Fecal calprotectin is an accurate noninvasive screening tool for pouchitis [0.03%]
粪便钙卫蛋白对筛查回肠袋炎是一种准确的非侵入性检查手段
Sérgio Bronze,Susanne Ibing,Darwin Jimenez et al.
Sérgio Bronze et al.
Background: Pouchitis is the most common complication after ileal pouch anal anastomosis (IPAA), yet symptoms are non-specific, and diagnosis typically requires pouchoscopy. Fecal calprotectin (FC) is an established infla...
Early Intestinal Ultrasound Assessment Predicts Therapy Response: An Easy Tool for Clinical Decision-Making [0.03%]
早期肠道超声评估可预测治疗反应:一种临床决策的简便工具
Elena De Cristofaro,Francesca Zorzi,Alice Colella et al.
Elena De Cristofaro et al.
Background: Transmural healing (TH) has emerged as a therapeutic target in Crohn's disease (CD), providing a more comprehensive indicator of deep remission than mucosal healing alone. Intestinal ultrasound (IUS) is a noni...
Prevalence of disability in inflammatory bowel disease: a systematic review and meta-analysis [0.03%]
炎症性肠病残疾患病率的系统评价和meta分析
Olga Maria Nardone,Giulio Calabrese,Alexander C Ford et al.
Olga Maria Nardone et al.
Background and aims: Disability is a multidimensional concept that includes physical, psychological, and social limitations affecting individuals with inflammatory bowel disease (IBD). Disability is shaped by cultural and...
Incidence of acne in patients with inflammatory bowel disease treated with Janus kinase inhibitors: a systematic review and meta-analysis [0.03%]
Janus激酶抑制剂治疗炎症性肠病患者的痤疮发生率:系统评价和meta分析
Mohammed Nabil Quraishi,Maryam A Alahmad,Thaer Khaleel Swaid et al.
Mohammed Nabil Quraishi et al.
Background: Janus kinase (JAK) inhibitors are effective oral therapies for inflammatory bowel disease (IBD). While acne is a known adverse event in dermatological cohorts, its incidence and risk factors in the IBD populat...
Mirikizumab four-year sustained and durable efficacy and safety in ulcerative colitis: Final findings from the LUCENT-3 open-label extension study [0.03%]
Mirikizumab在溃疡性结肠炎中的四年持续有效性和安全性:LUCENT-3开放标签延长研究的最终结果
Bruce E Sands,David B Clemow,Geert DHaens et al.
Bruce E Sands et al.
Background: Mirikizumab, an anti-interleukin-23 monoclonal antibody targeting the p19 subunit, has shown efficacy in inducing and maintaining clinical remission in patients with moderately-to-severely active ulcerative co...
Mesenchymal stem cell-derived exosomes derived from induced pluripotent stem cells ameliorate inflammation and promote mucosal healing via miR-34a-5p in Crohn disease [0.03%]
人诱导多能干细胞来源的间充质干细胞源性外泌体通过含miR-34a-5p促进克罗恩病肠黏膜愈合及抗炎作用研究
Ting Feng,Yun Qiu,Baili Chen et al.
Ting Feng et al.
Background: Crohn disease (CD) is a chronic, recurrent inflammatory bowel disease. Mesenchymal stem cell-derived exosomes (MSC-Exos) have emerged as promising cell-free treatments for CD. ...
Unique challenges faced by tweens and teens with inflammatory bowel disease: a global perspective [0.03%]
全球视角下青少年炎症性肠病患者的独特挑战
Irina Geiculescu,Barbara Joanna Niklinska-Schirtz,Sachith Munasinghe et al.
Irina Geiculescu et al.
Access to quality healthcare for individuals with chronic diseases like inflammatory bowel disease (IBD) remains a global challenge. Tweens (aged 9-12 years) and teens (typically aged 13-19 years) with IBD face unique challenges compared to...
Abigail Robbertz,Kevin Hommel,Laurie Keefer et al.
Abigail Robbertz et al.
Background: Youth with inflammatory bowel diseases (IBDs) are at an increased risk for mental health concerns compared to healthy peers. Given the unique psychosocial risk factors involved in living with IBD, it can be ch...
Updated pathologic classification of inflammatory bowel disease-associated colorectal dysplasia: A guide for clinicians [0.03%]
炎症性肠病相关结直肠肿瘤性病变的病理分类更新:临床医师指南
Noam Harpaz,Robert D Odze
Noam Harpaz
This review provides a guide to the pathology of the most recent classification of inflammatory bowel disease-associated neoplastic precursor lesions. Its objective is to orient clinicians to the morphological and terminological framework u...
Daniele Napolitano,Mattia Bozzetti,Valentina Vanzi et al.
Daniele Napolitano et al.
Background: Bowel urgency is a distressing and often underrecognized symptom of inflammatory bowel disease (IBD). It represents a sudden and compelling need to defecate that is difficult to defer and strongly affects pati...