andrea Cejudo-Garcés et al.
Background: Inflammatory bowel disease (IBD), which encompasses ulcerative colitis (UC) and Crohn's disease (CD), is a chronic condition characterized by recurrent intestinal inflammation and complications. Despite extens...
Perioperative anti-α4β7 Integrin Blockade Alters Wound Cell Infiltrate but Not the Functional Outcome of Ileocecal Anastomoses in Mice With Crohn's-like Ileitis [0.03%]
抗α4β7整合素在类克罗恩病回肠炎小鼠术后对伤口细胞浸润的影响但不影响回盲部吻合口的功能预后
Peggy Berlin,Annabel Fischer,Wendy Bergmann-Ewert et al.
Peggy Berlin et al.
Background and aims: Crohn's disease (CD) itself is discussed as risk factors for anastomotic leakage (AL) after ileocecal resection (ICR). In order to gain insight into the mechanisms of anastomotic healing (AH) in Crohn...