Integrated imaging approach to tumor model mice using bioluminescence imaging and magnetic resonance imaging [0.03%]
基于生物发光及磁共振的肿瘤模型小鼠综合影像学研究方法
Yusuke Inoue,Yoshitaka Masutani,Shigeru Kiryu et al.
Yusuke Inoue et al.
We developed an integrated imaging method using bioluminescence imaging (BLI) and magnetic resonance imaging (MRI) and applied it to mouse tumor monitoring. BLIs and MRIs were successively acquired from mice fixed on a transparent flat plat...
Eric J Chaney,Li Tang,Rong Tong et al.
Eric J Chaney et al.
Tumor metastases occur through both the cardiovascular and lymphatic circulations. However, the majority of nanoparticle biodistribution studies have been focused on the cardiovascular circulation. In this study, we report the formulation o...
In vivo scintigraphic imaging of antitumor effects by combined radioiodine therapy and human sodium iodide symporter gene immunotherapy [0.03%]
联合放射性碘治疗和人钠碘转运蛋白基因免疫治疗的抗肿瘤效应的体内闪烁成像研究
Yun Choi,Yong Hyun Jeon,Jin Ho Paik et al.
Yun Choi et al.
In a previous study, we demonstrated that pcDNA3.1/hNIS (human sodium iodide symporter) vaccination generated hNIS-associated CD8+IFN-gamma+ (interferon-gamma) T cells, which are known to be involved in antitumor immunity. However, the immu...
Molecular imaging agents specific for the annulus fibrosus of the intervertebral disk [0.03%]
用于椎间盘纤维环的分子影像剂
Summer L Gibbs-Strauss,Carrie Vooght,Kenneth M Fish et al.
Summer L Gibbs-Strauss et al.
Low back pain is a prevalent medical condition that is difficult to diagnose and treat. Current imaging methods are unable to correlate pain reliably with spinal structures, and surgical removal of painful damaged or degenerating disks is t...
Ryan Gessner,Paul A Dayton
Ryan Gessner
Ultrasound imaging has long demonstrated utility in the study and measurement of anatomic features and noninvasive observation of blood flow. Within the last decade, advances in molecular biology and contrast agents have allowed researchers...
Review
Molecular imaging. 2010 Jun;9(3):117-27. DOI: 2010
Margaret A Wheatley,John Lewandowski
Margaret A Wheatley
Tumor imaging by ultrasound is greatly enhanced by the use of ultrasound contrast agents (UCAs), stabilized, gas-filled bodies. They are generally less than 7 microm to pass freely through the capillary bed. Development of a nano-sized agen...
Improving sensitivity in ultrasound molecular imaging by tailoring contrast agent size distribution: in vivo studies [0.03%]
通过调整对比剂尺寸分布提高超声分子成像敏感度：体内研究
Jason E Streeter,Ryan Gessner,Iman Miles et al.
Jason E Streeter et al.
Molecular imaging with ultrasound relies on microbubble contrast agents (MCAs) selectively adhering to a ligand-specific target. Prior studies have shown that only small quantities of microbubbles are retained at their target sites, therefo...
Simplified [18F]FDG image-derived input function using the left ventricle, liver, and one venous blood sample [0.03%]
基于左心室、肝脏和一次静脉采血的[18F]fdg简化的图像输入函数
Mohammed Noor Tantawy,Todd E Peterson
Mohammed Noor Tantawy
A relatively simple, almost entirely noninvasive imaging-based method is presented for deriving arterial blood input functions for quantitative [(18)F]2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomographic (PET) studies in rodents. ...
Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging [0.03%]
采用光谱成像无创监测乳腺癌原位模型中荧光蛋白mRFP1和mCherry标记的溶瘤腺病毒
Anton V Borovjagin,Lacey R McNally,Minghui Wang et al.
Anton V Borovjagin et al.
Genetic capsid labeling of conditionally replicative adenoviruses (CRAds) with fluorescent tags offers a potentially more accurate monitoring of those virotherapy agents in vivo. The capsid of an infectivity-enhanced CRAd, Ad5/3, delta 24, ...
Positron emission tomography for serial imaging of the contused adult rat spinal cord [0.03%]
用于成年大鼠脊髓挫伤序贯成像的正电子发射断层扫描技术
Rishi D S Nandoe Tewarie,Jianhua Yu,Jurgen Seidel et al.
Rishi D S Nandoe Tewarie et al.
We investigated whether small-animal positron emission tomography (PET) could be used in combination with computed tomography (CT) imaging techniques for longitudinal monitoring of the injured spinal cord. In adult female Sprague-Dawley rat...