Magnetic resonance cell-tracking studies: spectrophotometry-based method for the quantification of cellular iron content after loading with superparamagnetic iron oxide nanoparticles [0.03%]
基于分光光度法的定量分析载入超顺磁性铁氧体纳米颗粒后的细胞含铁量的方法及其在磁共振细胞示踪研究中的应用
Ingrid Böhm
Ingrid Böhm
The purpose of this article is to present a user-friendly tool for quantifying the iron content of superparamagnetic labeled cells before cell tracking by magnetic resonance imaging (MRI). Iron quantification was evaluated by using Prussian...
ATP-binding cassette transporters modulate both coelenterazine- and D-luciferin-based bioluminescence imaging [0.03%]
ATP结合盒式转运蛋白可调节腔肠素和D- luciferin生物荧光素酶成像
Ruimin Huang,Jelena Vider,Inna Serganova et al.
Ruimin Huang et al.
Bioluminescence imaging (BLI) of luciferase reporters provides a cost-effective and sensitive means to image biological processes. However, transport of luciferase substrates across the cell membrane does affect BLI readout intensity from i...
Superparamagnetic iron oxide-enhanced magnetic resonance imaging of neuroinflammation in a rat model of radicular pain [0.03%]
超顺磁性铁氧体增强的磁共振成像在坐骨神经痛大鼠模型中的神经炎症检测
Daniel L J Thorek,Christine L Weisshaar,Julie C Czupryna et al.
Daniel L J Thorek et al.
In many clinical cases of radicular pain, no noticeable neuropathology is detected by conventional medical imaging strategies. Superparamagnetic iron oxide (SPIO) nanoparticles were evaluated as magnetic resonance contrast agents to specifi...
Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions [0.03%]
利用切伦科夫发光检测正电子发射断层显像示踪剂的术中成像技术
Jason P Holland,Guillaume Normand,Alessandro Ruggiero et al.
Jason P Holland et al.
Imaging the location and extent of cancer provides invaluable information before, during, and after surgery. The majority of "image-guided" methods that use, for example, positron emission tomography (PET) involve preoperative imaging and d...
Microfluidic-based 18F-labeling of biomolecules for immuno-positron emission tomography [0.03%]
基于微流控的生物分子18F标记用于免疫正电子发射断层扫描技术
Kan Liu,Eric J Lepin,Ming-Wei Wang et al.
Kan Liu et al.
Methods for tagging biomolecules with fluorine 18 as immuno-positron emission tomography (immunoPET) tracers require tedious optimization of radiolabeling conditions and can consume large amounts of scarce biomolecules. We describe an impro...
Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging [0.03%]
动态对比增强磁共振成像对异种移植肿瘤模型中西妥昔单抗联合伊立替康早期疗效的评估
Hyunki Kim,Karri D Folks,Lingling Guo et al.
Hyunki Kim et al.
Early pancreatic cancer response following cetuximab and/or irinotecan therapies was measured by serial dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) before and during therapy. Groups 1 to 4 (n = 6/group) of SCID mice beari...
Novel α(2)β(1) integrin-targeted peptide probes for prostate cancer imaging [0.03%]
新颖的α(2)β(1)整合素靶向肽探针用于前列腺癌显像
Chiun-Wei Huang,Zibo Li,Hancheng Cai et al.
Chiun-Wei Huang et al.
Accumulating experimental evidence indicates that overexpression of α(2)β(1) integrin may correlate with progression in human prostate cancer. The objective of this study was to design a novel imaging probe based on the Asp-Gly-Glu-Ala (D...
HiSStology: high spectral and spatial resolution magnetic resonance imaging detection of vasculature validated by histology and micro-computed tomography [0.03%]
HiSStology：通过组织学和微型计算机断层扫描验证的高光谱和空间分辨率磁共振血管成像技术
Chad R Haney,Charles A Pelizzari,Sean Foxley et al.
Chad R Haney et al.
High spectral and spatial resolution (HiSS) data, acquired with echo-planar spectroscopic imaging (EPSI), can be used to acquire water spectra from each small image voxel. These images are sensitive to changes in local susceptibility caused...
Imaging herpes simplex virus type 1 amplicon vector-mediated gene expression in human glioma spheroids [0.03%]
人胶质瘤球形体中的单纯疱疹病毒基因表达的成像技术研究
Christine Kaestle,Alexandra Winkeler,Raphaela Richter et al.
Christine Kaestle et al.
Vectors derived from herpes simplex virus type 1 (HSV-1) have great potential for transducing therapeutic genes into the central nervous system; however, inefficient distribution of vector particles in vivo may limit their therapeutic poten...
Preclinical evaluation of 68Ga-DOTA-minigastrin for the detection of cholecystokinin-2/gastrin receptor-positive tumors [0.03%]
68镓-DOTA-迷你胃泌素用于胆囊收缩素-2/胃泌素受体阳性肿瘤检测的临床前评估
Maarten Brom,Lieke Joosten,Peter Laverman et al.
Maarten Brom et al.
In comparison to somatostatin receptor scintigraphy, gastrin receptor scintigraphy using 111In-DTPA-minigastrin (MG0) showed added value in diagnosing neuroendocrine tumors. We investigated whether the 68Ga-labeled gastrin analogue DOTA-MG0...