IBD in transition: a decade of data from the Malaysian Kinta Valley cohort [0.03%]
炎症性肠病的转型：来自马来西亚金塔山谷队列十年的数据
Ida Hilmi,Xin-Hui Khoo,David Yi-Vern Kwong et al.
Ida Hilmi et al.
Background and aims: Inflammatory bowel disease (IBD) is emerging in the Asia-Pacific region including Malaysia. The aim of this study is to compare the current incidence and prevalence of IBD in Malaysia from the previou...
Impact of advanced therapy initiation on antibiotic dependence in chronic pouchitis [0.03%]
早期启动生物制剂治疗对慢性回肠储袋炎抗生素依赖的影响
Yushan Pan,Katie A Dunleavy,Ashwin N Ananthakrishnan
Yushan Pan
Background: A quarter of patients with ulcerative colitis who undergo total proctocolectomy with ileal pouch-anal anastomosis experience chronic pouchitis. While advanced therapies (ATs) are effective in some patients, th...
Transperineal contrast-enhanced ultrasound: a rapid and reliable tool for differentiating abscesses from inflammatory masses in perianal Crohn's disease [0.03%]
经会阴期增强超声：鉴别肛周克罗恩病脓肿与炎症性包块的快速可靠工具
Giovanni Maconi,Cristina Bezzio,Adam Saleh et al.
Giovanni Maconi et al.
Background and aim: Perianal abscesses are serious complications of Crohn's disease (CD) requiring timely and accurate diagnosis. Contrast-enhanced ultrasound (CEUS), which in abdominal intestinal ultrasound (IUS) has sho...
Matrix metalloproteinases in intestinal fibrosis and fibrostenosing Crohn's disease: Current evidence, mechanistic hypotheses, and translational challenges [0.03%]
肠纤维化和瘢痕型克罗恩病中基质金属蛋白酶的现有证据、机制假设及转化挑战
Thierry Kochkarian,Kevin M Lopez,Rongliwen Ou et al.
Thierry Kochkarian et al.
Fibrostenosing complications in Crohn's disease arise from mixed transmural remodeling that includes inflammation, fibrosis, and muscular hypertrophy/hyperplasia. Matrix metalloproteinases (MMPs) are implicated in extracellular matrix turno...
Response to "Epidemiology of IBD in Malaysia: a rare longitudinal lens in Asia" [0.03%]
对《马来西亚炎症性肠病的流行病学：亚洲罕见的纵向视角》的观点回应
Ida Hilmi,Xin-Hui Khoo,David Yi-Vern Kwong et al.
Ida Hilmi et al.
Early transmural response assessed by intestinal ultrasound predicts long-term clinical remission in patients with IBD: Results from the TRUST BEYOND study [0.03%]
TRUST BEYOND研究的成果：早期肠壁反应可由肠道超声评估，并预测IBD患者的长期临床缓解
Torsten Kucharzik,Ulf Helwig,Frank Seibold et al.
Torsten Kucharzik et al.
Background: The study sought to prospectively examine clinical, biochemical, and transmural outcomes. Transmural outcomes are assessed by ultrasound after 1 year in patients with inflammatory bowel disease (IBD) treated i...
Clinicopathological features and cancer-specific survival in young patients with ulcerative colitis-associated colorectal neoplasia: a nationwide cohort study in Japan [0.03%]
日本全国队列研究：青年溃疡性结肠炎相关结直肠肿瘤的临床病理特征和癌症特异性生存率
Takahide Shinagawa,Koichi Komatsu,Motoi Uchino et al.
Takahide Shinagawa et al.
Background: The incidence of ulcerative colitis-associated colorectal neoplasia (UCAN) is increasing, but clinicopathological features and outcomes in young patients remain unclear. We aimed to clarify the characteristics...
Prevalence of inflammatory bowel disease across states: estimates based on claims database [0.03%]
基于索赔数据库下的炎症性肠病的患病率及各州间的差异估算
Hansol Kang,Kate L Karlin,Colleen M Brensinger et al.
Hansol Kang et al.
Data derived from our previously published pooled administrative claims database analysis were applied to estimate race-weighted state-specific prevalences of inflammatory bowel diseases in the United States to support public health, clinic...
Translating multiomics prediction into clinical care in Crohn's disease: Moving beyond proof of concept [0.03%]
从概念验证迈向临床护理：多组学预测在克罗恩病中的应用
Foekjen E Veenstra,Maximilian G Griesbaum,Arno R Bourgonje
Foekjen E Veenstra
Reply: "Entering a new GALAXI: The importance of long-term data in Crohn's disease clinical trials" [0.03%]
致编辑：关于克罗恩病临床试验中长期数据重要性的评论："进入新'银河系'"
Anita Afzali,Rian Van Rampelbergh
Anita Afzali