Dietary management and feeding considerations of pediatric aerodigestive and upper gastrointestinal motility disorders: A position paper by the NASPGHAN Neurogastroenterology and Motility Committee [0.03%]
儿童呼吸道消化道及上消化道运动障碍的饮食管理和喂养注意事项：NASPGHAN神经胃肠病和动力委员会立场文件
Khalil El-Chammas,Kirsten B Jones,Joan Arvedson et al.
Khalil El-Chammas et al.
Objective: Pediatric aerodigestive and upper gastrointestinal (UGI) motility disorders are common and may be associated with compromised nutritional status and decreased quality of life. Traditional dietary recommendation...
The impacts of energy and protein provision on anthropometric changes in infants with critical congenital heart disease [0.03%]
能量和蛋白质供给对危重先天性心脏病婴儿生长发育的影响研究
Colin R Tang-Whitmore,Cydney Coleman,Brittany Faanes et al.
Colin R Tang-Whitmore et al.
Objectives: Malnutrition in patients with critical congenital heart disease (CCHD) is associated with worse outcomes, however, feeding challenges, and changes in metabolic demands obscure the relationship between nutrient...
Reevaluating the rule of two's: Age and epidemiological variations in Meckel's diverticulum [0.03%]
梅克尔憩室的年龄和流行病学变化规律的再评价
Ashley Polachek,Megha S Mehta,Ahmed Shalaby et al.
Ashley Polachek et al.
Objective: To evaluate the clinical characteristics, diagnostic modalities, and age-related variation of Meckel's diverticulum (MD) using data from a nationwide pediatric inpatient database and a single-center institution...
Subcutaneous infliximab in pediatric inflammatory bowel disease: Sustained remission, predictable pharmacokinetics, and real-world US implementation [0.03%]
儿科炎症性肠病的皮下注射英夫利昔单抗：持续缓解、可预测的药代动力学和真实世界的美国实施经验
Patricia M Hughes,Nanci Pittman,Keith Benkov et al.
Patricia M Hughes et al.
Objectives: Subcutaneous infliximab (IFX-SC) offers a convenient alternative to intravenous infliximab (IFX-IV) in inflammatory bowel disease (IBD) with more stable concentrations. Pediatric experience remains limited. We...
Exclusive enteral nutrition containing transforming growth factor-β improves intestinal barrier function in a colitis mouse model [0.03%]
含有转化生长因子-β的 exclusive enteral营养改善colitis小鼠模型的肠道屏障功能
Kawthar Boumessid,Vickie Lacroix,Ekaterina Ovtchinnikova et al.
Kawthar Boumessid et al.
Objectives: Exclusive enteral nutrition (EEN) is the first-line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the...
Dyssynergic defecation in adolescents with constipation: Anorectal manometry findings [0.03%]
青少年便秘的协同性排便障碍：肛直肠测压结果
Mustafa Sadek,Alaa Almallouhi,Olla Darwish et al.
Mustafa Sadek et al.
Objectives: To describe and compare anorectal manometry findings in constipated adolescents with and without dyssynergic defecation (DD). Methods: ...
The illusion of competence: Evaluating the clinical reasoning of large language models in pediatric gastroenterology [0.03%]
胜任的错觉：评估大型语言模型在儿科胃肠病学中的临床推理能力
Yasin Maruf Ergen,Selçuk Teke,Edibe Gözde Başaran et al.
Yasin Maruf Ergen et al.
Objective: To evaluate the diagnostic accuracy and clinical reasoning of three frontier large language models (LLMs) across standardized pediatric gastroenterology, hepatology, and nutrition (PGHN) clinical vignettes. ...
Does diagnosis by biopsy versus serology-only affect follow-up in celiac disease? [0.03%]
活检与仅使用血液检测诊断的乳糜泻患者随访方式是否不同？
Maria Cristina Pacheco,Kai Kokesh,Jane Dickerson et al.
Maria Cristina Pacheco et al.
Objectives: Serology-only diagnosis of celiac disease is increasing, but few recent studies have looked at the outcomes of patients undergoing this approach. The aim of this study was to evaluate difference in clinical fo...
Gut microbiome in pediatric acute pancreatitis and Crohn's disease versus irritable bowel syndrome and healthy controls [0.03%]
急性胰腺炎和克罗恩病患儿的肠道微生物组与肠易激综合征及健康对照组的比较研究
Neha R Santucci,Chinenye R Dike,Jenny Hellmann et al.
Neha R Santucci et al.
Objectives: Pediatric acute pancreatitis (AP), Crohn's disease (CD), and irritable bowel syndrome (IBS) are associated with gut dysbiosis, but differences and similarities between conditions are unknown. We hypothesized t...