Multifunctional synthetic poly(L-glutamic acid)-based cancer therapeutic and imaging agents [0.03%]
一种基于聚左旋谷氨酸的多功能癌症治疗及诊断试剂
Marites P Melancon,Chun Li
Marites P Melancon
Modern polymer chemistry has led to the generation of a number of biocompatible synthetic polymers that have been increasingly studied as efficient carriers for drugs and imaging agents. Synthetic biocompatible polymers have been used to im...
Review
Molecular imaging. 2011 Feb;10(1):28-42. DOI: 2011
Lynn L Bergeson
Lynn L Bergeson
Domestic laws, their implementing regulations and policies, and government and private-party governance programs are now being carefully reviewed and revised to enhance their utility to manage the potential risks posed by nanoscale material...
Magdalena Swierczewska,Seulki Lee,Xiaoyuan Chen
Magdalena Swierczewska
Multimodal molecular imaging can offer a synergistic improvement of diagnostic ability over a single imaging modality. Recent development of hybrid imaging systems has profoundly impacted the pool of available multimodal imaging probes. In ...
Julie L Sutcliffe
Julie L Sutcliffe
Editorial
Molecular imaging. 2011 Feb;10(1):1. DOI: 2011
Semiautomatic algorithm for lymph node analysis corrected for partial volume effects in combined positron emission tomography-computed tomography [0.03%]
联合正电子发射断层显像/计算机体层摄影淋巴结半自动分析算法及部分容积效应校正法
Ralph A Bundschuh,Markus Essler,Julia Dinges et al.
Ralph A Bundschuh et al.
Positron emission tomography-computed tomography (PET-CT) is superior compared to stand-alone PET in evaluation of malignancies. Few studies have employed high-resolution structural information to correct PET. We designed a semiautomatic al...
Gastroenteropancreatic neuroendocrine tumors: standardizing therapy monitoring with 68Ga-DOTATOC PET/CT using the example of somatostatin receptor radionuclide therapy [0.03%]
生长抑素受体放射性核素治疗胃肠道胰神经内分泌肿瘤的疗效评价：以68Ga-DOTATOC PET/CT为例规范其监测标准
Wolfgang Luboldt,Holger Hartmann,Bärbel Wiedemann et al.
Wolfgang Luboldt et al.
The purpose of this study was to standardize therapy monitoring of hepatic metastases from gastroenteropancreatic neuroendocrine tumors (GEP-NETs) during the course of somatostatin receptor radionuclide therapy (SRRT). In 21 consecutive pat...
Evaluation of the reversal of multidrug resistance by MDR1 ribonucleic acid interference in a human colon cancer model using a Renilla luciferase reporter gene and coelenterazine [0.03%]
评估用海肾萤光素酶报告基因和腔肠素的结肠癌人多药耐药模型中MDR1核糖核酸干扰对多药抗性的逆转效果
Yong Hyun Jeon,Seon-ae Bae,Yong Jin Lee et al.
Yong Hyun Jeon et al.
The reversal effect of multidrug resistance (MDR1) gene expression by adenoviral vector-mediated MDR1 ribonucleic acid interference was assessed in a human colon cancer animal model using bioluminescent imaging with Renilla luciferase (Rluc...
Click synthesis and biologic evaluation of (R)- and (S)-2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid for brain tumor imaging with positron emission tomography [0.03%]
用于正电子发射断层显像的(R)和(S)-2-氨基-3-[1-(2-[18F]氟乙基)-1H-[1,2,3]三唑-4-基]丙酸的点击合成及生物评价
Jonathan McConathy,Dong Zhou,Stephany E Shockley et al.
Jonathan McConathy et al.
The (R)- and (S)-enantiomers of 2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid (4) were synthesized and evaluated in the rat 9L gliosarcoma brain tumor model using cell uptake assays, biodistribution studies, and mi...
Experimental evaluation of depth-of-interaction correction in a small-animal positron emission tomography scanner [0.03%]
小动物正电子发射断层扫描仪中深度相互作用校正的实验评估
Michael V Green,Harold G Ostrow,Jurgen Seidel et al.
Michael V Green et al.
Human and small-animal positron emission tomography (PET) scanners with cylindrical geometry and conventional detectors exhibit a progressive reduction in radial spatial resolution with increasing radial distance from the geometric axis of ...
Nanoparticles for biomedical imaging: fundamentals of clinical translation [0.03%]
用于生物医学影像的纳米颗粒：临床转化的基本原理
Hak Soo Choi,John V Frangioni
Hak Soo Choi
Because of their large size compared to small molecules and their multifunctionality, nanoparticles (NPs) hold promise as biomedical imaging, diagnostic, and theragnostic agents. However, the key to their success hinges on a detailed unders...
Review
Molecular imaging. 2010 Dec;9(6):291-310. DOI: 2010