Prognostic Utility of the Cachexia Index in Resectable and Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy [0.03%]
术前新辅助化疗可切除和交界性可切除胰腺癌的恶病质指数预后价值评估
Satoru Tsuruta,Keinosuke Ishido,Hayato Nagase et al.
Satoru Tsuruta et al.
Objectives: The cachexia index (CXI), integrating skeletal muscle mass, serum albumin, and the neutrophil-to-lymphocyte ratio, has been proposed as a marker of cancer-related cachexia. The objective of this study was to a...
Chemotherapy for Unresectable Pancreatic Cancer Complicated by Disseminated Intravascular Coagulation: A Retrospective Cohort Study [0.03%]
一项回顾性队列研究:化疗对不可切除的伴有弥散性血管内凝血的胰腺癌的作用效果
Kohei Nagata,Takayuki Ando,Hiroki Kawanaka et al.
Kohei Nagata et al.
Objectives: This study aimed to characterize the clinical features and prognosis of advanced pancreatic cancer (APC) complicated by disseminated intravascular coagulation (DIC), with a particular focus on distinguishing b...
Association Between Serum Uric Acid and Intrapancreatic Fat Deposition in a General Health Check-up Population: A Cross-sectional Study [0.03%]
血尿酸水平与健康体检人群胰腺内脂肪沉积的关系:横断面研究
Yu Wang,Yiping Zhang,Dingzhe Zhang et al.
Yu Wang et al.
Objectives: While the health risks associated with intrapancreatic fat deposition (IPFD) have attracted considerable attention, its contributing or risk factors remain poorly understood. Elevated uric acid (UA) levels are...
Primary Hyperparathyroidism-Induced Acute Pancreatitis: Case Report and Systematic Review [0.03%]
原发性甲状旁腺功能亢进所致急性胰腺炎:病例报告及系统评价
Fei Che,Dongfeng Lv,YaDong Liu et al.
Fei Che et al.
Background: Primary hyperparathyroidism (PHPT) is a rare but notable metabolic cause of acute pancreatitis (AP). Early diagnosis and surgical intervention are crucial to prevent recurrence and improve prognosis. ...
Early-onset Pancreatic Cancer is Associated With Better Survival: A SEER Population-Based Analysis [0.03%]
基于SEER的队列研究:早期胰腺导管腺癌患者的生存预后较好分析
Kaewkwan Liengswangwong,Stephen J Pandol
Kaewkwan Liengswangwong
Objectives: The incidence of early-onset pancreatic cancer is increasing worldwide. This study aimed to evaluate whether survival differences between early and late-onset pancreatic cancer persist after adjustment for tum...
Outcomes of Post-Endoscopic Ultrasound Pancreatic Cancer Compared to Detected Pancreatic Cancer: A Multicenter Cohort Study [0.03%]
内镜超声后胰腺癌预后与发现的胰腺癌的比较:一项多中心队列研究
Rahul Karna,Himsikhar Khataniar,Omar Al Taani et al.
Rahul Karna et al.
Background and aims: Endoscopic ultrasound (EUS) can detect pre-malignant lesions in pancreas. Despite advances in training, EUS remains an operator dependent procedure and interval pancreatic cancer (PC) can be diagnosed...
Efficacy and Safety of Remimazolam versus Midazolam for Sedation during Endoscopic Ultrasound-Guided Tissue Acquisition in Patients with Solid Pancreatic Lesions [0.03%]
右美托咪定与咪达唑仑在实性胰腺病变患者内镜超声引导下组织获取术中的镇静效果及安全性比较研究
Yuki Tanisaka,Shomei Ryozawa,Masafumi Mizuide et al.
Yuki Tanisaka et al.
Objectives: Remimazolam is an ultra-short-acting benzodiazepine with a shorter pharmacokinetic half-life than midazolam. This study compared the efficacy and safety of remimazolam and midazolam for sedation during endosco...
Outcomes of Surveillance Program for Individuals at High-Risk of Pancreatic Adenocarcinoma [0.03%]
高风险胰腺导管腺癌个体的监测项目的预后研究
Leena S Penumalee,Yangruijue Ma,Ruohui Chen et al.
Leena S Penumalee et al.
Objectives: Individuals at high-risk (HRI) of developing pancreatic adenocarcinoma (PDAC) are offered intensive screening to detect PDAC at an early, curable stage. There is scant data on how HRI PDAC screening programs p...
ITGB4 Activates the Pentose Phosphate Pathway to Reduce the Sensitivity of Pancreatic Adenocarcinoma to Gemcitabine [0.03%]
ITGB4活化戊糖磷酸途径以降低胰腺癌对吉西他滨的敏感性
Xianfei Zhou,Fan Yang,Luoshun Huang et al.
Xianfei Zhou et al.
Background: Integrinβ4 (ITGB4), a transmembrane adhesion molecule, is closely associated with chemotherapy resistance in tumor cells. The pentose phosphate pathway (PPP) is a critical metabolic pathway that enables tumor...